DRSC/TRiP Functional Genomics Resources

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Protein Alignment AP-1mu and Ap2m1

DIOPT Version :9

Sequence 1:NP_649906.1 Gene:AP-1mu / 41150 FlyBaseID:FBgn0024833 Length:426 Species:Drosophila melanogaster
Sequence 2:NP_033809.1 Gene:Ap2m1 / 11773 MGIID:1298405 Length:435 Species:Mus musculus


Alignment Length:437 Identity:179/437 - (40%)
Similarity:271/437 - (62%) Gaps:25/437 - (5%)


- Green bases have known domain annotations that are detailed below.


  Fly     6 IFVLDVKGKVLISRNYRGDNIDMAVIDKFMPLLMEREEEGLITPILQTAETTFAYIKTNNLYIVS 70
            :|:.:.||:|||||.|| |:|....:|.|...::...:: :.:|:...|.|:|.::|.:|:::.:
Mouse     5 LFIYNHKGEVLISRVYR-DDIGRNAVDAFRVNVIHARQQ-VRSPVTNIARTSFFHVKRSNIWLAA 67

  Fly    71 TTPRNKNVNIALVFVFLHKIAQVFVEYFKELEEESIRDNFVIIYELLDELLDFGYPQTTDSKILQ 135
            .|  .:|||.|:||.||:|:..|...||.::.||:|::|||:|||||||:|||||||.:::..|:
Mouse    68 VT--KQNVNAAMVFEFLYKMCDVMAAYFGKISEENIKNNFVLIYELLDEILDFGYPQNSETGALK 130

  Fly   136 EYITQEGHK-----LELQPRIPVAVTNAVSWRSEGIKYRKNEVFLDVIESVNLLANANGNVLRSE 195
            .:|||:|.|     .|.|.:|...||..:.||.||||||:||:||||:||||||.:..|.||.:.
Mouse   131 TFITQQGIKS
QHQTKEEQSQITSQVTGQIGWRREGIKYRRNELFLDVLESVNLLMSPQGQVLSAH 195

  Fly   196 IVGAIKMRVYLSGMPELRLGLNDKVLFESTGRGKS--------KSVELEDVKFHQCVRLSRFEND 252
            :.|.:.|:.|||||||.:.|:|||::.|..|:|.:        :|:.::|..||||||||:|:::
Mouse   196 VSGRVVMKSYLSGMPECKFGMNDKIVIEKQGKGTADETSKSGKQSIAIDDCTFHQCVRLSKFDSE 260

  Fly   253 RTISFIPPDGEFELMSYRLNTHVKPLIWIESVIERHAHSRVEYMIKAKSQFKRRSTANNVEIVIP 317
            |:|||||||||||||.||....:.....:..::.....:::|..:..||.||....|..:|:.||
Mouse   261 RSISFIPPDGEFELMRYRTTKDIILPFRVIPLVREVGRTKLEVKVVIKSNFKPSLLAQKIEVRIP 325

  Fly   318 VPADADSPKFKTTIGSCKYAPEQNAIIWTIKSFPGGKEYLMRAHFGLPSVESEDNTE-GKPPIQV 381
            .|.:....:.....|..||...:|||:|.||...|.||..:.|...|  :.:.|..: .:|||.:
Mouse   326 TPLNTSGVQVICMKGKAKYKASENAIVWKIKRMAGMKESQISAEIEL--LPTNDKKKWARPPISM 388

  Fly   382 RFEIPYFTTSGIQVRYLKIIEK----SGYQALPWVRYITQNGDYQLR 424
            .||:| |..||::|||||:.|.    |.:..:.|||||.::|.|:.|
Mouse   389 NFEVP-FAPSGLKVRYLKVFEPKLNYSDHDVIKWVRYIGRSGIYETR 434

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
AP-1muNP_649906.1 AP1_Mu_N 4..145 CDD:341439 59/143 (41%)
AP-1_Mu1A_Cterm 155..425 CDD:271166 117/283 (41%)
Ap2m1NP_033809.1 AP2_Mu_N 1..140 CDD:341440 58/138 (42%)
AP-2_Mu2_Cterm 168..434 CDD:271159 108/268 (40%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D725236at2759
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 1 1.000 - -
TreeFam 00.000 Not matched by this tool.
32.920

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