Protein Alignment CG16789 and Vcp

DIOPT Version :10

• Sequence 1: NP_649910.3
• Gene: CG16789 / 41154
• FlyBaseID: FBgn0037712
• Length: 831
• Species: Drosophila melanogaster
• Sequence 2: NP_446316.1
• Gene: Vcp / 116643
• RGDID: 621595
• Length: 806
• Species: Rattus norvegicus
• Alignment Length: 466
• Identity: 102/466 - (21%)
• Similarity: 169/466 - (36%)
• Gaps: 107/466 - (22%)

  Fly   377 KSPARSGDLNVNE--NQDEEVSFQPAPSVCLPDIRAEIDLF-NDTWRDKDETGVLSQAAYEDMIY 438
            |...|...|.|:|  |:|..|.....|.:      .|:.|| .||...|   |...:.|...::.
  Rat    18 KQKNRPNRLIVDEAINEDNSVVSLSQPKM------DELQLFRGDTVLLK---GKKRREAVCIVLS 73

  Fly   439 SDKYQEVELEFRRAVDDVMRQEIELLQTAVGKKVKKSSKKTRRSGKKSKKKKEKDLTPDRTTESL 503
            .|...:.::...|.|.:.:|       ..:|..:........:.||:.......| |.:..|.:|
  Rat    74 DDTCSDEKIRMNRVVRNNLR-------VRLGDVISIQPCPDVKYGKRIHVLPIDD-TVEGITGNL 130

  Fly   504 YEELVTNGIIRKYPELRLKQ-FL---GDKALTAR-IGTNPSPGDIRQILTEYCIL---------- 553
            :|..:....:..|..:|... ||   |.:|:..: :.|:|||         |||:
  Rat   131 FEVYLKPYFLEAYRPIRKGDIFLVRGGMRAVEFKVVETDPSP---------YCIVAPDTVIHCEG 186

  Fly   554 -------------PLGSDAIHNCTPLI-------------------------RSILLAGPKGSGK 580
                         .:|.|.|..|...:                         |.|||.||.|:||
  Rat   187 EPIKREDEEESLNEVGYDDIGGCRKQLAQIKEMVELPLRHPALFKAIGVKPPRGILLYGPPGTGK 251

  Fly   581 KALLHAICTEVGAVLFDLTPANIVGKYPGKSGLIMLIHLVLKVSRLLQPAVIFMG--DAERPFMK 643
            ..:..|:..|.||..|.:....|:.|..|:|.  ..:....:.:....||:||:.  ||..|
  Rat   252 TLIARAVANETGAFFFLINGPEIMSKLAGESE--SNLRKAFEEAEKNAPAIIFIDELDAIAP--- 311

  Fly   644 KIPKTDRTDPKRLKKDLPKLIKNIAPEDRVVFIGTSNLPWEADQKLLQ-SVYNRFIYIPRPD-YG 706
            |..||.....:|:...|..|:..:.....|:.:..:|.|...|..|.: ..::|.:.|..|| .|
  Rat   312 KREKTHGEVERRIVSQLLTLMDGLKQRAHVIVMAATNRPNSIDPALRRFGRFDREVDIGIPDATG 376

  Fly   707 AMS----HAWKTLLHDYSGGISNLDTSAMAKISDGYTIGSIDA-CLKEVMTCKRK----LQLRTQ 762
            .:.    |.....|.|      ::|...:|..:.|:....:.| |.:..:...||    :.|..:
  Rat   377 RLEILQIHTKNMKLAD------DVDLEQVANETHGHVGADLAALCSEAALQAIRKKMDLIDLEDE 435

  Fly   763 PLTNAELINVL 773
            .: :||::|.|
  Rat   436 TI-DAEVMNSL 445

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG16789	NP_649910.3	DUF5401	<131..>307	CDD:375164
		SpoVK	443..773	CDD:440232	83/395 (21%)
		P-loop containing Nucleoside Triphosphate Hydrolases	542..700	CDD:476819	44/208 (21%)
Vcp	NP_446316.1	CDC48	25..764	CDD:273521	100/459 (22%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	708..727
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	768..806
		Interaction with UBXN6. /evidence=ECO:0000250	797..806
		PIM motif. /evidence=ECO:0000250|UniProtKB:P55072	802..806