Protein Alignment Vps45 and T07A9.10

DIOPT Version :9

• Sequence 1: NP_649909.1
• Gene: Vps45 / 41153
• FlyBaseID: FBgn0261049
• Length: 574
• Species: Drosophila melanogaster
• Sequence 2: NP_499918.1
• Gene: T07A9.10 / 176862
• WormBaseID: WBGene00020298
• Length: 562
• Species: Caenorhabditis elegans
• Alignment Length: 597
• Identity: 128/597 - (21%)
• Similarity: 256/597 - (42%)
• Gaps: 143/597 - (23%)

  Fly    24 IILLDKETTSIISMAFSQSDMLQREVYLFERLDSGRSNERLKYLKCIVFIRPTKQNIQLLANELR 88
            :::|||....:::...|.:::.:..|.|.|  |..|:.|.:..:..|..|.|..::|.:|.|:..
 Worm    31 VLVLDKSAMVVVNSCLSLNEVFEEGVTLVE--DLTRNREPMPSMDAIYIISPVAESIDILINDFS 93

  Fly    89 -----NP--KYSAYYIYFSNIIPRTDIKYLAECDE-----SES-----VREVKELYADYLCVNPN 136
                 ||  .|.:.:|:|.:..          |||     |:|     ::.:|||..:...|...
 Worm    94 RKTKFNPGNSYRSAHIFFLDPC----------CDELFEKLSKSPAVKWIKTLKELNLNLKPVESQ 148

  Fly   137 LFSLGIPNCMANLNWLPDALNRSMQGITAVLLSLKLNPVIRYRAG-SQAAQLLAKLIYEQITKES 200
            :|::       |..:..| :.::..||.::..:|.::|.:|:::. :|::::..::       |.
 Worm   149 IFTV-------NSQFRGD-MTKTADGIVSLCATLNIHPTLRFQSDFAQSSEICQRV-------EQ 198

  Fly   201 SLFDFRSNMDGAAPPLLLVLDRRDDPVTPLLHQWTYQAMVHELLHIKNNRLDLSNCPNVPKDFKE 265
            .|.:| .|........|:||||..|.|:||||:.|.||||.::...|:.....:..    .|.||
 Worm   199 KLKEF-GNEGMGTDAELVVLDRSFDLVSPLLHEVTLQAMVVDVTAFKDGVYRYTEA----GDSKE 258

  Fly   266 LVLSGDQDDFYGNNMYANYGEIGSTIKQLMEEFQRKANDHK------KVESIADMKNFIESYPQF 324
            :||. ::|..:.:..:....|:..::.:::::|:   |.:|      |.:|..|....:.:...:
 Worm   259 IVLD-EKDQNWLDLRHKLLPEVMKSVNKMVKDFK---NTNKTEPENIKNQSSKDFSTTVRTLQPY 319

  Fly   325 KKMSGTVQKHLCVIGELSALSNKRNLFEVSELEQEIACKAEHSAQLQRIKKLIADERVS------ 383
            .||...:..::.:..|..: ....:|.::..|||::|  .||:.:..||....|..|:|
 Worm   320 LKMKAKMAAYISLTEECRS-KYFDSLEKIIALEQDMA--VEHTPEHVRITDSQAVGRLSTFILPA 381

  Fly   384 --IDDALKLVALYAL-----RYERHANCDTSGLLQIIKTRGGRAAIVPSLIEYAGTHVRQGDLFN 441
              .:..|:|:.::.|     :.|::.|                     .|:.:  |.:.:.: |.
 Worm   382 IPTETRLRLILIFMLTIGKDKDEQYFN---------------------RLLHH--TDIPESE-FQ 422

  Fly   442 MVRITDAVKLTRNLIKGLKGVENVFTQH---------------TPLLKETLEDVFKGRELD---- 487
            :::        |.||...|..::.| ||               .|.:|..:|:::: |.||
 Worm   423 IIK--------RMLIWRDKTQKSQF-QHRRPPPEDERFIASRWDPKIKNLIEEIYE-RRLDEREF 477

  Fly   488 ---------PLFPAIN----SELVPFRRPPQEVVVFIIGGATYEEALAVHQLN-NAGYKVILGGT 538
                     ...||.:    |.|....|..:::::|::||.||.|....::|: .....||||..
 Worm   478 KVAGKKSTSDFRPAASARYGSGLAGKPREKRKIIIFVVGGITYSEMRVAYELSKKTNTTVILGSD 542

  Fly   539 TIHNSQSFIQEV 550
            .|....||::.:
 Worm   543 EILTPSSFLESL 554

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Vps45	NP_649909.1	Sec1	23..543	CDD:279352	126/588 (21%)
T07A9.10	NP_499918.1	Sec1	31..547	CDD:279352	126/588 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5158
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810