Protein Alignment Vps45 and stxbp1a

DIOPT Version :9

• Sequence 1: NP_649909.1
• Gene: Vps45 / 41153
• FlyBaseID: FBgn0261049
• Length: 574
• Species: Drosophila melanogaster
• Sequence 2: XP_005161170.1
• Gene: stxbp1a / 574003
• ZFINID: ZDB-GENE-050626-106
• Length: 603
• Species: Danio rerio
• Alignment Length: 595
• Identity: 129/595 - (21%)
• Similarity: 257/595 - (43%)
• Gaps: 108/595 - (18%)

  Fly    23 KIILLDKETTSIISMAFSQSDMLQREVYLFERLDSGRSNERLKYLKCIVFIRPTKQNIQLLANEL 87
            |.:::|:.:..::|.....:|::...:.:.|  |..:..|.|..|:.|..|.||.:::|.|.|:.
Zfish    29 KALIVDQLSMRMLSSCCKMTDIMTEGITIVE--DIMKRREPLPSLEAIYLITPTDKSVQTLINDF 91

  Fly    88 RNP---KYSAYYIYFSNIIPRTDIKYLAECDESESVREVKELYADYLCVNPNLFSLGIPNCMANL 149
            ::|   ||...:::|::..|......:.:...|::::.:.|:...:|.....:|||..|:...:.
Zfish    92 KDPHSAKYKGAHVFFTDSCPDPLFNEVVKSRASKTIKTLNEINIAFLPYESQVFSLDNPDAFQSF 156

  Fly   150 NWLP-------DALNRSMQGITAVLLSLKLNPVIRYRAGSQAAQLLAKLIYEQITKESSLFDFRS 207
             :.|       ..:.|..:.:..:..:||..|.:|||...:....||:|:.:::....:......
Zfish   157 -YSPHKTQLKNPVMERLAEQLATLCATLKEYPAVRYRGEYKDNATLAQLLQDKLDAYKADDPTMG 220

  Fly   208 NMDGAAPPLLLVLDRRDDPVTPLLHQWTYQAMVHELLHIKNN--RLDLSNCPNVPKDFKELVLSG 270
            .....|...|::|||..|||:|:||:.|:|||.::||.|:|:  :.|.|...:..:  ||::|..
Zfish   221 EGPDKARSQLIILDRGFDPVSPVLHELTFQAMAYDLLPIENDVYKYDTSGIGDSRE--KEVLLHE 283

  Fly   271 DQDDFYGNNMYANYGEIGSTIKQLMEEF--QRKANDHKKVESIADMKNFIESYPQFKKMSGTVQK 333
            | ||.:....:.:..|:...:.:.::||  .::.|..:|. ::.|:...::..||::|
Zfish   284 D-DDLWVALRHKHIAEVSQEVTRSLKEFSASKRMNTGEKT-TMRDLSQMLKKMPQYQK------- 339

  Fly   334 HLCVIGELSALSNKRNLFE------------VSELEQEIACKAEHSAQ-----LQRIKKLIADER 381
                  |||..|....|.|            :..:||::|...:...:     ::.|..::.|..
Zfish   340 ------ELSKYSTHLQLAEDCMKHYQGTVDKLCRVEQDLAMGTDAEGEKIKDPMRAIVPILLDAN 398

  Fly   382 VSIDDALKLVALYALRYERHANCDTSGLLQIIKTRGGRAAIVPSLIEYAGTHVRQGDLF-NMVR- 444
            |:..|.::::.||                 |....|.....:..||::|.......::. ||..
Zfish   399 VTTYDKIRIILLY-----------------IFLKNGITEENLNKLIQHAQIPPEDSEIITNMAHL 446

  Fly   445 ----ITDAVKLTRNLIKGLKGVENV------FTQHTPLLKETLEDVFKGRELDPLFPAI------ 493
                |||:. |.|.  |.:...|.|      .::.|||:|:.:||....:.....:|.|
Zfish   447 GVPIITDST-LRRG--KKMDRKERVSEQTYQLSRWTPLIKDIMEDAIDDKLDTKHYPYISTRSSS 508

  Fly   494 ----------------NSELVPFRRPPQEVVVFIIGGATYEEALAVHQLN--NAGYKVILGGTTI 540
                            |.....:|..|: ::|||||||::.|....:::.  |..::.|:|.|..
Zfish   509 SFSTSAVSARYGHWHKNKTPGEYRTGPR-IMVFIIGGASFSEMRCAYEVTQANGKWEAIVGSTHS 572

  Fly   541 HNSQSFIQEV 550
            .....|:.::
Zfish   573 LTPTKFLMDL 582

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Vps45	NP_649909.1	Sec1	23..543	CDD:279352	128/586 (22%)
stxbp1a	XP_005161170.1	Sec1	29..575	CDD:279352	128/586 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5158
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810