DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment MBD-like and Mbd3l1

DIOPT Version :9

Sequence 1:	NP_001262421.1	Gene:	MBD-like / 41151	FlyBaseID:	FBgn0027950	Length:	340	Species:	Drosophila melanogaster
Sequence 2:	NP_001100273.1	Gene:	Mbd3l1 / 300389	RGDID:	1308259	Length:	186	Species:	Rattus norvegicus

Alignment Length:	177	Identity:	53/177 - (29%)
Similarity:	86/177 - (48%)	Gaps:	25/177 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly   171 QQQQIELSRALRTDVSLVPPIRQTASIFKQPVTVIRNHKQDPAKAKNEPKH----GTREKPKQLF 231
            |::|.:.....:..:|...|:|.:...||:|||.|.:|      ..||.::    .|.|||:|..
  Rat     6 QRKQCDCENPSKPCLSTSIPLRMSNYTFKRPVTKITSH------LGNEVRYYQWEETLEKPEQAC 64

  Fly   232 WEKRLERLRACHDSGEELDDISLPKTIRTVGPNVNE--QTVLQSVATALHMLNAGVHGQSSTKAD 294
            |:|||:.|:|...:||.|....|.|.::.:.|...:  .:::|  |.::........|.||
  Rat    65 WQKRLQGLQAYSSAGEILSTSDLSKALKDLTPRDTDAASSIIQ--ANSMDPRPLSTLGSSS---- 123

  Fly   295 LTKNAMAFMNPE---QPLMHAVIISEDDIRKQEDRVGVARRKLQDAL 338
                .:|.|.||   |.|....:::|:||..||.:|.:||.:|..||
  Rat   124 ----HLAKMIPEAGPQILCKEFLVTEEDISIQERKVKIARERLAVAL 166

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
MBD-like	NP_001262421.1	MBD	13..98	CDD:279737
		MBDa	172..241	CDD:293172	23/72 (32%)
		MBD_C	246..338	CDD:290755	26/96 (27%)
Mbd3l1	NP_001100273.1	MBDa	8..74	CDD:406868	23/71 (32%)
Mbd3l1	NP_001100273.1	MBD_C	79..166	CDD:404858	26/96 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166340936
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4161
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1431783at2759
OrthoFinder	1	1.000	-	-		FOG0001638
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	7	6.710