Protein Alignment MBD-like and Mecp2

DIOPT Version :9

• Sequence 1: NP_001262421.1
• Gene: MBD-like / 41151
• FlyBaseID: FBgn0027950
• Length: 340
• Species: Drosophila melanogaster
• Sequence 2: NP_001075448.1
• Gene: Mecp2 / 17257
• MGIID: 99918
• Length: 501
• Species: Mus musculus
• Alignment Length: 427
• Identity: 80/427 - (18%)
• Similarity: 122/427 - (28%)
• Gaps: 165/427 - (38%)

  Fly    15 DCSVLPKGWQRD-EVRKSGSSANNNASSNNNSSATASSNNNNNKVDVFYYSSPTGKRAEGKPQDI 78
            |...||:||.|. :.||||.||                    .|.|| |..:|.||....|.:.|
Mouse   113 DDPTLPEGWTRKLKQRKSGRSA--------------------GKYDV-YLINPQGKAFRSKVELI 156

  Fly    79 AI-----------PDF---------------QPGKMPHC----------------------ALPS 95
            |.           .||               :|.|.|..                      |..|
Mouse   157 AYFEKVGDTSLDPNDFDFTVTGRGSPSRREQKPPKKPKSPKAPGTGRGRGRPKGSGTGRPKAAAS 221

  Fly    96 PSISLYR---------CSAMPLPIASGG---GNGATSGSAANALKR----------------KFA 132
            ..:.:.|         ...||...:.||   |.|||:.:....:||                |..
Mouse   222 EGVQVKRVLEKSPGKLVVKMPFQASPGGKGEGGGATTSAQVMVIKRPGRKRKAEADPQAIPKKRG 286

  Fly   133 RSQGGNAAGAAGAAPPAATASSAATATAASASPSTANRQQQQIEL------------------SR 179
            |..|...|.||..|...|...|:..:...:..|....:.::.:.:                  .:
Mouse   287 RKPGSVVAAAAAEAKKKAVKESSIRSVHETVLPIKKRKTRETVSIEVKEVVKPLLVSTLGEKSGK 351

  Fly   180 ALRTDVSLVP--------PIRQTASIFKQPVTVIRNHKQD-----------PAKAKNEPKHGTRE 225
            .|:|..|  |        |..:::|....|.....:|...           |:....||:  :.|
Mouse   352 GLKTCKS--PGRKSKESSPKGRSSSASSPPKKEHHHHHHHSESTKAPMPLLPSPPPPEPE--SSE 412

  Fly   226 KP----------KQLFWEKRLERLRACHDSGEELDDISLPKTIRTVGPNVNEQTVLQSVATALHM 280
            .|          ..:..|:::.|       |..|:....||......|         .|||...:
Mouse   413 DPISPPEPQDLSSSICKEEKMPR-------GGSLESDGCPKEPAKTQP---------MVATTTTV 461

  Fly   281 LNAGVHGQSSTKADLTKNAMAFMNPEQPLMHAVIISE 317
            .....|.....:.|:..::|...|.|:|:.....::|
Mouse   462 AEKYKHRGEGERKDIVSSSMPRPNREEPVDSRTPVTE 498

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
MBD-like	NP_001262421.1	MBD	13..98	CDD:279737	29/131 (22%)
		MBDa	172..241	CDD:293172	15/115 (13%)
		MBD_C	246..338	CDD:290755	15/72 (21%)
Mecp2	NP_001075448.1	MBD	109..186	CDD:128673	24/93 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4161
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1431783at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.820