Protein Alignment Vps45 and stxbp3

DIOPT Version :9

• Sequence 1: NP_649909.1
• Gene: Vps45 / 41153
• FlyBaseID: FBgn0261049
• Length: 574
• Species: Drosophila melanogaster
• Sequence 2: NP_001015972.1
• Gene: stxbp3 / 548726
• XenbaseID: XB-GENE-963836
• Length: 589
• Species: Xenopus tropicalis
• Alignment Length: 597
• Identity: 135/597 - (22%)
• Similarity: 265/597 - (44%)
• Gaps: 90/597 - (15%)

  Fly     7 IKLYIEKMCSESGPGMKIILLDKETTSIISMAFSQSDMLQREVYLFERLDSGRSNERLKYLKCIV 71
            ||..:...| ..|...||:|||..||.:::.....:|:||..:.:.|  |..:..:.::::|.|.
 Frog    17 IKTEVLDDC-RKGDEWKILLLDHFTTKLLTSCCKMTDLLQEGITVVE--DLFKKRQPVEHMKAIY 78

  Fly    72 FIRPTKQNIQLLANELRN---PKYSAYYIYFSNIIPRTDIKYLAECDESESVREVKELYADYLCV 133
            ||.|.::::..|.|:..:   .||.|.|:|||::.|.:....|..| ..::::..||:...:...
 Frog    79 FISPNEKSVDCLVNDFNSKSASKYKAAYVYFSDVCPDSLFNKLKSC-HPKTIKRCKEISISFFPK 142

  Fly   134 NPNLFSLGIPNCMANLNWLPD-------ALNRSMQGITAVLLSLKLNPVIRYRAGS-QAAQLLAK 190
            ...:|.|.:|... :|.:.||       |:....|.|..:..:|:.||.:||:... ..|:.||.
 Frog   143 ESQVFLLNVPKAF-HLLYSPDKAVDKETAIQTIAQQIVTLCATLEENPGVRYKKEPLDNAEELAN 206

  Fly   191 LIYEQITKESSLFDFRSNMDGAAPPLLLVLDRRDDPVTPLLHQWTYQAMVHELLHIKNNRLDLSN 255
            |:.||:.:...: |.:..........||::||..||.:.:||:.|:||||::||.|:|:......
 Frog   207 LVEEQLVQYYKM-DEKDQFKAKTQSQLLIVDRGFDPFSTILHELTFQAMVYDLLPIENDIYKYRT 270

  Fly   256 CPNVPKDFKELVLSGDQDDFYGNNMYANYGEIGSTIKQLMEEFQRKANDHKKVESIADMKNFIES 320
            ...:.|| ||..|. :.|:.:....:.:...:...|.:|::|......:.:...||:.:.:.::.
 Frog   271 ESALAKD-KEARLD-ESDELWVKIRHKHIANVLEEIPKLVKEISSSKKETEGNISISKLADIMKK 333

  Fly   321 YPQFKKMSGTVQKHLCVIGELSALSNKRNLFEVSELEQEIACKAEHSAQLQRIK---KLIADERV 382
            .|..:|..|....||. :.|......:..|.::.:.||::|..::  |:.|::|   :::....:
 Frog   334 MPHIRKQIGKQTLHLS-LAEDCMQKFRGRLEKLCKAEQDLALGSD--AEGQKVKDHMRVLLPILI 395

  Fly   383 SID----DALKLVALYALRYERHANCDTSGLLQIIKTRGGRAAIVPSLIEYAGTHVRQGDL---F 440
            |.|    |.::.:.||.......:..:...|:...|..||                  ||:   :
 Frog   396 SNDLDNYDKIRAILLYIFVENGTSQENLDRLITHAKIEGG------------------GDVLKNW 442

  Fly   441 NMVRITDAVKLT-RNLIKGLKGVENVF--TQHTPLLKETLEDVFKGRELDPLFPAINSELVPF-- 500
            ..:.:....|.| |...:..:..|..|  ::.||::|:.:||..:.:        ::|:..|:
 Frog   443 KYLGVPIVPKSTQRRPARRDRSKEETFQLSRWTPIIKDVIEDTMENK--------LDSKEWPYCS 499

  Fly   501 -------------------------RRPPQEVVVFIIGGATYEEALAVHQLNNAG--YKVILGGT 538
                                     |:....:::|:|||.||.|....::::.|.  .:||:|.|
 Frog   500 ECPAAWNGSGAVSARQKHNTISRDERKNVSRLIIFVIGGITYSEIRCAYEVSQANKFVQVIIGST 564

  Fly   539 TIHNSQSFIQEV 550
            .|...::.:.:|
 Frog   565 HIITPKTMLDDV 576

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Vps45	NP_649909.1	Sec1	23..543	CDD:279352	130/572 (23%)
stxbp3	NP_001015972.1	Sec1	32..569	CDD:366407	130/572 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910