DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment AP-1mu and apm1

DIOPT Version :9

Sequence 1:	NP_649906.1	Gene:	AP-1mu / 41150	FlyBaseID:	FBgn0024833	Length:	426	Species:	Drosophila melanogaster
Sequence 2:	NP_595781.1	Gene:	apm1 / 2541306	PomBaseID:	SPBP16F5.07	Length:	426	Species:	Schizosaccharomyces pombe

Alignment Length:	427	Identity:	266/427 - (62%)
Similarity:	346/427 - (81%)	Gaps:	8/427 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 SSAIFVLDVKGKVLISRNYRGDNIDMAVIDKFMPLLME-REEEGLITPILQTAETTFAYIKTNNL 66
            :||||||::||||:|||:||.| |.|:|::||:||..| .||:|..||.|......:.||..|::
pombe     2 ASAIFVLNLKGKVIISRDYRAD-IPMSVVEKFLPLKSEVEEEQGFSTPCLTHEGINYIYIHHNDV 65

  Fly    67 YIVSTTPRNKNVNIALVFVFLHKIAQVFVEYFKELEEESIRDNFVIIYELLDELLDFGYPQTTDS 131
            |:::.:..|.:....|  |||.|:|.||::|||||:|||||||||::||||||::|||:||||::
pombe    66 YLLALSKMNSDAMEML--VFLRKMADVFIDYFKELQEESIRDNFVLVYELLDEIMDFGFPQTTET 128

  Fly   132 KILQEYITQEGHKLELQPRIPVAVTNAVSWRSEGIKYRKNEVFLDVIESVNLLANANGNVLRSEI 196
            |||||||||..:.::.....|:|:|||:|||||||.||||||||||||||||:|.|:|.|::|||
pombe   129 KILQEYITQTSNTVKKHAPPPIAMTNAISWRSEGIHYRKNEVFLDVIESVNLIAAADGTVIQSEI 193

  Fly   197 VGAIKMRVYLSGMPELRLGLNDKVLFESTGRG-KSKSVELEDVKFHQCVRLSRFENDRTISFIPP 260
            :|.::::.|||||||||||||||||||:.||. |..:||:|||||||||||:|||||||||||||
pombe   194 LGKVRLKCYLSGMPELRLGLNDKVLFEAAGRTIKGNTVEMEDVKFHQCVRLARFENDRTISFIPP 258

  Fly   261 DGEFELMSYRLNTHVKPLIWIESVIERHAHSRVEYMIKAKSQFKRRSTANNVEIVIPVPADADSP 325
            ||||:|||||::::|:||||:|.....|:.||:|:|:|||:|||:|..||||:|:||||.|||||
pombe   259 DGEFDLMSYRMSSNVRPLIWVECESIVHSGSRIEFMVKAKAQFKKRCIANNVQIIIPVPEDADSP 323

  Fly   326 KFKTTIGSCKYAPEQNAIIWTIKSFPGGKEYLMRAHFGLPSVESED-NTEGKPPIQVRFEIPYFT 389
            :|:|:.|..:|||||.|::|.||.|.||||:.|||..|||||::|| ..:.|.|:|::|.|||||
pombe   324 RFQTSNGHVQYAPEQAAMVWNIKKFAGGKEFFMRAEMGLPSVKNEDIQVQKKRPVQLKFAIPYFT 388

  Fly   390 TSGIQVRYLKIIE-KSGYQALPWVRYITQNG-DYQLR 424
            |||||||||||.| |..|.|:|||||:|||| :|.:|
pombe   389 TSGIQVRYLKITEPKLNYHAMPWVRYVTQNGTEYSIR 425

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
AP-1mu	NP_649906.1	AP1_Mu_N	4..145	CDD:341439	79/141 (56%)
AP-1mu	NP_649906.1	AP-1_Mu1A_Cterm	155..425	CDD:271166	185/274 (68%)
apm1	NP_595781.1	AP-1_Mu1_Cterm	153..423	CDD:271158	183/269 (68%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	374	1.000	Domainoid score	I135
eggNOG	1	0.900	-	-		E1_KOG0937
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H4017
Inparanoid	1	1.050	535	1.000	Inparanoid score	I210
OMA	1	1.010	-	-		QHG54006
OrthoFinder	1	1.000	-	-		FOG0001611
OrthoInspector	1	1.000	-	-		oto100587
orthoMCL	1	0.900	-	-		OOG6_101263
Panther	1	1.100	-	-	LDO	PTHR10529
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R59
SonicParanoid	1	1.000	-	-		X1021
TreeFam	1	0.960	-	-
	14	13.860