Protein Alignment BckdhA and Pdha

DIOPT Version :10

• Sequence 1: NP_649905.1
• Gene: BckdhA / 41149
• FlyBaseID: FBgn0037709
• Length: 439
• Species: Drosophila melanogaster
• Sequence 2: NP_726945.1
• Gene: Pdha / 31406
• FlyBaseID: FBgn0028325
• Length: 443
• Species: Drosophila melanogaster
• Alignment Length: 416
• Identity: 114/416 - (27%)
• Similarity: 167/416 - (40%)
• Gaps: 70/416 - (16%)

  Fly    40 SEDYANFPGAKAPFVSKLNLIQPEDYA---------PIPIYRVMDQDGYIADETQDPQLGREVVE 95
            |..:..|..|....|||.|     :||         |..::|:.:........|:|..|
  Fly    57 SSFFGLFQNAAQAGVSKTN-----NYATEATVQVNRPFKLHRLDEGPATEVKLTKDQAL------ 110

  Fly    96 KMFRDMVLLNTMDKI---LY-ESQRQGRISFYMTNFGEEASHIGSAAALEMRDLIYGQYREAGVL 156
            |.:..|..:..::..   || |...:|....|.   |:||..:|..||:...|.|...||..|..
  Fly   111 KYYTQMQTIRRLETAAGNLYKEKIIRGFCHLYS---GQEACAVGMKAAMRDVDNIISAYRVHGWT 172

  Fly   157 VWRGFRIDQFIDQCYGNTDDLGRGKQMPVH-YGSRELNFVTISSPLSTQMPQAVGAAYAMKLRPN 220
            ...|......:.:..|......|||...:| |..   ||...:..:..|:|...|...|.|.:.|
  Fly   173 YLMGVSPSGVLAELTGVQGGCARGKGGSMHMYAP---NFYGGNGIVGAQVPLGAGVGLACKYKGN 234

  Fly   221 NDACVVCYFGEGAASEGDAHAAFNFAATLGCPAILFCRNNGFAISTPSH------EQY-KGDGIA 278
            ...|:..| |:|||::|....|:|.|.....|.|..|.||.:.:.|.|.      :.| :||.:.
  Fly   235 GGMCLALY-GDGAANQGQVFEAYNMAYLWKLPVIFVCENNNYGMGTSSERASCNTDYYTRGDALP 298

  Fly   279 GRGPMGYGITTIRVDGTDVFAVYNAMKAAREYVLKENKPVVFEALAYRVGHHSTSDDSTAYRPAE 343
            |          |.|||.||.||.:|.:.|..|| ..:.|:|.|...||...||.||..|:||..|
  Fly   299 G----------IWVDGMDVLAVRSATEFAINYV-NTHGPLVMETNTYRYSGHSMSDPGTSYRTRE 352

  Fly   344 EIEIWNSVEHPISKLKRYMVHKGWFDETVENEYVKDIRKKVLKQI------AVSEKKLKPN--WR 400
            ||:.......||:..|...:..|    .:..:.||.|..||.|::      |.|:.:|..:  |.
  Fly   353 EIQEVRQKRDPITSFKELCIELG----LITTDEVKAIDLKVRKEVDEATAFAKSDAELGVSHLWT 413

  Fly   401 EMF--------EGVYAEMPDHLIEQR 418
            :::        .|..|...||:.|::
  Fly   414 DVYSNNLEPKLRGTIAYDIDHIQERK 439

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
BckdhA	NP_649905.1	TPP_E1_PDC_ADC_BCADC	97..389	CDD:238958	90/309 (29%)
Pdha	NP_726945.1	TPP_enzymes	78..426	CDD:470272	101/375 (27%)