Protein Alignment MBD-like and mbd2

DIOPT Version :10

• Sequence 1: NP_001262421.1
• Gene: MBD-like / 41151
• FlyBaseID: FBgn0027950
• Length: 340
• Species: Drosophila melanogaster
• Sequence 2: XP_012813111.2
• Gene: mbd2 / 100216281
• XenbaseID: XB-GENE-493776
• Length: 265
• Species: Xenopus tropicalis
• Alignment Length: 340
• Identity: 113/340 - (33%)
• Similarity: 164/340 - (48%)
• Gaps: 107/340 - (31%)

  Fly     9 IERKRVDCSVLPKGWQRDEV-RKSGSSANNNASSNNNSSATASSNNNNNKVDVFYYSSPTGKRAE 72
            :|::|::|..||.||:::|| ||||.||                    .|.||:|| ||.||:..
 Frog     1 MEKRRMECPALPPGWKKEEVIRKSGLSA--------------------GKSDVYYY-SPNGKKFR 44

  Fly    73 GKPQ---------DIAIPDFQPGKMPHCALPSPSISLYRCSAMPLPIASGGGNGATSGSAANALK 128
            .|||         |::..||:.|||                 ||                 :.|:
 Frog    45 SKPQLARYLGNSVDLSSFDFRTGKM-----------------MP-----------------SKLQ 75

  Fly   129 RKFARSQGGNAAGAAGAAPPAATASSAATATAASASPSTANRQQQQIELSRALRTDVSLVPPIRQ 193
            :...|.:.                           .|...|:.          :.|::...||||
 Frog    76 KNKQRLRN---------------------------DPLNQNKS----------KPDLNTTLPIRQ 103

  Fly   194 TASIFKQPVTVIRNHKQDPAKAKNEPKHGTREKPKQLFWEKRLERLRACHDSGEELDDISLPKTI 258
            ||||||||||.:.||..:  |.|::|:. ..|:|:|||||||||.|.|...:.:.:..:.|||.:
 Frog   104 TASIFKQPVTKVTNHPSN--KVKSDPQR-VIEQPRQLFWEKRLEGLSASDVTEQVIKPMELPKGL 165

  Fly   259 RTVGPNVNEQTVLQSVATALHMLNAGVHGQSSTKADLTKNAMAFMNPEQPLMHAVIISEDDIRKQ 323
            :.|||..||||:|.::|:|||..:|.:.||.|  |.:.||...::|..|||..|.::::||||||
 Frog   166 QGVGPGNNEQTLLAAIASALHTSSAPITGQLS--AAVEKNPSVWLNTSQPLCKAFLVTDDDIRKQ 228

  Fly   324 EDRVGVARRKLQDAL 338
            |:||...|:||::||
 Frog   229 EERVQNVRKKLEEAL 243

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
MBD-like	NP_001262421.1	MBD	9..101	CDD:396147	33/101 (33%)
		MBDa	171..241	CDD:465179	32/69 (46%)
		MBD_C	245..338	CDD:464072	39/92 (42%)
mbd2	XP_012813111.2	MeCP2_MBD	7..70	CDD:238690	31/100 (31%)
		MBDa	82..148	CDD:465179	34/105 (32%)
		MBD_C	152..243	CDD:464072	39/92 (42%)