Protein Alignment Vps45 and stxbp3

DIOPT Version :9

• Sequence 1: NP_649909.1
• Gene: Vps45 / 41153
• FlyBaseID: FBgn0261049
• Length: 574
• Species: Drosophila melanogaster
• Sequence 2: XP_009294850.1
• Gene: stxbp3 / 406780
• ZFINID: ZDB-GENE-040426-2833
• Length: 593
• Species: Danio rerio
• Alignment Length: 588
• Identity: 127/588 - (21%)
• Similarity: 258/588 - (43%)
• Gaps: 103/588 - (17%)

  Fly    24 IILLDKETTSIISMAFSQSDMLQREVYLFERLDSGRSNERLKYLKCIVFIRPTKQNIQLLANELR 88
            |::||..||.::|.....||::...:.:.|.|...|  |.:..:|.|.|:.||.:.|....|:.:
Zfish    30 ILILDDFTTRLLSSCCKMSDLMSEGISVLENLFKNR--EPVPDMKAIYFMAPTVECIDAFINDFK 92

  Fly    89 -NPKYSAYYIYFSNIIP-RTDIKYLAECDESESVREVKELYADYL--------CVNPNLFSLGIP 143
             .|||.|.|::|::..| ....|....|  ::.:::.||:...:|        |.||..|.....
Zfish    93 PKPKYKAAYVFFTDYCPDELFDKMKKNC--AKHIKKCKEINISFLPQEAQVFTCENPEAFKKIYS 155

  Fly   144 NCMANLNWLPDALNRSMQGITAVLLSLKLNPVIRYRAGSQA--AQLLAKLIYEQITKESSLFDFR 206
            ....:..   ..|::....|..:..:|...|.:||:..|..  .::||:|:..::.:...|.:..
Zfish   156 GFSQDRE---KTLDKIADQIVTLCATLDEYPGVRYKRESTPGYGKMLAELVDNKLARHYELDEIT 217

  Fly   207 SNMDGAAPPLLLVLDRRDDPVTPLLHQWTYQAMVHELLHIKNNRLDLSNCPNVPKD--FKELVLS 269
            :..: ..|..||::||..|||:|:||:.|||||.::|:.|.||..:..     .||  .||.:|:
Zfish   218 TKKE-KTPAQLLIVDRAMDPVSPILHELTYQAMAYDLIPINNNIYEYK-----MKDGSKKEALLN 276

  Fly   270 GDQDDFYGNNMYANYGEIGSTIKQLMEEFQRKANDHKKVE---SIADMKNFIESYPQFKKM--SG 329
            .| |:.:....:.:..|:...|.:|:::.....::.::.:   :|..:...::..|.|:|.  ..
Zfish   277 ED-DELWVKLRHRHIAEVTEQIPKLVKDISASRDEKQQGDGKITIGALSQLMKKMPAFRKQVTQK 340

  Fly   330 TVQKHLC--VIGELSALSNKRNLFEVSELEQEIACKAEHSAQLQRIKKLIADERVSIDDALKLVA 392
            ||..||.  ::|..     ::|:.::.:.||::|..|:  |:.|::|           |.::  .
Zfish   341 TVHLHLAEDLMGHY-----QKNVEKLCKAEQDLAVGAD--AEGQKVK-----------DPMR--T 385

  Fly   393 LYALRYERHANCD--TSGLLQIIKTRGGRAAIVPSLIEYAGTHVRQGDLFNM----VRITDAVKL 451
            |..:...:|...|  .:.||.|....|.....:..||:......:.|.:.|.    |.|..:...
Zfish   386 LLPVLLHQHDTTDKIRAVLLYIFSLNGTTTENLNKLIQNVKIEDKDGYIQNWNQLGVPILSSSNS 450

  Fly   452 TRNLIKGLKGVENVF--TQHTPLLKETLEDVFKGRELDPLFPAINSELVPFR------------- 501
            :|.:.:..:..:..:  ::.||::|:.:||..:.:        ::.:..||:
Zfish   451 SRKVARRDRSEQETYNVSRWTPVIKDIMEDAVENK--------LDIKDWPFQSECPSAWNGSRAV 507

  Fly   502 -----------------RPPQEVVVFIIGGATYEEALAVHQLNNA--GYKVILGGTTIHNSQSFI 547
                             :....:::|::||.:|.|....:::.|.  ..:||:|.|.|...:|.:
Zfish   508 RVLSARQKHKGSSPGDMKNGSRLIIFVLGGVSYSEMRCAYEVTNTNKSCEVIIGSTHILTPRSLL 572

  Fly   548 QEV 550
            :::
Zfish   573 EDI 575

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Vps45	NP_649909.1	Sec1	23..543	CDD:279352	126/579 (22%)
stxbp3	XP_009294850.1	Sec1	30..568	CDD:279352	126/579 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5158
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.810