Protein Alignment CG16789 and Pex1

DIOPT Version :10

• Sequence 1: NP_649910.3
• Gene: CG16789 / 41154
• FlyBaseID: FBgn0037712
• Length: 831
• Species: Drosophila melanogaster
• Sequence 2: NP_652016.1
• Gene: Pex1 / 45460
• FlyBaseID: FBgn0013563
• Length: 1006
• Species: Drosophila melanogaster
• Alignment Length: 794
• Identity: 154/794 - (19%)
• Similarity: 268/794 - (33%)
• Gaps: 242/794 - (30%)

  Fly    47 AADADAKALLQSSLYEFYLRYICLSNRLEDVYDNMIQPQ---KRQLVRKLLDACLGRVV-ELKHD 107
            |||.|           :|:|...:.:.:||.....|.|.   ...|::.|....|.||| ..|..
  Fly   286 AADKD-----------YYVRVRTVEDDIEDDLPETIHPSIELNANLMKLLGIKELERVVLRPKTT 339

  Fly   108 LVNI--------------DLMEFSYNDEVVERLRLTPMETELRIPRYFLRERQQELEFRKKTMHE 158
            :||.              .:||.::...|:||.:..||        .|.:|....||      .:
  Fly   340 VVNFVEKIELFANKKTHYKIMENAFKRFVIERTQHKPM--------LFNQEEVVRLE------DD 390

  Fly   159 ILTKLGWLEEHELEETVTTEIEAIRMLQMHERARQGRLRAHFMKE--------IRILKEKGKSEE 215
            :|..:|.|.||                     .|...:.|.|:||        :|.:.|..|.|.
  Fly   391 LLVTVGILPEH---------------------FRYCVVDAQFLKESKIYAADLVRPVGEIIKEET 434

  Fly   216 RTEKERSDSGLLAAMKIQKMWRGHTARRITRRRKME-------------EMILIGMLPPPPAVVK 267
            ......|...|:...:..|:     ..::.:..:|.             .::|.|.......|:.
  Fly   435 PPTSPLSVQDLIQLPEYDKI-----VDQVVQELRMNLCLSADNSVMRQCNVLLAGASGTGKTVLV 494

  Fly   268 ERAEKLEKLQHNEKRYQAQAFYGKEFEERQNALKEEIRAKHGASMKEDIADEIRAWVKDCYDKTG 332
            ||.  |::|.........:.|:|...:.|:.               |.|..::|.....|
  Fly   495 ERI--LDQLSRKPDYCHFEFFHGSRSKGRKT---------------ESIQKDLRNIFTSC----- 537

  Fly   333 KLPDFPSEDQGGSLHIFSRPGTES--------------------EHSRSSA----RSSKESRKTK 373
             |...|:.....:|.:.:....|.                    :::.::|    .:..|.:...
  Fly   538 -LQHAPAIVVLENLDVLAHAAGEQSSQDGEYYNRMADTVYQLIVQYTTNNAIAVIATVNELQTLN 601

  Fly   374 DKSKSP---------ARSGDLNVNENQDEEVSFQPAPSVCLPDIRAEIDLFNDTWRDKDETGVLS 429
            .:..||         ||..:|   |..|.|        :.|.::.:.|::..|          |.
  Fly   602 KRLSSPRGRHVFQTVARLPNL---ERADRE--------IILRELCSHINVAKD----------LD 645

  Fly   430 QAAYEDMIYSDKYQEVELEFRRAVDDVMRQEIELLQTAVGKKVKKSSKKTRRSGKKSKKKKEKDL 494
            ...:.::  ::.|::.:|             ::.::.|:....:.|             |.:..|
  Fly   646 LVKFSNL--TEGYRKCDL-------------VQFVERAIFYAYRIS-------------KTQPLL 682

  Fly   495 TPDRTTESLYEELVTNGIIRKYPELRLKQFLGDKALTARIGTNPSPG--DIRQILTEYCILPLGS 557
            |.|:..|||..   ||....:  .::..|..|:.|....:.....||  .:..:|.|..:.|...
  Fly   683 TNDQLIESLEH---TNSYCLQ--GIQSNQRTGNDADANEMRVEELPGLESVVGVLEEVLMWPSRY 742

  Fly   558 DAIHNCTPLIR--SILLAGPKGSGKKALLHAICTEVGAVLFDLTPANIVGKYPGKSGLIMLIHLV 620
            ..|.|.:||..  .:||.||.|:||..|:..:.|.....:..:....::.||.|:|.  ..:..:
  Fly   743 PTIFNASPLRNQAGVLLYGPPGTGKTYLVSQLATSWNLRIISVKGPELLAKYIGQSE--ENVRNL 805

  Fly   621 LKVSRLLQPAVIFMGDAERPFMKKIPK-----TDRTDPKRLKKDLPKLIKNIAPEDRVVFIGTSN 680
            ...:|..:|.|:|..:    |....||     |..||  |:...|...:..:.....|..|..::
  Fly   806 FNRARSARPCVLFFDE----FDSLAPKRGHDSTGVTD--RVVNQLLTELDGVEGLQGVTVIAATS 864

  Fly   681 LPWEADQKLLQS-VYNRFIYIPRPD-------YGAMS-------------HAWKTLLHDYSGG-I 723
            .|...|..||:| ..:|.:..|.||       :.|:|             .|.||.  :|:|. |
  Fly   865 RPELLDPALLRSGRIDRLVECPLPDAPARVRIFEALSSTLSLDECVDFDWFAGKTA--NYTGADI 927

  Fly   724 SNLDTSA-MAKISD 736
            .::.||| ||.:.:
  Fly   928 QSILTSANMAAVKE 941

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG16789	NP_649910.3	DUF5401	<131..>307	CDD:375164	33/196 (17%)
		SpoVK	443..773	CDD:440232	73/326 (22%)
		P-loop containing Nucleoside Triphosphate Hydrolases	542..700	CDD:476819	40/165 (24%)
Pex1	NP_652016.1	PEX-1N	93..168	CDD:462729
		CDC48	365..983	CDD:273521	133/704 (19%)
		RecA-like_PEX1_r2	728..885	CDD:410934	40/164 (24%)