DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG9393 and mtx3

DIOPT Version :9

Sequence 1:	NP_649908.1	Gene:	CG9393 / 41152	FlyBaseID:	FBgn0037710	Length:	327	Species:	Drosophila melanogaster
Sequence 2:	NP_991184.1	Gene:	mtx3 / 402916	ZFINID:	ZDB-GENE-021210-3	Length:	313	Species:	Danio rerio

Alignment Length:	235	Identity:	64/235 - (27%)
Similarity:	103/235 - (43%)	Gaps:	3/235 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 LYVYKGEYGLPSIDFECLRALCLLRFTRCPMDVQTSSNPLRSGAGKLPYLQIGNQKFAGYRQIKR 73
            |..:.|::.|||:..:.|..|...:|....:.|:......|:....:|.:...........||..
Zfish     7 LLCWGGDWDLPSVQTDSLTVLAYAKFAGAELTVKFVDWTWRTITASVPQIHYEGTTVTEPTQILN 71

  Fly    74 VLDLEGYPIDAHLSTKQKHLSTAYANWVFTNLH-AYYHYFLFGEPHNFDTTTRGLYAKRTPFPFN 137
            .|..:.:..|..|:.||...:.||...:...|. |..|.| :.:..|:...||..:...:.||.|
Zfish    72 FLRKQRFNADFELTAKQGADTMAYIALLEEKLRPALLHTF-WVDAENYANLTRPWFTSHSLFPLN 135

  Fly   138 FYYPSSYQREACDVVQVMAGFDVNDKLDKHEGDYLVVNAKKVVNLLSRKLGRKVWFFGDTYSEFD 202
            |:.|......|...:.:.........:.:.||. :...||:.:||||.:||...:|||||.:..|
Zfish   136 FFVPGRQASLALSRILLTKAESPLLNITEVEGK-IYSEAKECLNLLSHRLGNFNFFFGDTPTSLD 199

  Fly   203 AIVYSYLAIIFKIALPNNPLQNHIKGCQNLVNFINRITKD 242
            |.|:.::|.:.|..||:..||.|:....||..|.|.|.|:
Zfish   200 AFVFGHIAPLIKAPLPSGQLQKHLNQLDNLCQFCNTILKN 239

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9393	NP_649908.1	GST_N_Metaxin1_like	8..79	CDD:239376	14/69 (20%)
CG9393	NP_649908.1	GST_C_Metaxin1_3	108..244	CDD:198321	42/135 (31%)
mtx3	NP_991184.1	GST_N_Metaxin1_like	5..77	CDD:239376	14/69 (20%)
		GST_C_Metaxin1_3	105..241	CDD:198321	43/137 (31%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	280..313
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170595152
Domainoid	1	1.000	59	1.000	Domainoid score	I10638
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	125	1.000	Inparanoid score	I4679
OMA	1	1.010	-	-		QHG45845
OrthoDB	1	1.010	-	-		D1472286at2759
OrthoFinder	1	1.000	-	-		FOG0002371
OrthoInspector	1	1.000	-	-		otm26230
orthoMCL	1	0.900	-	-		OOG6_103286
Panther	1	1.100	-	-	LDO	PTHR12289
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2657
SonicParanoid	1	1.000	-	-		X2061
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	13	12.940