DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment MBD-like and Mbd1

DIOPT Version :9

Sequence 1:	NP_001262421.1	Gene:	MBD-like / 41151	FlyBaseID:	FBgn0027950	Length:	340	Species:	Drosophila melanogaster
Sequence 2:	XP_006254971.1	Gene:	Mbd1 / 291439	RGDID:	1305980	Length:	632	Species:	Rattus norvegicus

Alignment Length:	174	Identity:	42/174 - (24%)
Similarity:	62/174 - (35%)	Gaps:	53/174 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly    15 DCSVLPKGWQRDEV-RKSGSSANNNASSNNNSSATASSNNNNNKVDVFYYSSPTGKRAEGKPQ-- 76
            ||..|..||:|.|. ||||:|...:                    |: ||.||||::...|.:
  Rat     7 DCPALGPGWKRREAFRKSGASCGRS--------------------DI-YYRSPTGEKIRSKIELT 50

  Fly    77 -------DIAIPDFQPGKMPHCALPSPSISLYRCSAMPLPIASGGGNGATSGSAANALK------ 128
                   |:.:.||:.|.:.|   |.|...         |:|........:...|.|.|
  Rat    51 RYLGPACDLTLFDFRQGILCH---PVPKTH---------PLAVPSKKKKKTSKPAKAKKQQVGPQ 103

  Fly   129 ----RKFARSQGGNAAGAAGAAPPAATASSAATATAASASPSTA 168
                ||....:|...|.|....|..|:|.:......::.:|:.|
  Rat   104 RSEVRKETPREGNKVAPATALLPVTASAPAPVPVPVSAPAPAPA 147

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
MBD-like	NP_001262421.1	MBD	13..98	CDD:279737	27/92 (29%)
		MBDa	172..241	CDD:293172
		MBD_C	246..338	CDD:290755
Mbd1	XP_006254971.1	MeCP2_MBD	5..66	CDD:238690	23/79 (29%)
		zf-CXXC	186..233	CDD:251032
		zf-CXXC	235..280	CDD:251032
		zf-CXXC	349..393	CDD:251032
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166340934
Domainoid	1	1.000	49	1.000	Domainoid score	I11479
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1431783at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.850