Protein Alignment CG16789 and Iqca1l

DIOPT Version :10

• Sequence 1: NP_649910.3
• Gene: CG16789 / 41154
• FlyBaseID: FBgn0037712
• Length: 831
• Species: Drosophila melanogaster
• Sequence 2: NP_808344.3
• Gene: Iqca1l / 231045
• MGIID: 3045319
• Length: 825
• Species: Mus musculus
• Alignment Length: 874
• Identity: 338/874 - (38%)
• Similarity: 487/874 - (55%)
• Gaps: 95/874 - (10%)

  Fly     1 MSSTYFNDIWHQS--------QHECELLSTIDYERQHQDVETTVATMNAAVGSVAADADAKALLQ 57
            ||...:..:|..|        :.|..:|..:. .|:.|..:..::.:
Mouse     1 MSEGTYQRLWEASHVTLEEVLEKEPSVLEPVP-SRERQSFQYRISVL------------------ 46

  Fly    58 SSLYEFYLRYICLSNRLEDVYDNMIQPQKRQLVRKLLDACLGRVVELKHDLVNIDLMEFSYNDEV 122
                  ||.|:.|..|....||.|:|||||:|:|:|||...|||:|||.:||.:||.|....|.|
Mouse    47 ------YLYYLGLLRRFNLAYDQMVQPQKRRLLRRLLDGVAGRVLELKDELVRVDLCETHCLDRV 105

  Fly   123 VERLRLTPMETELRIPRYFLRERQQELEFRKKTMHEILTKLGWLEEHE----LEETVTTEIEAIR 183
            ::.|:|||.:.|:.||:||..|:...::.|::.:.:||.:|..|...|    |..|.     |:.
Mouse   106 LQDLKLTPADLEVPIPKYFQLEQSSAVKARQQMLADILNRLEPLVSQENLRGLSRTA-----ALI 165

  Fly   184 MLQMHERARQGRLRAHFMKEIRILKEKGKS--EERTEKERSDSGLLAAMKIQKMWRGHTARRITR 246
            ::|..||||||||||.||:|||..:|:.:.  |...:|...|.|   |:.|||:|:|:..|:...
Mouse   166 LVQSAERARQGRLRATFMREIRKEEERDRRIWENGQQKFSRDQG---AIVIQKVWKGYLQRKRIE 227

  Fly   247 RRKMEEMILIGMLPPPPAVVKERAEKLEKLQH----NEKRYQAQAFYGKEFEERQNALKEEIRAK 307
            :.:..||..|||||.|     .:..:|..|..    .|.|...|....:||:|......|.:...
Mouse   228 QDRRVEMEFIGMLPSP-----NQTARLNTLNQAFLGEESRRMRQVEKEEEFQEAIGKTYESLTET 287

  Fly   308 HGASMKEDIADEIRAWVKDCYDKTGKLPDFPSEDQGGSLHIFSRPGTE---------SEHSRSSA 363
            .|..|||.:.|:||.|..:|:..||:.||:|.|..|||..||:....|         ::.||...
Mouse   288 EGPDMKERMKDQIRQWFIECHALTGRFPDYPDEASGGSYLIFADKTPEQVRLDLEAQAQESRKKD 352

  Fly   364 RSSKESRKTKDKSKSPARSGDLNVNE-NQDEEVSFQPAPSVCLPDIRAEIDLFNDTWRDKDETGV 427
            :..||..|.|:|.|...:...:...: .::.||.|:..||..:|.|.|..:.:...|:.:.:...
Mouse   353 QEKKEKNKEKEKEKKEKKKKKVKEEKVKKEPEVMFRVLPSKSIPVINAGHEEYTSVWKSRYDNKH 417

  Fly   428 LSQAAYEDMIYSDKYQEVELEFRRAVDDVMRQEIELLQTAVGK---KVKKSSKKTRRSGKKS-KK 488
            .||....:.:..:|.::||:|.|..||::||||::.|:.||.:   :..||.||  :.|||| ||
Mouse   418 PSQNFDSETLREEKRKQVEMEIRVQVDELMRQELKNLRLAVDREETRPLKSPKK--KGGKKSGKK 480

  Fly   489 KKEKDLTPDRTTESLYEELVTNGIIRKYPELRLKQFLGD-----KALT-ARIGTNPSPGDIRQIL 547
            ||||||||||:.:||:||||..|:|:|...:.|..::||     ..|| |.....||..||||.:
Mouse   481 KKEKDLTPDRSVDSLFEELVIIGLIKKSALVTLSDYIGDCLYLGSTLTLANKMPMPSLFDIRQNM 545

  Fly   548 TEYCILPLGSDAIHNCTPLIRSILLAGPKGSGKKALLHAICTEVGAVLFDLTPANIVGKYPGKSG 612
            ..|.:|.|||..||...||:|||||.||.|.|||.|:.|:|||.||.||||:|.|::||||||:|
Mouse   546 ALYGVLRLGSHDIHTMAPLVRSILLVGPSGMGKKMLVQAVCTETGANLFDLSPDNLMGKYPGKNG 610

  Fly   613 LIMLIHLVLKVSRLLQPAVIFMGDAERPFMKKIPKTDRT-DPKRLKKDLPKLIKNIAPEDRVVFI 676
            ..:|:|:|.||:|||||:||::|:.|:.|.||:||.:|| ||||:||||.:..|.::|.|||:.|
Mouse   611 AQLLVHIVFKVARLLQPSVIWIGNTEKTFYKKVPKEERTMDPKRIKKDLMRATKQLSPGDRVMLI 675

  Fly   677 GTSNLPWEADQKLLQSVYNRFIYIPRPDYGAMSHAWKTLLHDYSGGI---SNLDTSAMAKISDGY 738
            ||:..|..|:.|.|...|.|.::||||||.:....||.::.....|:   |:||.||:|::||||
Mouse   676 GTTERPQLAEMKGLCRFYERILFIPRPDYASRYVLWKRMIESQGRGVQLTSSLDVSALARVSDGY 740

  Fly   739 TIGSIDACLKEVMTCKRKLQLRTQPLTNAELINVLCSRDPVYREEEEAFESWWSKTPLGRRRQRF 803
            |...|...::.|:|.:|.|||..:||..:|.:..|...|||||||||:.:.|:.|||||::..:|
Mouse   741 TPSHILQSIQSVLTERRLLQLIKKPLVASEFVGHLARLDPVYREEEESLKEWFFKTPLGKKNMKF 805

  Fly   804 ----LELEEERLLEEQAQAAKQGNGNKKK 828
                ||.||.||.:|:         .|||
Mouse   806 TKDQLEAEEARLTKEK---------KKKK 825

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG16789	NP_649910.3	DUF5401	<131..>307	CDD:375164	60/185 (32%)
		SpoVK	443..773	CDD:440232	167/343 (49%)
		P-loop containing Nucleoside Triphosphate Hydrolases	542..700	CDD:476819	87/158 (55%)
Iqca1l	NP_808344.3	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	344..378		8/33 (24%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	459..487		15/29 (52%)
		P-loop containing Nucleoside Triphosphate Hydrolases	540..699	CDD:476819	87/158 (55%)