Protein Alignment Vps45 and stxbp1b

DIOPT Version :9

• Sequence 1: NP_649909.1
• Gene: Vps45 / 41153
• FlyBaseID: FBgn0261049
• Length: 574
• Species: Drosophila melanogaster
• Sequence 2: NP_001082845.1
• Gene: stxbp1b / 557717
• ZFINID: ZDB-GENE-060531-166
• Length: 605
• Species: Danio rerio
• Alignment Length: 625
• Identity: 138/625 - (22%)
• Similarity: 267/625 - (42%)
• Gaps: 153/625 - (24%)

  Fly    23 KIILLDKETTSIISMAFSQSDMLQREVYLFERLDSGRSNERLKYLKCIVFIRPTKQNIQLLANEL 87
            |::::||.:..::|.....:|::...:.:.|  |..:..|.|..::.|..|.|:.::::.|.|:.
Zfish    29 KVLVVDKLSMRMVSSCCKMTDIMSEGITIVE--DITKKREPLPTMEAIFLITPSDESVEGLINDF 91

  Fly    88 ---RNPKYSAYYIYFSNIIPRTDIKYLAECDESESVREVKELYADYLCVNPNLFSLGIPNCMANL 149
               |||.|...:::|::.||.:....|::...|:|::.:.|::..:|.....:||:...:...:.
Zfish    92 RDPRNPIYRGAHVFFTDAIPDSLFNLLSKSRASKSIKTLTEIHIAFLPYESQVFSVDKSDAFQDF 156

  Fly   150 NWLP-------DALNRSMQGITAVLLSLKLNPVIRYRAGSQAAQLLAKLIYEQITKESSLFDFRS 207
             :.|       ..|.|..:.|..:..:||..|.:|||...:...:||:::.::
Zfish   157 -YSPFKADVKNQVLERLAEQIATLCATLKEYPAVRYRGEYKDNAVLAQMLQDK------------ 208

  Fly   208 NMDG-------------AAPPLLLVLDRRDDPVTPLLHQWTYQAMVHELLHIKNNRLDLSNCPNV 259
             :||             .|...||:|||..|||:||||:.|:|||.::||.|:|:..........
Zfish   209 -LDGYKADDPTLGEGPDKARSQLLILDRGFDPVSPLLHELTFQAMAYDLLPIENDVYMYETSGMG 272

  Fly   260 PKDFKELVLSGDQDDFYGNNMYANYGEIGSTIKQLMEEF--QRKANDHKKVESIADMKNFIESYP 322
            ....||::|..| ||.:....:.:..|:.:.:.:.:::|  .:|.|..:|. ::.::...::..|
Zfish   273 DTRMKEVLLDED-DDLWMTLRHKHIAEVSTAVTKSLKDFSASKKMNTGEKT-TMKELSQMLKKMP 335

  Fly   323 QFKKMSGTVQKHLCVIGELSALSNKRNLFE------------VSELEQEIACKAEHSAQ-----L 370
            |::|             |||..|...:|.|            :..:||::|...:...:     :
Zfish   336 QYQK-------------ELSKYSTHLHLAEDCMKQYQGTVDKLCRVEQDLAMGTDAEGEKIKDPM 387

  Fly   371 QRIKKLIADERVSIDDALKLVALYALRYERHANCDTSGLLQIIKTRGGRAAIVPSLIEYAGTHVR 435
            :.|..::.|..|:|.|.::::.||                 |....|.....:..|:::|.....
Zfish   388 RAIVPILLDATVTIMDKIRIILLY-----------------IFLKNGVSEENLCKLLQHAQIPPE 435

  Fly   436 QGDLF-NM----VRITDAVKLTRNLIKGLKG--VENV------FTQHTPLLKETLEDVFKGRELD 487
            ..|:. ||    |.|......||   ||.|.  .|.:      .::.|||:|:.:||..:.: ||
Zfish   436 DSDIISNMAHMGVPIISEQATTR---KGKKSDRKERISEQTYQLSRWTPLVKDIMEDAIEDK-LD 496

  Fly   488 P-LFPAINSELVPFR---------------RPPQE------VVVFIIGGATYEEALAVHQLN--N 528
            | .:|.|::..|..:               :.|.|      ::|||:||.||.|...|:::.  |
Zfish   497 PKQYPYISTRTVSSKTTTATSARYGNWHKNKSPGEIRNGPRIIVFIVGGVTYSEMRCVYEVTQAN 561

  Fly   529 AGYKVILGGTTIHNSQSFIQEVVAATSGIQFKHTKSMIKY 568
            ..::.::|.|                      ||.:.:||
Zfish   562 GKWEALIGST----------------------HTITPVKY 579

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Vps45	NP_649909.1	Sec1	23..543	CDD:279352	134/598 (22%)
stxbp1b	NP_001082845.1	Sec1	29..576	CDD:279352	136/620 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5158
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810