DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment AP-1mu and HAP13

DIOPT Version :9

Sequence 1:	NP_649906.1	Gene:	AP-1mu / 41150	FlyBaseID:	FBgn0024833	Length:	426	Species:	Drosophila melanogaster
Sequence 2:	NP_176277.1	Gene:	HAP13 / 842372	AraportID:	AT1G60780	Length:	428	Species:	Arabidopsis thaliana

Alignment Length:	426	Identity:	256/426 - (60%)
Similarity:	345/426 - (80%)	Gaps:	6/426 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 SSSAIFVLDVKGKVLISRNYRGDNIDMAVIDKFMPLLMEREEEGLIT-PILQTAETTFAYIKTNN 65
            ::||:|:||:||:||:.|:|||| :..|..::|...|:|:|.:.... |:......|:.:::.:|
plant     4 AASALFLLDIKGRVLVWRDYRGD-VSAAQAERFFTKLIEKEGDSQSNDPVAYDNGVTYMFVQHSN 67

  Fly    66 LYIVSTTPRNKNVNIALVFVFLHKIAQVFVEYFKELEEESIRDNFVIIYELLDELLDFGYPQTTD 130
            :|::..:  .:|.|.|.:..|||::..||..||:||||||:|||||::||||||::||||||.|:
plant    68 VYLMIAS--RQNCNAASLLFFLHRVVDVFKHYFEELEEESLRDNFVVVYELLDEMMDFGYPQYTE 130

  Fly   131 SKILQEYITQEGHKLELQPRIPVAVTNAVSWRSEGIKYRKNEVFLDVIESVNLLANANGNVLRSE 195
            ::||.|:|..:.:::|:..|.|:|||||||||||||:|:||||||||||:||:|.|:||.::||:
plant   131 ARILSEFIKTDAYRMEVTQRPPMAVTNAVSWRSEGIQYKKNEVFLDVIENVNILVNSNGQIVRSD 195

  Fly   196 IVGAIKMRVYLSGMPELRLGLNDKVLFESTGRG-KSKSVELEDVKFHQCVRLSRFENDRTISFIP 259
            :|||:|||.||:||||.:|||||:||.|:.||. |.|:::|||:||||||||:||||||||||||
plant   196 VVGALKMRTYLTGMPECKLGLNDRVLLEAQGRATKGKAIDLEDIKFHQCVRLARFENDRTISFIP 260

  Fly   260 PDGEFELMSYRLNTHVKPLIWIESVIERHAHSRVEYMIKAKSQFKRRSTANNVEIVIPVPADADS 324
            |||.|:||:|||:|.||||||:|:.||.|:.||||.:|||:||||.||||.||||.:|||.||.:
plant   261 PDGAFDLMTYRLSTQVKPLIWVEAQIESHSRSRVEMLIKARSQFKERSTATNVEIELPVPTDASN 325

  Fly   325 PKFKTTIGSCKYAPEQNAIIWTIKSFPGGKEYLMRAHFGLPSVESEDNT-EGKPPIQVRFEIPYF 388
            |..:|::||..||||::|::|.||||||.|||::||.|.|||:.:|:.| |.|.||:|:||||||
plant   326 PTVRTSLGSASYAPEKDALVWKIKSFPGNKEYMLRAEFHLPSITAEEATPERKAPIRVKFEIPYF 390

  Fly   389 TTSGIQVRYLKIIEKSGYQALPWVRYITQNGDYQLR 424
            |.||||||||||||||||||||||||||..|:|:||
plant   391 TVSGIQVRYLKIIEKSGYQALPWVRYITMAGEYELR 426

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
AP-1mu	NP_649906.1	AP1_Mu_N	4..145	CDD:341439	61/141 (43%)
AP-1mu	NP_649906.1	AP-1_Mu1A_Cterm	155..425	CDD:271166	191/272 (70%)
HAP13	NP_176277.1	AP1_Mu_N	6..145	CDD:341439	61/141 (43%)
HAP13	NP_176277.1	AP-1_Mu1_Cterm	156..426	CDD:271158	188/269 (70%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	396	1.000	Domainoid score	I140
eggNOG	1	0.900	-	-		E1_KOG0937
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H4017
Inparanoid	1	1.050	537	1.000	Inparanoid score	I267
OMA	1	1.010	-	-		QHG54006
OrthoDB	1	1.010	-	-		D725236at2759
OrthoFinder	1	1.000	-	-		FOG0001611
OrthoInspector	1	1.000	-	-		otm3513
orthoMCL	1	0.900	-	-		OOG6_101263
Panther	1	1.100	-	-	LDO	PTHR10529
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X1021
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	14	13.840