Protein Alignment MBD-like and mecp2

DIOPT Version :9

• Sequence 1: NP_001262421.1
• Gene: MBD-like / 41151
• FlyBaseID: FBgn0027950
• Length: 340
• Species: Drosophila melanogaster
• Sequence 2: NP_997901.1
• Gene: mecp2 / 335250
• ZFINID: ZDB-GENE-030131-7190
• Length: 524
• Species: Danio rerio
• Alignment Length: 328
• Identity: 71/328 - (21%)
• Similarity: 92/328 - (28%)
• Gaps: 159/328 - (48%)

  Fly    19 LPKGWQRD-EVRKSGSSANNNASSNNNSSATASSNNNNNKVDVFYYSSPTGKRAEGK-------- 74
            ||:||.|. :.||||.||                    .|.|| |..:|.||....|
Zfish   109 LPQGWTRKLKQRKSGRSA--------------------GKFDV-YLINPEGKAFRSKVELMAYFQ 152

  Fly    75 --------PQDIAIPDF-------------QPGKMPHCALPSPSISLYRCSAMPLPIASGGGNGA 118
                    |.|.   ||             :|.|.|....|                 ||.|.|.
Zfish   153 KVGDTITDPNDF---DFTVTGRGSPSRREKRPPKKPKMVKP-----------------SGRGRGR 197

  Fly   119 TSGSA-------ANALKRKFARSQG---------------GNAAGAAGAA-------------PP 148
            ..||.       ..|:||...:|.|               |...|.|..|             ||
Zfish   198 PKGSGKVRQATEGVAVKRVIEKSPGKLLVKMPFVAPKTEPGAPLGQAPVAKARRGRKRKSEQDPP 262

  Fly   149 A--------------ATASSAATATAASASPSTANRQQQQIELSRALRTDVSLVPPIRQTASIFK 199
            :              :|..:.:.|..|:|:..||..:::.::.|.|        .|:::.|...|
Zfish   263 STPKKRGRKPATVSQSTVGTGSAAAYAAAAILTAEAKKKALKESSA--------KPVQERALPIK 319

  Fly   200 QPVTVIRNHKQDPAKAKNEPKHGTREKPKQLFWEKRLERLRACHDSGEELDDISLPKTIRTVGPN 264
                                |..|||         .||.|.|...|..|..:..|  |..||.|.
Zfish   320 --------------------KRKTRE---------TLEELEASTTSATETFEKRL--TASTVTPT 353

  Fly   265 VNE 267
            ..|
Zfish   354 GEE 356

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
MBD-like	NP_001262421.1	MBD	13..98	CDD:279737	27/108 (25%)
		MBDa	172..241	CDD:293172	12/68 (18%)
		MBD_C	246..338	CDD:290755	7/22 (32%)
mecp2	NP_997901.1	MBD	101..175	CDD:128673	23/89 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4161
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1431783at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.820