DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment AP-1mu and ap1m1

DIOPT Version :9

Sequence 1:	NP_649906.1	Gene:	AP-1mu / 41150	FlyBaseID:	FBgn0024833	Length:	426	Species:	Drosophila melanogaster
Sequence 2:	NP_001318056.1	Gene:	ap1m1 / 100330411	ZFINID:	ZDB-GENE-110126-1	Length:	423	Species:	Danio rerio

Alignment Length:	426	Identity:	354/426 - (83%)
Similarity:	388/426 - (91%)	Gaps:	5/426 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MSSSAIFVLDVKGKVLISRNYRGDNIDMAVIDKFMPLLMEREEEGLITPILQTAETTFAYIKTNN 65
            ||:||::|||:||||||.|||||| :||:.|:.||.|||::||||.::|||......|.:||.||
Zfish     1 MSASAVYVLDLKGKVLICRNYRGD-VDMSEIEHFMTLLMDKEEEGTLSPILAHGGVRFMWIKHNN 64

  Fly    66 LYIVSTTPRNKNVNIALVFVFLHKIAQVFVEYFKELEEESIRDNFVIIYELLDELLDFGYPQTTD 130
            ||:|:|:  .||..::|||.||:||.|||.|||||||||||||||||||||||||:|||||||||
Zfish    65 LYLVATS--KKNACVSLVFSFLYKIVQVFSEYFKELEEESIRDNFVIIYELLDELMDFGYPQTTD 127

  Fly   131 SKILQEYITQEGHKLEL-QPRIPVAVTNAVSWRSEGIKYRKNEVFLDVIESVNLLANANGNVLRS 194
            |||||||||||||||:. .||.|..||||||||||||||||||||||||||||||.:||||||||
Zfish   128 SKILQEYITQEGHKLDTGAPRPPATVTNAVSWRSEGIKYRKNEVFLDVIESVNLLVSANGNVLRS 192

  Fly   195 EIVGAIKMRVYLSGMPELRLGLNDKVLFESTGRGKSKSVELEDVKFHQCVRLSRFENDRTISFIP 259
            ||||:|||||:||||||||||||||||||:|||||||||||||||||||||||||||||||||||
Zfish   193 EIVGSIKMRVFLSGMPELRLGLNDKVLFENTGRGKSKSVELEDVKFHQCVRLSRFENDRTISFIP 257

  Fly   260 PDGEFELMSYRLNTHVKPLIWIESVIERHAHSRVEYMIKAKSQFKRRSTANNVEIVIPVPADADS 324
            |||||||||||||||||||||||||||:|:|||:|||||||||||||||||||||.||||.||||
Zfish   258 PDGEFELMSYRLNTHVKPLIWIESVIEKHSHSRIEYMIKAKSQFKRRSTANNVEIHIPVPTDADS 322

  Fly   325 PKFKTTIGSCKYAPEQNAIIWTIKSFPGGKEYLMRAHFGLPSVESEDNTEGKPPIQVRFEIPYFT 389
            ||||||:||.|:.||.:.|:|:||||||||||||||||||||||:||. ||||||.|:|||||||
Zfish   323 PKFKTTVGSVKWVPENSEIVWSIKSFPGGKEYLMRAHFGLPSVEAEDK-EGKPPISVKFEIPYFT 386

  Fly   390 TSGIQVRYLKIIEKSGYQALPWVRYITQNGDYQLRT 425
            ||||||||||||||||||||||||||||||||||||
Zfish   387 TSGIQVRYLKIIEKSGYQALPWVRYITQNGDYQLRT 422

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
AP-1mu	NP_649906.1	AP1_Mu_N	4..145	CDD:341439	100/140 (71%)
AP-1mu	NP_649906.1	AP-1_Mu1A_Cterm	155..425	CDD:271166	245/269 (91%)
ap1m1	NP_001318056.1	AP1_Mu_N	4..142	CDD:341439	100/140 (71%)
ap1m1	NP_001318056.1	AP-1_Mu1A_Cterm	153..422	CDD:271166	245/269 (91%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170589994
Domainoid	1	1.000	494	1.000	Domainoid score	I350
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	703	1.000	Inparanoid score	I644
OMA	1	1.010	-	-		QHG54006
OrthoDB	1	1.010	-	-		D246783at33208
OrthoFinder	1	1.000	-	-		FOG0001611
OrthoInspector	1	1.000	-	-		oto40462
orthoMCL	1	0.900	-	-		OOG6_101263
Panther	1	1.100	-	-	LDO	PTHR10529
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X1021
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	13	12.910