DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment AP-1mu and ap2m1a

DIOPT Version :9

Sequence 1:NP_649906.1 Gene:AP-1mu / 41150 FlyBaseID:FBgn0024833 Length:426 Species:Drosophila melanogaster
Sequence 2:NP_001278284.1 Gene:ap2m1a / 321051 ZFINID:ZDB-GENE-030131-9784 Length:441 Species:Danio rerio


Alignment Length:443 Identity:179/443 - (40%)
Similarity:272/443 - (61%) Gaps:31/443 - (6%)


- Green bases have known domain annotations that are detailed below.


  Fly     6 IFVLDVKGKVLISRNYRGDNIDMAVIDKFMPLLMEREEEGLITPILQTAETTFAYIKTNNLYIVS 70
            :|:.:.||:|||||.|| |:|....:|.|...::...:: :.:|:...|.|:|.::|.:|:::.:
Zfish     5 LFIYNHKGEVLISRVYR-DDIGRNAVDAFRVNVIHARQQ-VRSPVTNIARTSFFHVKRSNIWLAA 67

  Fly    71 TTPRNKNVNIALVFVFLHKIAQVFVEYFKELEEESIRDNFVIIYELLDELLDFGYPQTTDSKILQ 135
            .|  .:|||.|:||.||:|:..|...||.::.||:|::|||:|||||||:|||||||.:::..|:
Zfish    68 VT--KQNVNAAMVFEFLYKMCDVMTAYFGKISEENIKNNFVLIYELLDEILDFGYPQNSETGALK 130

  Fly   136 EYITQEGHK-----LELQPRIPVAVTNAVSWRSEGIKYRKNEVFLDVIESVNLLANANGNVLRSE 195
            .:|||:|.|     .|.|.:|...||..:.||.||||||:||:||||:||||||.:..|.||.:.
Zfish   131 TFITQQGIKGQHQTKEEQSQITSQVTGQIGWRREGIKYRRNELFLDVLESVNLLMSPQGQVLSAH 195

  Fly   196 IVGAIKMRVYLSGMPELRLGLNDKVLFESTGR-------GKS-------KSVELEDVKFHQCVRL 246
            :.|.:.|:.|||||||.:.|:|||::.:..|:       |||       :|:.::|..|||||||
Zfish   196 VSGRVVMKSYLSGMPECKFGMNDKIVIDKQGKGGTTDDAGKSELGGSGKQSIAIDDCTFHQCVRL 260

  Fly   247 SRFENDRTISFIPPDGEFELMSYRLNTHVKPLIWIESVIERHAHSRVEYMIKAKSQFKRRSTANN 311
            |:|:::|:|||||||||:|||.||....:.....:..::.....:::|..:..||.||....|..
Zfish   261 SKFDSERSISFIPPDGEYELMRYRTTKDIILPFRVIPLVREVGRTKLEVKVVIKSNFKPSLLAQK 325

  Fly   312 VEIVIPVPADADSPKFKTTIGSCKYAPEQNAIIWTIKSFPGGKEYLMRAHFGLPSVESEDNTE-G 375
            :|:.||.|.:....:.....|..||...:|||:|.||...|.||..:.|...|  :.:.|..: .
Zfish   326 IEVRIPTPLNTSGVQVICMKGKAKYKASENAIVWKIKRMAGMKESQISAEIEL--LPTNDKKKWA 388

  Fly   376 KPPIQVRFEIPYFTTSGIQVRYLKIIEK----SGYQALPWVRYITQNGDYQLR 424
            :|||.:.||:| |..||::|||||:.|.    |.:..:.|||||.::|.|:.|
Zfish   389 RPPISMNFEVP-FAPSGLKVRYLKVFESKLNYSDHDVIKWVRYIGRSGIYETR 440

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
AP-1muNP_649906.1 AP1_Mu_N 4..145 CDD:341439 59/143 (41%)
AP-1_Mu1A_Cterm 155..425 CDD:271166 117/289 (40%)
ap2m1aNP_001278284.1 AP-2_Mu2_Cterm 168..440 CDD:271159 108/274 (39%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D725236at2759
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
21.920

Return to query results.
Submit another query.