Protein Alignment CG16789 and Iqca1

DIOPT Version :10

• Sequence 1: NP_649910.3
• Gene: CG16789 / 41154
• FlyBaseID: FBgn0037712
• Length: 831
• Species: Drosophila melanogaster
• Sequence 2: NP_001418200.1
• Gene: Iqca1 / 316616
• RGDID: 1305311
• Length: 836
• Species: Rattus norvegicus
• Alignment Length: 865
• Identity: 328/865 - (37%)
• Similarity: 538/865 - (62%)
• Gaps: 67/865 - (7%)

  Fly     1 MSSTYFNDIWHQSQHECELLSTIDYERQHQDVETTVATMNAAVGSVAADADAKALLQSSLYEFYL 65
            ||:..:|::|||:|.  .|.|.:|.|.|    :.|....|            |.|:...|..||:
  Rat     1 MSNLMYNNMWHQTQE--ALNSLLDKESQ----KMTEPQKN------------KVLVFQMLATFYI 47

  Fly    66 RYICLSNRLEDVYDNMIQPQKRQLVRKLLDACLGRVVELKHDLVNIDLMEFSYNDEVVERLRLTP 130
            :|:.:...:|:|||.::.||||.|:||:||..:||::|||:::|.:::.||.|.|::::.::|:|
  Rat    48 KYVQIFRNMENVYDQIVHPQKRMLIRKILDGVMGRILELKNEMVELEMTEFHYFDDILQDMKLSP 112

  Fly   131 METELRIPRYFLRERQQELEFRKKTMHEILTKLGWLEEHELE---ETVTTEIEAIRMLQMHERAR 192
            .:.::.||||||:||.:.::.|:||:..||.:.| |...:::   :::..| ||::|:|:.||||
  Rat   113 QQLDVPIPRYFLKERLEVIKGREKTLARILDECG-LNLPDVKYAVKSIALE-EAVKMIQIAERAR 175

  Fly   193 QGRLRAHFMKEIRILKEKGKSEERTEKERSDSGLLAAMKIQKMWRGHTARRITRRRKMEEMILIG 257
            ||||||.|||:|.:.:.:.:..:....:.||: .|||::|||:|||....:.|.:.:.|||:.:|
  Rat   176 QGRLRAMFMKQIFLQECRAREMKLLGHKLSDT-TLAALQIQKVWRGFYQCKKTVKEREEEMVFLG 239

  Fly   258 MLPPP------PAVVKERAEKLEKLQHNEKRYQAQAFYGKEFEERQNALKEEIRAKHGASMKEDI 316
            |.|||      .|:|  ::|::..|     |.:.|..:.::::|...::||::|...||.:||.:
  Rat   240 MKPPPLFNEVSDAIV--QSEQVSNL-----RDELQLKHEQKYQEALVSIKEDLRLLEGADIKEHL 297

  Fly   317 ADEIRAWVKDCYDKTGKLPDFPSEDQGGSLHIFSRP----------GTESEHSRSSARSSKESRK 371
            .|:||.|..:|.:.||..|::|:|::|||..|||..          ..:.|..:|..:..||.::
  Rat   298 QDQIRQWFIECRNLTGTFPEYPNEEEGGSAVIFSNKTPEQVIEDIIAAQEEEEKSKKKKKKEEKE 362

  Fly   372 TKDK--SKSPARSGDLNVNENQDEEVSFQPAPSVCLPDIRAEIDLFNDTWRDKDETGVLSQAAYE 434
            .|.|  .|...|.........::|:..::.:||:.|..:.....|:.|.|.:|||:....|....
  Rat   363 NKGKKVKKEKERKTVTKEKAAKEEDEEWKMSPSLFLQLMEEGNSLYKDMWMNKDESWNFPQDYDP 427

  Fly   435 DMIYSDKYQEVELEFRRAVDDVMRQEIELLQTAVGKKV------KKSSKKTR-RSGKKSKK-KKE 491
            :::..:|.:|:|:|.|..||::||||::.|:.||.:::      ||..|:.: |.|::.|: ||:
  Rat   428 ELVKEEKRKELEMEIRVQVDELMRQELKNLKLAVNREIEPQPRLKKGKKQNKGRKGRRGKRGKKD 492

  Fly   492 KDLTPDRTTESLYEELVTNGIIRKYPELRLKQFLGDKALTA----RIGTNPSPG--DIRQILTEY 550
            ||||.|||.||||:|||..|::.:..:::|..::|:.:...    ::...|.|.  |:||::|.|
  Rat   493 KDLTADRTIESLYQELVEEGLLIQALKVKLSDYIGEYSYLGTTLRQVAIEPMPSLLDVRQLITLY 557

  Fly   551 CILPLGSDAIHNCTPLIRSILLAGPKGSGKKALLHAICTEVGAVLFDLTPANIVGKYPGKSGLIM 615
            .||||||..:|...||::|:|||||.|.|||.|:||||||.||.||:|:.:||.||||||:||.|
  Rat   558 GILPLGSAEVHERAPLVKSLLLAGPPGVGKKMLVHAICTETGANLFNLSSSNIAGKYPGKTGLQM 622

  Fly   616 LIHLVLKVSRLLQPAVIFMGDAERPFMKKIPKTD-RTDPKRLKKDLPKLIKNIAPEDRVVFIGTS 679
            :||||.||:|.|||:|:::.|.|:.|.||:|:.: |.:||||||.||||:|.:.|:||::.:||:
  Rat   623 MIHLVFKVARQLQPSVVWIQDTEKTFYKKVPQAEKRNEPKRLKKYLPKLLKLLRPDDRILIVGTT 687

  Fly   680 NLPWEADQKLLQSVYNRFIYIPRPDYGAMSHAWKTLLHDYSGGISN-LDTSAMAKISDGYTIGSI 743
            :.|::|:.:....||.:.|.:|||||.:....||.::....|.::| |:.|.::|::||:|.|.|
  Rat   688 HRPFDAELQSFCRVYQKIILVPRPDYASRYVLWKQIILRNGGEVTNALNISCLSKVTDGFTQGQI 752

  Fly   744 DACLKEVMTCKRKLQLRTQPLTNAELINVLCSRDPVYREEEEAFESWWSKTPLGRRRQRFLELEE 808
            ...:|||:|.:|..|...:|||..|.|.::.:.:||||||||:|::|::||||||:  |.|.|..
  Rat   753 VHVIKEVLTERRIRQQAHKPLTAIEFITMMTNMNPVYREEEESFKNWYAKTPLGRK--RVLSLTV 815

  Fly   809 ERLLEEQAQAAKQGNGNKKK 828
            ....|::....|:|...|||
  Rat   816 GGGKEKEKDKGKKGKKGKKK 835

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG16789	NP_649910.3	DUF5401	<131..>307	CDD:375164	64/184 (35%)
		SpoVK	443..773	CDD:440232	154/345 (45%)
		P-loop containing Nucleoside Triphosphate Hydrolases	542..700	CDD:476819	86/158 (54%)
Iqca1	NP_001418200.1	CDC48	<420..758	CDD:273521	145/337 (43%)
		P-loop containing Nucleoside Triphosphate Hydrolases	549..708	CDD:476819	86/158 (54%)