Protein Alignment CG16789 and Nvl

DIOPT Version :10

• Sequence 1: NP_649910.3
• Gene: CG16789 / 41154
• FlyBaseID: FBgn0037712
• Length: 831
• Species: Drosophila melanogaster
• Sequence 2: NP_001099450.1
• Gene: Nvl / 289323
• RGDID: 1311270
• Length: 855
• Species: Rattus norvegicus
• Alignment Length: 674
• Identity: 129/674 - (19%)
• Similarity: 223/674 - (33%)
• Gaps: 208/674 - (30%)

  Fly   223 DSGLLAAMKIQKMWRGHTARRITRRRKMEEMILIGMLPPPPAVVKERAEKLEKLQHNEKRYQAQA 287
            |:|:||: .:|:|:.....||                                 :.|..|.|.:.
  Rat    31 DTGILAS-DLQRMYSVDYGRR---------------------------------KRNAFRIQVEK 61

  Fly   288 FYGKEFEERQNALKEEIRAKHGAS-MKEDIADEIRAWVKDCYDKTGKLPDFPSED---------- 341
            .:.....|:::...:|:...|.|. .::|..||   :.:...|....:.|:|...
  Rat    62 VFNIISSEKEHKNLKELEDGHLAKRARQDEDDE---YTESYSDDDSNMEDYPDPQSANHMNSSLL 123

  Fly   342 ----QGGSLHIFSRPGTESEHSRSSA---RSSKESRKTKDKSKSPARSGDLNVNENQDEEVSFQP 399
                :|.|..:.:.|..|.....:|:   .|..:|...|..::.|.....::......:|
  Rat   124 SLYRKGNSDSVSTTPKLEQREDATSSPLLSSKTDSMPLKTPAREPEGGWFIDKTPGGQKE----- 183

  Fly   400 APSVCLPDIRAEIDLFNDTWRDKDETGVLSQAAYEDMIYSDKYQEVELEFRRAVDDVMRQEIELL 464
                .||     :||.:|....|.:...:.......::.|||
  Rat   184 ----SLP-----LDLSDDQSNCKKQDPGIQNLKDSSLLESDK----------------------- 216

  Fly   465 QTAVGKKVKKSSKKTRRSGKKSKKKKEKDLTPDRTTESLYEELVTNGIIRKYPELRLKQFLGDKA 529
                       .:|:|..||.:|:|.|.....|...|::.::...    .|..||::.....:.
  Rat   217 -----------KRKSRAKGKGNKRKTEGLQEADGEIEAILQKRAK----AKSTELQISSVKFED- 265

  Fly   530 LTARIGTNPSPGDIRQILTEYCILPLGSDAIHNCTPLI---------RSILLAGPKGSGKKALLH 585
                :|.|.:      .|.|.|.:     .||...|.:         |.:||.||.|.||..|.|
  Rat   266 ----VGGNDA------TLKEVCKM-----LIHMRHPEVYQHLGVVPPRGVLLHGPPGCGKTLLAH 315

  Fly   586 AICTEVGAVLFDLTPANIVGKYPGKSGLIMLIHLVLKVSRLLQPAVIFMGDAERPFMKKIPKTDR 650
            ||..|:...:..:....||....|:|        ..|:..|...||     :..|.:..|.:.|.
  Rat   316 AIAGELDLPILKVAAPEIVSGVSGES--------EQKLRDLFDQAV-----SNAPCIVFIDEIDA 367

  Fly   651 TDPKR--LKKDLPKLI-----------KNIAPEDRVVFIGTSNLPWEADQKLLQS-VYNRFIYIP 701
            ..|||  ..||:.:.|           .|:|...||:.:|.:|.|...|..|.:: .::|.:.:.
  Rat   368 ITPKREVASKDMERRIVAQLLTCMDDLNNVAATARVLVVGATNRPDSLDPALRRAGRFDREVCLG 432

  Fly   702 RPDYGAMSHAWKTLLHDYSGGISNLDTSAMAKISDGYTIGSIDACLKEVMTC-------KRKLQL 759
            .||..:.....:||....... ...:.|.:|.::.|:....:.|..:|...|       :|:.|.
  Rat   433 IPDEASRERILQTLCRKLRLP-ETFNFSHLAHLTPGFVGADLMALCREAAVCAVHRVLMRRQEQQ 496

  Fly   760 RTQPLTNA------------------------ELINVLCSRDPVYREEEEAFESWWSKTPLGRRR 800
            ||:|.|..                        .|:.:|..:||:..|:.:..
  Rat   497 RTEPETGGLPSDGEQGRSLGAEPPSETQDELQRLLGLLRDQDPISEEQMQGL------------- 548

  Fly   801 QRFLELEE--ERLLEEQAQAAKQG 822
              .|||.:  ..|.|.|..|.::|
  Rat   549 --CLELNDFIVALSEVQPSAKREG 570

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG16789	NP_649910.3	DUF5401	<131..>307	CDD:375164	13/83 (16%)
		SpoVK	443..773	CDD:440232	77/383 (20%)
		P-loop containing Nucleoside Triphosphate Hydrolases	542..700	CDD:476819	46/180 (26%)
Nvl	NP_001099450.1	Nucleolin_bd	2..71	CDD:465247	12/73 (16%)
		CDC48	<255..855	CDD:273521	79/361 (22%)