Protein Alignment CG16789 and cdc-48.2

DIOPT Version :10

• Sequence 1: NP_649910.3
• Gene: CG16789 / 41154
• FlyBaseID: FBgn0037712
• Length: 831
• Species: Drosophila melanogaster
• Sequence 2: NP_495705.1
• Gene: cdc-48.2 / 174309
• WormBaseID: WBGene00008053
• Length: 810
• Species: Caenorhabditis elegans
• Alignment Length: 649
• Identity: 126/649 - (19%)
• Similarity: 218/649 - (33%)
• Gaps: 198/649 - (30%)

  Fly   238 GHTARRITRRRKMEEMIL--------IGMLPP-------PP---------AVVKERA-------- 270
            |...:::.:.::|.|:.|        ||:.||       ||         ||..|..
 Worm   212 GGVRKQLAQIKEMVELPLRHPQLFKAIGVKPPRGILLFGPPGTGKTLIARAVANETGAFFFLING 276

  Fly   271 -EKLEKLQHNEKRYQAQAFYGKE-------FEERQNALKEEIRAKHGASMKEDIA------DEIR 321
             |.:.|:....:....:||...|       |.:..:|:..:....||...|..::      |.::
 Worm   277 PEIMSKMSGESESNLRKAFAECEKNSPAILFIDEIDAIAPKREKAHGEVEKRIVSQLLTLMDGLK 341

  Fly   322 AWVKDCYDKTGKLPDFPSEDQGGSLHIFSRPGTESEHSRSSARSSKESRKTKDKSKSPARSGDLN 386
            .............|:  |.|  |:|..|.|...|.:.....|....|..:...|
 Worm   342 TRAHVVVIAATNRPN--SID--GALRRFGRFDREIDIGIPDAVGRLEILRIHTK----------- 391

  Fly   387 VNENQDEEVSFQPAPSVCLPDIRAEIDLFNDTWRDKDETGVLSQAAYEDMIYSDKYQEVELEFRR 451
             |....|:|..:...:.|...:.|::            ..:.|:||.:.:  .:|.:.::||
 Worm   392 -NMKLGEDVDLEQVANECHGFVGADL------------ASLCSEAAIQQI--REKMELIDLE--- 438

  Fly   452 AVDDVMRQEI--------ELLQTAVGKKVKKSSKKTRRSGKKSKKKKEKDLTPDRTTESLYEELV 508
              ||.:..|:        |..:.|:|   |.|....|.:..::......|:...:..:...:|||
 Worm   439 --DDTIDAEVLNSLAVTMENFRFAMG---KSSPSALREAVVETPNTTWSDIGGLQNVKRELQELV 498

  Fly   509 TNGIIRKYPELRLKQFLGDKALTARIGTNPSPGDIRQILTEYCILPLGSDAIHNCTPLIRSILLA 573
                  :||....:::|       :.|..||                            |.:|..
 Worm   499 ------QYPVEHPEKYL-------KFGMQPS----------------------------RGVLFY 522

  Fly   574 GPKGSGKKALLHAICTEVGAVLFDLTPANIVGKYPGKSGLIMLIHLVLKVSRLLQPAVIFM---- 634
            ||.|.||..|..||..|..|....:....::..:.|:|.  ..:..|...:|...|.|:|.
 Worm   523 GPPGCGKTLLAKAIANECQANFISIKGPELLTMWFGESE--ANVRDVFDKARAAAPCVLFFDELD 585

  Fly   635 --------------GDAERPFMKKIPKTDRTDPKRLKKDLPKLIKNIAPEDRVVFIGTSNLPWEA 685
                          |.|:|...:.:.:.|..:.|:                .|..||.:|.|...
 Worm   586 SIAKARGGSVGDAGGAADRVINQVLTEMDGMNAKK----------------NVFIIGATNRPDII 634

  Fly   686 DQKLLQ-SVYNRFIYIPRPDYGAMSHAWKTLLHDYSGGISNLDTSAMAKISDGYTIGSIDACLKE 749
            |..:|: ...::.||||.||..:....:|..|.. :...::||.:.:||    .|:|...|.|.|
 Worm   635 DPAVLRPGRLDQLIYIPLPDEASRLQIFKASLRK-TPLSADLDLNFLAK----NTVGFSGADLTE 694

  Fly   750 VMTCKRKLQLRTQPLTNAELINVLCSRDPVYREEEEAFESWWSKTPLGRRRQRFLELEEERLLE 813
            :  |:|..:|..:.....|:           |:|:|..:          |..|..||.|:.|.:
 Worm   695 I--CQRACKLAIRESIEREI-----------RQEKERQD----------RSARGEELMEDELAD 735

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG16789	NP_649910.3	DUF5401	<131..>307	CDD:375164	20/108 (19%)
		SpoVK	443..773	CDD:440232	73/356 (21%)
		P-loop containing Nucleoside Triphosphate Hydrolases	542..700	CDD:476819	32/176 (18%)
cdc-48.2	NP_495705.1	CDC48	44..773	CDD:273521	126/649 (19%)