Protein Alignment CG16789 and Iqca1l

DIOPT Version :10

• Sequence 1: NP_649910.3
• Gene: CG16789 / 41154
• FlyBaseID: FBgn0037712
• Length: 831
• Species: Drosophila melanogaster
• Sequence 2: NP_001019488.2
• Gene: Iqca1l / 499971
• RGDID: 1564789
• Length: 822
• Species: Rattus norvegicus
• Alignment Length: 874
• Identity: 344/874 - (39%)
• Similarity: 487/874 - (55%)
• Gaps: 99/874 - (11%)

  Fly     1 MSSTYFNDIWHQSQHECELLSTIDYERQHQDVETTVATMNAAVGSVAADADAKALLQSSLYEFYL 65
            ||...:..:|..|....|.:    .|::...:|..:..             .:...|..:...||
  Rat     1 MSEGTYQRLWEASHATLEEV----LEKEPSPLEPVLTR-------------ERQSFQYRISVLYL 48

  Fly    66 RYICLSNRLEDVYDNMIQPQKRQLVRKLLDACLGRVVELKHDLVNIDLMEFSYNDEVVERLRLTP 130
            .|:.|..|....||.|:|||||:|:|:|||...|||:|||.:||.:||.|....|.|::.|:|||
  Rat    49 YYLGLLRRFNLAYDQMVQPQKRRLLRRLLDGVAGRVLELKDELVRVDLCETHCLDRVLQELKLTP 113

  Fly   131 METELRIPRYFLRERQQELEFRKKTMHEILTKLGWLEEHE----LEETVTTEIEAIRMLQMHERA 191
            .:.|:.||:||..|:...::.|::.:.|||.:|..|...|    :..|     ||:.::|..|||
  Rat   114 ADLEVPIPKYFQLEQTSTMKARQQMLAEILARLEPLASQENLRGMSRT-----EALIIVQCAERA 173

  Fly   192 RQGRLRAHFMKEIRILKEKGKSEERTEKER--------SDSGLLAAMKIQKMWRGHTAR-RITRR 247
            |||||||.||:|||      |.|||..:.|        .|.|   |:.|||:|:|:..| ||.:.
  Rat   174 RQGRLRATFMREIR------KEEERDRRIRENGRQKFSQDQG---AIVIQKVWKGYLQRKRIEQD 229

  Fly   248 RKMEEMILIGMLPPPPAVVKERAEKLEKLQHNEKRYQAQAFYGKEFE-----ERQNALKEEIRAK 307
            |:| ||..|||||......::.|             .||||.|:|..     |::...:|.|...
  Rat   230 RRM-EMEFIGMLPSSSQTTRQNA-------------LAQAFVGEESRRTRQVEKEEEFQEAIAKT 280

  Fly   308 H-------GASMKEDIADEIRAWVKDCYDKTGKLPDFPSEDQGGSLHIFSRPGTESEHSRSSARS 365
            |       |..|||.:.|:||.|..:|:..||:.||:|.|..|||..||:....|.......|::
  Rat   281 HESLTETEGPDMKERMKDQIRQWFIECHALTGRFPDYPDEASGGSYLIFADKTPEQVRQELEAQA 345

  Fly   366 ----SKESRKTKDKSKSPARSGDLNVNE---NQDEEVSFQPAPSVCLPDIRAEIDLFNDTWRDKD 423
                .||..|.|||.|...........|   .:|.||.|:..||..:|.|.|..:.|...|:.:.
  Rat   346 QENKKKEQEKNKDKVKEKKEKKKKKTKEEKAKKDPEVMFKVLPSKSIPVINAGHEEFTSIWKSRY 410

  Fly   424 ETGVLSQAAYEDMIYSDKYQEVELEFRRAVDDVMRQEIELLQTAVGK---KVKKSSKKTRRSGKK 485
            :....||:...:.:..:|.::||:|.|..||::||||:..|:.||.:   :..||.||  :.|||
  Rat   411 DNKHPSQSFDSETLREEKRKQVEMEIRVQVDELMRQELRNLRLAVDREETRPLKSPKK--KGGKK 473

  Fly   486 S-KKKKEKDLTPDRTTESLYEELVTNGIIRKYPELRLKQFLGD-----KALT-ARIGTNPSPGDI 543
            | ||||||||||||:.:||:||||..|:|:|...:.|..::||     ..|| |.....||..||
  Rat   474 SGKKKKEKDLTPDRSVDSLFEELVVIGLIKKSLLVTLNDYIGDCLYLGSTLTLANKIPMPSLFDI 538

  Fly   544 RQILTEYCILPLGSDAIHNCTPLIRSILLAGPKGSGKKALLHAICTEVGAVLFDLTPANIVGKYP 608
            ||.:..|.:|.|||..||...||:|||||.||.|.|||.|:.|:|||.||.||||:|.|::||||
  Rat   539 RQNIALYGVLRLGSHDIHTMAPLVRSILLVGPSGMGKKMLVQAVCTETGANLFDLSPGNVMGKYP 603

  Fly   609 GKSGLIMLIHLVLKVSRLLQPAVIFMGDAERPFMKKIPKTD-RTDPKRLKKDLPKLIKNIAPEDR 672
            ||:|..:|:|:|.||:|:.||:||::|:.|:.|.|||||.: |.||||:||||.:..:.:.|.||
  Rat   604 GKNGSQLLMHIVFKVARVFQPSVIWIGNTEKTFYKKIPKEERRMDPKRIKKDLMRATRQLGPGDR 668

  Fly   673 VVFIGTSNLPWEADQKLLQSVYNRFIYIPRPDYGAMSHAWKTLLHDYSGGI---SNLDTSAMAKI 734
            |:.|||:..|..|:.|.|...|.|.::||||||.:....||.::.:...|:   .:||.||:|::
  Rat   669 VMLIGTTERPQLAEMKGLCRFYERILFIPRPDYASRYVLWKRMIENQGIGVQQTQSLDISALARV 733

  Fly   735 SDGYTIGSIDACLKEVMTCKRKLQLRTQPLTNAELINVLCSRDPVYREEEEAFESWWSKTPLGRR 799
            |||||.|.|...::.|:|.:|.|||..:||..:|.:..|...|||||||||:.:.|:.|||||::
  Rat   734 SDGYTPGHILQSIQSVLTERRLLQLTKKPLVASEFVVHLAKLDPVYREEEESLKEWFYKTPLGKK 798

  Fly   800 RQRFLELEEERLLEEQAQAAKQGNGNKKK 828
            ..:|.:.::|   .|:|:.||:   .|||
  Rat   799 NIKFTKDQQE---AEEARLAKE---KKKK 821

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG16789	NP_649910.3	DUF5401	<131..>307	CDD:375164	67/193 (35%)
		SpoVK	443..773	CDD:440232	164/343 (48%)
		P-loop containing Nucleoside Triphosphate Hydrolases	542..700	CDD:476819	84/158 (53%)
Iqca1l	NP_001019488.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	338..378		9/39 (23%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	457..484		15/28 (54%)
		P-loop containing Nucleoside Triphosphate Hydrolases	537..696	CDD:476819	84/158 (53%)