DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment MBD-like and phf20l1

DIOPT Version :9

Sequence 1:	NP_001262421.1	Gene:	MBD-like / 41151	FlyBaseID:	FBgn0027950	Length:	340	Species:	Drosophila melanogaster
Sequence 2:	XP_009290756.1	Gene:	phf20l1 / 327626	ZFINID:	ZDB-GENE-030131-5837	Length:	1116	Species:	Danio rerio

Alignment Length:	379	Identity:	79/379 - (20%)
Similarity:	124/379 - (32%)	Gaps:	107/379 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly    20 PKGWQRDEVRKSGSSANNNASSNNNSSATASSNNNNNKVDVFYYSSPTGKRAEGKPQDIAIPDFQ 84
            |:....||..:|.|:.....|.:|..:..|.|..         ....:|:.|.......|.|:..
Zfish   320 PEPSPADEKSQSVSAQKTTPSLSNPPACKARSRR---------LKHDSGESASSCQNTPAAPESS 375

  Fly    85 PGKMPHCALP-----SPSISLYR--------------CSAMP-------LPIASGGGNGATSGSA 123
            |...|...||     :||.|..|              |...|       .|.....|.......:
Zfish   376 PLPSPTQTLPDSTHTAPSSSPQRRRRSQRLATTSDLICPPSPHTRDTATHPTPPPDGPLIADEDS 440

  Fly   124 ANALKRKFARSQGGNAAGAAGAAPPAATASSAATATAASASPSTANRQQQQIELSR--ALRTDVS 186
            :..:|.: |.||           .|.:.:.|.||:||::.:|.|...:...:..|.  ||..:..
Zfish   441 STVVKTE-AISQ-----------KPVSESPSTATSTASAQAPITEKEKMNDVLPSNQAALEGNSP 493

  Fly   187 LVPPIRQTASIFKQP-----------VTVIRNHKQDPAKAKNE---PKHGTREKPK-----QLFW 232
            .|.|    |:|.|.|           ..:|...:.|...|.||   .....:.|.|     :.|.
Zfish   494 AVVP----AAIQKVPSRTPKANKHAREPIINTKRSDDPLAPNECIIDLDHNKFKCKVSGCSKAFR 554

  Fly   233 EKRL--ERLRACHDSGEELD---------------DISLP-KTIRTVGPNVNEQTV-----LQSV 274
            :.:|  ..|:..|::.:|:|               ..|:| .|:..|..|...:||     |.|.
Zfish   555 KAKLLDYHLKYYHNTEKEMDTEVCSPEREGRTRATSASMPTSTLSDVPDNKRRRTVSTSSSLSSQ 619

  Fly   275 ATALHMLNAGV----------HGQSSTKADLTKNAMAFMNPEQPLMHAVIISED 318
            ...|.|.:.|.          ...:|..:|.|:  ::...|....:|..||.:|
Zfish   620 GFMLQMDSGGCVRPSKFCKKKRSSASMSSDSTE--VSLPPPTFDNLHDKIIKKD 671

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
MBD-like	NP_001262421.1	MBD	13..98	CDD:279737	18/82 (22%)
		MBDa	172..241	CDD:293172	19/91 (21%)
		MBD_C	246..338	CDD:290755	22/104 (21%)
phf20l1	XP_009290756.1	MBT	3..68	CDD:327428
		TUDOR	121..165	CDD:119391
		DUF3776	248..323	CDD:315317	1/2 (50%)
		Atrophin-1	<312..510	CDD:331285	46/214 (21%)
		PHD_PHF20L1	823..868	CDD:277103
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4161
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900