DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment AP-1mu and ap1m2

DIOPT Version :9

Sequence 1:	NP_649906.1	Gene:	AP-1mu / 41150	FlyBaseID:	FBgn0024833	Length:	426	Species:	Drosophila melanogaster
Sequence 2:	NP_991277.1	Gene:	ap1m2 / 403021	ZFINID:	ZDB-GENE-041114-20	Length:	424	Species:	Danio rerio

Alignment Length:	427	Identity:	311/427 - (72%)
Similarity:	374/427 - (87%)	Gaps:	5/427 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MSSSAIFVLDVKGKVLISRNYRGDNIDMAVIDKFMPLLMEREEEGLITPILQTAETTFAYIKTNN 65
            ||:||:||||:||||||.|||:|| :||:.||.|..|||::||:|||:|::......|.:||.||
Zfish     1 MSASAVFVLDLKGKVLICRNYKGD-VDMSEIDHFFTLLMQQEEDGLISPVMSHGNVHFLWIKHNN 64

  Fly    66 LYIVSTTPRNKNVNIALVFVFLHKIAQVFVEYFKELEEESIRDNFVIIYELLDELLDFGYPQTTD 130
            ||:|:||  |||.|.:||:.||:|:.:||.|||||||||||:||||::|||||||:|||:|||||
Zfish    65 LYLVATT--NKNSNASLVYAFLYKLVEVFTEYFKELEEESIQDNFVVVYELLDELMDFGFPQTTD 127

  Fly   131 SKILQEYITQEGHKLEL-QPRIPVAVTNAVSWRSEGIKYRKNEVFLDVIESVNLLANANGNVLRS 194
            ||||||||||:|.|||: :.::|..||||||||||||:|:|||||:|||||:|:|.||||:|:.|
Zfish   128 SKILQEYITQQGQKLEVAKTKVPTTVTNAVSWRSEGIRYKKNEVFIDVIESINVLVNANGSVMSS 192

  Fly   195 EIVGAIKMRVYLSGMPELRLGLNDKVLFESTGRGKSKSVELEDVKFHQCVRLSRFENDRTISFIP 259
            :|||.|:::..|||||||||||||:|||..|||.|.|:|.:|||||||||||||||:||||||||
Zfish   193 DIVGCIRLKTMLSGMPELRLGLNDRVLFALTGRDKGKTVVMEDVKFHQCVRLSRFESDRTISFIP 257

  Fly   260 PDGEFELMSYRLNTHVKPLIWIESVIERHAHSRVEYMIKAKSQFKRRSTANNVEIVIPVPADADS 324
            ||||.||||||:|||||||||||||||:.:|||||.|:|||.|||::|.||||||.:|||:||||
Zfish   258 PDGESELMSYRINTHVKPLIWIESVIEKFSHSRVEIMVKAKGQFKKQSVANNVEIRVPVPSDADS 322

  Fly   325 PKFKTTIGSCKYAPEQNAIIWTIKSFPGGKEYLMRAHFGLPSVESEDNTEGKPPIQVRFEIPYFT 389
            |||||:.|..||.||:|.::|:|||||||||:||||||||||||: |..||||||.|:||||||.
Zfish   323 PKFKTSTGHAKYVPEKNLVVWSIKSFPGGKEFLMRAHFGLPSVEN-DELEGKPPITVKFEIPYFP 386

  Fly   390 TSGIQVRYLKIIEKSGYQALPWVRYITQNGDYQLRTN 426
            .|||||||:|||||||||||||||||||:||||||||
Zfish   387 VSGIQVRYMKIIEKSGYQALPWVRYITQSGDYQLRTN 423

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
AP-1mu	NP_649906.1	AP1_Mu_N	4..145	CDD:341439	93/140 (66%)
AP-1mu	NP_649906.1	AP-1_Mu1A_Cterm	155..425	CDD:271166	209/269 (78%)
ap1m2	NP_991277.1	AP-1_Mu1B_Cterm	154..421	CDD:271167	207/267 (78%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	180	1.000	Domainoid score	I3451
eggNOG	1	0.900	-	-		E1_KOG0937
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54006
OrthoDB	1	1.010	-	-		D246783at33208
OrthoFinder	1	1.000	-	-		FOG0001611
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_101263
Panther	1	1.100	-	-	O	PTHR10529
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X1021
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	11	10.790