Protein Alignment AP-1mu and APM2

DIOPT Version :10

• Sequence 1: NP_649906.1
• Gene: AP-1mu / 41150
• FlyBaseID: FBgn0024833
• Length: 426
• Species: Drosophila melanogaster
• Sequence 2: NP_011844.1
• Gene: APM2 / 856367
• SGDID: S000001011
• Length: 605
• Species: Saccharomyces cerevisiae
• Alignment Length: 609
• Identity: 147/609 - (24%)
• Similarity: 235/609 - (38%)
• Gaps: 210/609 - (34%)

  Fly     3 SSAIFVLDVKGKVLISRNYRG-DNIDMAVIDKFMPLLMEREEEGLITPILQTAETTFAYIKTNNL 66
            ||::|:||...:.|:|:|.|. .|:. :|:..|.....:..     .|||...:..|.::|.:.|
Yeast     2 SSSLFILDENLEPLVSKNIRALPNLS-SVLSSFKQCYHDGS-----PPILSQNDWFFIHLKRDFL 60

  Fly    67 YIVST--TPRNKNVNIALVFVFLHKIAQVFVEYF--KELEEESIRDNFVIIYELLDELLDFGYPQ 127
            :.||.  |....|:::..:..||.:...:..:||  :.|.:..|.||.:::.||:||.:|||..|
Yeast    61 HFVSVIHTTDKPNIDLMTILAFLEQFYHLLQKYFEIEVLTKNVILDNILLVLELIDECIDFGIVQ 125

  Fly   128 TTDSKILQEYI------------------------------------------------------ 138
            .||..|:::||
Yeast   126 VTDPSIIKDYIRVKVNVPRVTVDNEEWSPGEESSSSSGSDSDSEYSNTNKRKDKKKKRKKKKGTK 190

  Fly   139 -----------------------------------------------TQEGHKLELQPRIPVAVT 156
                                                           ..:|:.|.:...|...:.
Yeast   191 GKSVGKSKLKSIMVNNKENRGINVVETVKETLRNKNDTGKEAANDELPNDGNDLYINGDIAKTII 255

  Fly   157 NAVSWRSEGIKYRKNEVFLDVIESVNLLANANGNVLRSEIV-GAIKMRVYLSGMPELRLGLNDKV 220
            ..:|||::||.|.|||.||||||.|..|.:....|:|..:: |.|..|.||||||:|::.:| |:
Yeast   256 MPISWRTKGIHYAKNEFFLDVIERVQYLMDFEKGVIRKNLIHGEIVCRCYLSGMPKLKISIN-KI 319

  Fly   221 LFESTGRGKSKSVE-LEDVKFHQCVRL---SRFEND-----------------RTISFIPPDGEF 264
            |        ::..: :.:..|||||.|   :..|.|                 |.|.||||||||
Yeast   320 L--------NRDPQFMSNSSFHQCVSLDSINTIEKDEEKNSDDDAGLQAATDAREIEFIPPDGEF 376

  Fly   265 ELMSYRLNTHVK--PLIWIE--SVIERHAHSRVEYMIKAKSQFKRRSTANNVEIVIPVPADADSP 325
            .|..|.|..|||  |::.::  .:..:....:::.:.|.::.||..::.:.:.:.||:.......
Yeast   377 VLCQYELKRHVKDAPMVRLKDFEIKPKLKKFKIQIVTKIQTNFKPTNSTSKLNVRIPLTKVFQEY 441

  Fly   326 K--------FKTTIGSCKYAPEQNAIIWTIKSFPGGKEY-------------------LMRAHFG 363
            |        ||..||...:....:.::|.|::..|.:|:                   .|.|.|.
Yeast   442 KIDLSKQIRFKANIGKVVFNLSDDFLLWEIQTMKGHREHSTNKSSQYNSDEDDPNTCASMVAEFP 506

  Fly   364 LPSVESED------NTEGKPP-----------------------------IQVRFEIPYFTTSGI 393
            |.:.|..|      .|...||                             :.:.|||||.|.||:
Yeast   507 LFNQEEYDRLQEEMKTSMNPPPLRTGPRLEELYRQVHDQQTSHVTPRDKLVNIDFEIPYCTCSGL 571

  Fly   394 QVRYLKIIE-KSGYQALPWVRYIT 416
            :|.|||:.| :..||:.|||||.|
Yeast   572 KVEYLKVEEPQLQYQSFPWVRYKT 595

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
AP-1mu	NP_649906.1	AP1_Mu_N	4..145	CDD:341439	43/246 (17%)
		AP-1_Mu1A_Cterm	155..425	CDD:271166	101/351 (29%)
APM2	NP_011844.1	AP_Mu_N	3..138	CDD:341432	42/140 (30%)
		AP-1_Mu1_Cterm	256..603	CDD:271158	101/349 (29%)