Protein Alignment Vps45 and stxbp1

DIOPT Version :9

• Sequence 1: NP_649909.1
• Gene: Vps45 / 41153
• FlyBaseID: FBgn0261049
• Length: 574
• Species: Drosophila melanogaster
• Sequence 2: NP_001072521.1
• Gene: stxbp1 / 779976
• XenbaseID: XB-GENE-945143
• Length: 604
• Species: Xenopus tropicalis
• Alignment Length: 590
• Identity: 120/590 - (20%)
• Similarity: 257/590 - (43%)
• Gaps: 97/590 - (16%)

  Fly    23 KIILLDKETTSIISMAFSQSDMLQREVYLFERLDSGRSNERLKYLKCIVFIRPTKQNIQLLANEL 87
            |::::|:.:..::|.....:|::...:.:.|  |..:..|.:..|:.:..|.|:::::..|.::.
 Frog    29 KVLVVDQLSMRMLSSCCKMTDIMTEGITIVE--DINKRREPIPSLEAVYLITPSEKSVHSLISDF 91

  Fly    88 RNP---KYSAYYIYFSNIIPRTDIKYLAECDESESVREVKELYADYLCVNPNLFSLGIPNCMANL 149
            ::|   ||.|.:::|::..|.|....|.:...|:.::.:.|:...:|.....:|||..|:...:.
 Frog    92 KDPPSSKYRAAHVFFTDSCPDTLFNELVKSRTSKMIKTLTEINIAFLPYESQVFSLDYPDSFHSF 156

  Fly   150 NWLP-------DALNRSMQGITAVLLSLKLNPVIRYRAGSQAAQLLAKLIYEQITKESSLFDFRS 207
             :.|       ..|.|..:.|..:..:||..|.:|||...:...:|::||.:::....:......
 Frog   157 -YSPHKAQMKNPILERLAEQIATLCATLKEYPAVRYRGDYKDNAMLSQLIQDKLDAYKADDPTMG 220

  Fly   208 NMDGAAPPLLLVLDRRDDPVTPLLHQWTYQAMVHELLHIKNNRLDLSNCPNVPKDFKELVLSGDQ 272
            .....|...|::|||..||.:|:||:.|:|||.::||.::|:...........:..||::|..|
 Frog   221 EGPDKARSQLIILDRGFDPASPILHELTFQAMSYDLLPVENDVYKYETSGIGDQRMKEVLLDED- 284

  Fly   273 DDFYGNNMYANYGEIGSTIKQLMEEF--QRKANDHKKVESIADMKNFIESYPQFKKMSGTVQKHL 335
            ||.:....:.:..|:...:.:.:::|  .::.|...||.::.|:...::..||::|
 Frog   285 DDLWVTLRHKHIAEVSQEVTRSLKDFSASKRMNTGDKVTTMRDLSQMLKKMPQYQK--------- 340

  Fly   336 CVIGELSALSNKRNLFE------------VSELEQEIACKAEHSAQ-----LQRIKKLIADERVS 383
                |||..|...:|.|            :..:||::|...:...:     ::.|..::.|..||
 Frog   341 ----ELSKYSTHLHLAEDCMKHYQGTVDKLCRVEQDLAMGTDAEGEKIKDPMRAIVPILLDGNVS 401

  Fly   384 IDDALKLVALYALRYERHANCDTSGLLQIIKTRGGRAAIVPSLIEYAGTHVRQGDLF-NMVR--- 444
            ..|.::::.||                 |....|.....:..||::|.......::. ||..
 Frog   402 TYDKIRIINLY-----------------IFLKNGITEENLNKLIQHAQIPPEDSEIITNMAHLGV 449

  Fly   445 --ITDAVKLTRNLIKGLKGV-ENVF--TQHTPLLKETLEDVFKGRELDPLFPAI----------- 493
              |||:....|:.....:.: |..:  ::.||::|:.:||....:.....:|.|
 Frog   450 PIITDSTLRRRSKPDRKERISEQTYQLSRWTPVVKDIMEDTIDDKLDTKHYPYISTRSSASFSTT 514

  Fly   494 -----------NSELVPFRRPPQEVVVFIIGGATYEEALAVHQLN--NAGYKVILGGTTIHNSQS 545
                       |.....:|..|: :::||:||....|....::::  |..::|::|.|.|.....
 Frog   515 AVSARYGHWHKNKAPGEYRAGPR-LIIFILGGVALSEMRCAYEVSQANGKWEVLIGSTHILTPTK 578

  Fly   546 FIQEV 550
            |::::
 Frog   579 FLEDL 583

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Vps45	NP_649909.1	Sec1	23..543	CDD:279352	119/581 (20%)
stxbp1	NP_001072521.1	Sec1	29..576	CDD:366407	119/581 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910