Protein Alignment AP-1mu and AP5M1

DIOPT Version :9

• Sequence 1: NP_649906.1
• Gene: AP-1mu / 41150
• FlyBaseID: FBgn0024833
• Length: 426
• Species: Drosophila melanogaster
• Sequence 2: XP_011535242.1
• Gene: AP5M1 / 55745
• HGNCID: 20192
• Length: 504
• Species: Homo sapiens
• Alignment Length: 407
• Identity: 88/407 - (21%)
• Similarity: 149/407 - (36%)
• Gaps: 100/407 - (24%)

  Fly    37 LLMEREEEGLITPILQTAETTFAYIKTNNLY----IVSTT--PRNKNVNIALV---FVFLHKIAQ 92
            ||:..||   :.|::       |::|.:.:|    :|..|  ||...::::.|   |.||..| |
Human   100 LLIGGEE---LWPVV-------AFLKNDMIYACVPLVEQTLSPRPPLISVSGVSQGFEFLFGI-Q 153

  Fly    93 VFVEYFKELEEESIRDNFVIIYELLDELLDFGYPQTTDSKILQEYITQEGHKLELQPRIPVAVTN 157
            .|: |..:..:..:......:.:||.:...||   |.....||..:.........||:      .
Human   154 DFL-YSGQKNDSELNTKLSQLPDLLLQACPFG---TLLDANLQNSLDNTNFASVTQPQ------K 208

  Fly   158 AVSWRSEGIKYRKNEVFLDVIESV-NLLANANGNVLRSEIVGAIKMRVYLSG-MPELRLGLNDKV 220
            ..:|:: |....|.:|.:.:.|.| ::..:..|.....::||.:..:..|.| ||.:.:.|:
Human   209 QPAWKT-GTYKGKPQVSISITEKVKSMQYDKQGIADTWQVVGTVTCKCDLEGIMPNVTISLS--- 269

  Fly   221 LFESTGRGKSKSVELEDVKFHQCVRL----------------SRFENDRTISFIPPDGEFELMSY 269
             ..:.|.      .|:|:..|.||..                |.|.......|.||...|.|..|
Human   270 -LPTNGS------PLQDILVHPCVTSLDSAILTSSSIDAMDDSAFSGPYKFPFTPPLESFNLCFY 327

  Fly   270 RLNTHVKPLIWIESVIERHAHSRVEYMIKAKSQFKRRSTANNVEIVIPVPADADSP--------- 325
            .....|.|::....:.|.....|:...:|.     ..|..||.|.     .:|..|
Human   328 TSQVPVPPILGFYQMKEEEVQLRITINLKL-----HESVKNNFEF-----CEAHIPFYNRGPITH 382

  Fly   326 -KFKTTIGSCKYAPEQNAIIWTI-KSFPGGKEYLM--RAHFGLPSVESEDNTEGKPP-------- 378
             ::||:.|..:...|::.:||.| :.||...|..:  ...||..|.|       |.|
Human   383 LEYKTSFGQLEVFREKSLLIWIIGQKFPKSMEISLSGTVTFGAKSHE-------KQPFDPICTGE 440

  Fly   379 ---IQVRFEIPYFTTSG 392
               :::.|.|..:|.:|
Human   441 TAYLKLHFRILDYTLTG 457

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
AP-1mu	NP_649906.1	AP1_Mu_N	4..145	CDD:341439	27/116 (23%)
		AP-1_Mu1A_Cterm	155..425	CDD:271166	59/280 (21%)
AP5M1	XP_011535242.1	AP_MuD_MHD	210..496	CDD:271164	59/276 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0937
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810