DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment AP-1mu and Ap1m1

DIOPT Version :9

Sequence 1:	NP_649906.1	Gene:	AP-1mu / 41150	FlyBaseID:	FBgn0024833	Length:	426	Species:	Drosophila melanogaster
Sequence 2:	NP_001037704.1	Gene:	Ap1m1 / 306332	RGDID:	1307653	Length:	423	Species:	Rattus norvegicus

Alignment Length:	426	Identity:	351/426 - (82%)
Similarity:	390/426 - (91%)	Gaps:	5/426 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MSSSAIFVLDVKGKVLISRNYRGDNIDMAVIDKFMPLLMEREEEGLITPILQTAETTFAYIKTNN 65
            ||:||::|||:||||||.|||||| :||:.::.|||:|||:||||:::|||......|.:||.||
  Rat     1 MSASAVYVLDLKGKVLICRNYRGD-VDMSEVEHFMPILMEKEEEGMLSPILAHGGVRFMWIKHNN 64

  Fly    66 LYIVSTTPRNKNVNIALVFVFLHKIAQVFVEYFKELEEESIRDNFVIIYELLDELLDFGYPQTTD 130
            ||:|:|:  .||..::|||.||:|:.|||.|||||||||||||||||||||||||:|||||||||
  Rat    65 LYLVATS--KKNACVSLVFSFLYKVVQVFSEYFKELEEESIRDNFVIIYELLDELMDFGYPQTTD 127

  Fly   131 SKILQEYITQEGHKLEL-QPRIPVAVTNAVSWRSEGIKYRKNEVFLDVIESVNLLANANGNVLRS 194
            ||||||||||||||||. .||.|..|||||||||||||||||||||||||:||||.:||||||||
  Rat   128 SKILQEYITQEGHKLETGAPRPPATVTNAVSWRSEGIKYRKNEVFLDVIEAVNLLVSANGNVLRS 192

  Fly   195 EIVGAIKMRVYLSGMPELRLGLNDKVLFESTGRGKSKSVELEDVKFHQCVRLSRFENDRTISFIP 259
            ||||:|||||:|||||||||||||||||::|||||||||||||||||||||||||||||||||||
  Rat   193 EIVGSIKMRVFLSGMPELRLGLNDKVLFDNTGRGKSKSVELEDVKFHQCVRLSRFENDRTISFIP 257

  Fly   260 PDGEFELMSYRLNTHVKPLIWIESVIERHAHSRVEYMIKAKSQFKRRSTANNVEIVIPVPADADS 324
            |||||||||||||||||||||||||||:|:|||:|||:|||||||||||||||||.||||.||||
  Rat   258 PDGEFELMSYRLNTHVKPLIWIESVIEKHSHSRIEYMVKAKSQFKRRSTANNVEIHIPVPNDADS 322

  Fly   325 PKFKTTIGSCKYAPEQNAIIWTIKSFPGGKEYLMRAHFGLPSVESEDNTEGKPPIQVRFEIPYFT 389
            ||||||:||.|:.||.:.|:|:||||||||||||||||||||||:||. ||||||.|:|||||||
  Rat   323 PKFKTTVGSVKWVPENSEIVWSIKSFPGGKEYLMRAHFGLPSVEAEDK-EGKPPISVKFEIPYFT 386

  Fly   390 TSGIQVRYLKIIEKSGYQALPWVRYITQNGDYQLRT 425
            ||||||||||||||||||||||||||||||||||||
  Rat   387 TSGIQVRYLKIIEKSGYQALPWVRYITQNGDYQLRT 422

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
AP-1mu	NP_649906.1	AP1_Mu_N	4..145	CDD:341439	99/140 (71%)
AP-1mu	NP_649906.1	AP-1_Mu1A_Cterm	155..425	CDD:271166	242/269 (90%)
Ap1m1	NP_001037704.1	AP1_Mu_N	4..142	CDD:341439	99/140 (71%)
Ap1m1	NP_001037704.1	AP-1_Mu1A_Cterm	153..422	CDD:271166	242/269 (90%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166348836
Domainoid	1	1.000	490	1.000	Domainoid score	I363
eggNOG	1	0.900	-	-		E1_KOG0937
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H4017
Inparanoid	1	1.050	705	1.000	Inparanoid score	I634
OMA	1	1.010	-	-		QHG54006
OrthoDB	1	1.010	-	-		D246783at33208
OrthoFinder	1	1.000	-	-		FOG0001611
OrthoInspector	1	1.000	-	-		oto95777
orthoMCL	1	0.900	-	-		OOG6_101263
Panther	1	1.100	-	-	LDO	PTHR10529
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X1021
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	16	15.770