Protein Alignment Vps45 and car

DIOPT Version :9

• Sequence 1: NP_649909.1
• Gene: Vps45 / 41153
• FlyBaseID: FBgn0261049
• Length: 574
• Species: Drosophila melanogaster
• Sequence 2: NP_001259707.1
• Gene: car / 32947
• FlyBaseID: FBgn0000257
• Length: 639
• Species: Drosophila melanogaster
• Alignment Length: 657
• Identity: 136/657 - (20%)
• Similarity: 251/657 - (38%)
• Gaps: 163/657 - (24%)

  Fly     7 IKLYIEKMCSE------SGPGMKIILLDKETTSIISMAFSQSDMLQREVYLFERLDSGRSNERLK 65
            ::|..|..|.|      ...|.|:|:||:.....:       |::.|.....:|      ..||.
  Fly    14 LQLLQEAACRELLQQLDRIEGSKVIVLDETMIGPL-------DLVTRPKLFADR------GIRLL 65

  Fly    66 YLK-----------CIVFIRPTKQNIQLLANELRNPKYSA----YYIYFSNIIPRTDIKYLAECD 115
            .||           .:..:||....::.||..::....:|    |:|.|:   ||.....:::.:
  Fly    66 ALKPELHLPREVANVVYVMRPRVALMEQLAAHVKAGGRAAAGRQYHILFA---PRRSCLCVSQLE 127

  Fly   116 ES---ESVREVKELYADYLCVNPNLFSLGIPNCMANLNWLPDALNRSMQGITAVLLSLKLNPVIR 177
            .|   .|...::||..:||.::.:|.|:.:||...::         |:.|.|:.|
  Fly   128 VSGVLGSFGNIEELAWNYLPLDVDLVSMEMPNAFRDV---------SVDGDTSSL---------- 173

  Fly   178 YRAGSQAAQLLAKLIYEQITK---------------------ESSLFDFRSNMDGAAPPLLLVLD 221
            |:|.....||  :.:|.:|.|                     |.:|:    |.|......|::||
  Fly   174 YQAAVGLVQL--QRLYGRIPKIYGKGEFAHRVWEHAKQLGRDERTLY----NGDKGVVDQLILLD 232

  Fly   222 RRDDPVTPLLHQWTYQAMVHELLHIKNNRLDLSNCPNVPKD-----------------------F 263
            |..|.::||..|.||:.::.|...|:.|:|.|. ..|.|.|                       .
  Fly   233 RSIDLLSPLATQLTYEGLIDEFYGIRQNKLTLP-AENFPSDGALPGGGGSGPRVEESQSLLGDTE 296

  Fly   264 KELVLSGDQDDFYGNNMYANYGEIGSTIKQLMEEFQRKANDHKKVESIADMKNFIES-YPQFKKM 327
            |:.:|....:..|......::.|:...:.:...|...:.:...:.:|:.::|:|:|: .||....
  Fly   297 KKTILLHSGEQLYAELRNKHFNEVTKLLARKAREIHVQMHATSQDKSVQEIKSFVENLLPQLMAQ 361

  Fly   328 SGTVQKHLCVIGELSALSNKRNLFEVSELEQEIACKAEHSAQLQRIKKLIADERVSIDDALKLVA 392
            .....:|..:.|.|....|.....:....|||....|:.......|:.|||. ||.::..|:|:.
  Fly   362 KKATSEHTAIAGLLHEQVNAVRFADDLAAEQEFMVCADIDKPSAYIEDLIAC-RVELNRVLRLIC 425

  Fly   393 LYALRYERHANCDTSG----LL-----QIIKTRGGRAAIVPSLIEYAG-THVR-QGDLFNMVRIT 446
            :     :.||   .||    ||     :::...|....:..|.:|.:| .|:: :...::::|.|
  Fly   426 M-----QCHA---ASGFKEKLLNHYKRELVHVYGLEVLLTISNLEKSGLLHLQTESRAYSVLRKT 482

  Fly   447 DAVKLTRNLIKGLKGVENVFTQHTPLLKETLEDVFK--GREL---------DPLFPAINSELV-- 498
            ..:.:..|:....|.:..|.:.:.||....:|...|  |.:.         .|.|....::||
  Fly   483 LHLTVDDNVEIEPKDISYVHSFYAPLTARIVEHSLKPLGWQTLKSQINNLPGPTFEDFQAQLVGI 547

  Fly   499 ------------PFRRPPQEVVVFIIGGATYEEA-----LAVHQLNNAGYKVILGGTTIHNSQSF 546
                        .....|:.|:|..:||.|:.|.     ||..:.||..:  ::..|.:.|..||
  Fly   548 GGRHTVTTVSEGSLLNVPRVVLVCFVGGCTFAEIAALRFLAAQEDNNVEF--LIATTKVVNKHSF 610

  Fly   547 IQEVVAA 553
            :..::::
  Fly   611 LDSLMSS 617

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Vps45	NP_649909.1	Sec1	23..543	CDD:279352	128/623 (21%)
car	NP_001259707.1	Sec1	36..606	CDD:279352	128/622 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45464245
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5158
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11679
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.840