Protein Alignment Vps45 and vps45

DIOPT Version :10

• Sequence 1: NP_649909.1
• Gene: Vps45 / 41153
• FlyBaseID: FBgn0261049
• Length: 574
• Species: Drosophila melanogaster
• Sequence 2: NP_001072504.1
• Gene: vps45 / 779959
• XenbaseID: XB-GENE-961682
• Length: 570
• Species: Xenopus tropicalis
• Alignment Length: 578
• Identity: 302/578 - (52%)
• Similarity: 418/578 - (72%)
• Gaps: 20/578 - (3%)

  Fly     1 MNLISGIKLYIEKMCSESGPGMKIILLDKETTSIISMAFSQSDMLQREVYLFERLDSGRSNERLK 65
            ||::..:|.|:.||..:||||||::|:||||||::||.::||::||:|||||||:|| .:.|.:|
 Frog     1 MNVVLAVKQYVSKMIEDSGPGMKVLLMDKETTSVVSMVYTQSEILQKEVYLFERIDS-TNRESMK 64

  Fly    66 YLKCIVFIRPTKQNIQLLANELRNPKYSAYYIYFSNIIPRTDIKYLAECDESESVREVKELYADY 130
            :||.|.|:||||:|::.|..|||.||||.|::||||:|.::|:|.|||.||.|.|.||:|.|.||
 Frog    65 HLKAICFLRPTKENVEYLIKELRRPKYSVYFLYFSNVISKSDVKSLAEADEQEVVAEVQEFYGDY 129

  Fly   131 LCVNPNLFSLGIPNCMANLNWLPDALNRSMQGITAVLLSLKLNPVIRYRAGSQAAQLLAKLIYEQ 195
            :.|||::|||.|..|....||....|.|:.||:||:|||||..|:|||:..|..|:.||:.:.:.
 Frog   130 IAVNPHVFSLNIVGCYQGRNWDAVHLYRTTQGLTALLLSLKKCPMIRYQLSSDMAKRLAEGVKQV 194

  Fly   196 ITKESSLFDFRSNMDGAAPPLLLVLDRRDDPVTPLLHQWTYQAMVHELLHIKNNRLDLSNCPNVP 260
            ||||..||:||..   ..|||||:|||.||.:||||:||||||||||:|.|.|||:|||..|.:.
 Frog   195 ITKEYELFEFRRT---EVPPLLLILDRSDDAITPLLNQWTYQAMVHEMLGINNNRIDLSRVPGIS 256

  Fly   261 KDFKELVLSGDQDDFYGNNMYANYGEIGSTIKQLMEEFQ-RKANDHKKVESIADMKNFIESYPQF 324
            ||.||:|||.:.|:||.||||.|:||||:.||.|||:|| :|....:|:|||:|||.|:|:||||
 Frog   257 KDLKEVVLSAENDEFYANNMYLNFGEIGTNIKNLMEDFQKKKPKGQQKLESISDMKAFVENYPQF 321

  Fly   325 KKMSGTVQKHLCVIGELSALSNKRNLFEVSELEQEIACKAEHSAQLQRIKKLIADERVSIDDALK 389
            |||||||.||:.|:||||.|.::|:|.||||:|||:||:.:||..||.:|:|:.::|::..||.:
 Frog   322 KKMSGTVSKHVTVVGELSRLVSERHLMEVSEVEQELACQNDHSNALQNVKRLLQNQRLAELDATR 386

  Fly   390 LVALYALRYERHANCDTSGLLQIIKTRG---GRAAIVPSLIEYAGTHVRQGDLFNMVRITDAVKL 451
            ||.||||.||||::...|.||..::.||   ....:|.:::||.|..||..|||:.   .|||.:
 Frog   387 LVMLYALHYERHSSNALSSLLNDLRVRGVSEKYRRLVSAVVEYGGKRVRGSDLFSP---KDAVAI 448

  Fly   452 TRNLIKGLKGVENVFTQHTPLLKETLEDVFKGRELDPLFPAINSELVPFRRPPQEVVVFIIGGAT 516
            |:...|||||||||:|||.|.|.:||:.:.||:..|.|:|.:....:  |..||:::||::||||
 Frog   449 TKQFFKGLKGVENVYTQHQPFLLDTLDQLIKGKLKDNLYPYLGPNTL--RDRPQDIIVFMVGGAT 511

  Fly   517 YEEALAVHQLNNA--GYKVILGGTTIHNSQSFIQEVVAA----TSGIQFK-HTKSMIK 567
            ||||.||:.||..  |.:::||||.|||::||::||.:|    .||..:: .:||.::
 Frog   512 YEEAFAVYNLNRTTPGVRIVLGGTAIHNTKSFLEEVQSAGFPGRSGESYQPASKSSVR 569

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Vps45	NP_649909.1	Sec1	23..549	CDD:460020	284/531 (53%)
vps45	NP_001072504.1	Sec1	23..546	CDD:460020	284/531 (53%)