DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment RnpS1 and SRSF2

DIOPT Version :9

Sequence 1:	NP_649903.1	Gene:	RnpS1 / 41147	FlyBaseID:	FBgn0037707	Length:	374	Species:	Drosophila melanogaster
Sequence 2:	NP_001182356.1	Gene:	SRSF2 / 6427	HGNCID:	10783	Length:	221	Species:	Homo sapiens

Alignment Length:	156	Identity:	58/156 - (37%)
Similarity:	71/156 - (45%)	Gaps:	28/156 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly   221 IHVGRLTRNVTKDHVFEIFSSFGDVKNVEFPVDRFHPNFGRGVAFVEYATPEDCESAMKHMDGGQ 285
            :.|..||...:.|.:..:|..:|.|.:|..|.||:... .||.|||.:....|.|.||..|||..
Human    16 LKVDNLTYRTSPDTLRRVFEKYGRVGDVYIPRDRYTKE-SRGFAFVRFHDKRDAEDAMDAMDGAV 79

  Fly   286 IDGQEITVSPVVLVKQRPP----MRRPSPPMRRPQNNRWRSPPQFNRFNNRGGGGGGGGGRRQSP 346
            :||:|:.|.  :....|||    .||..||.|.                    ||||.|.|.:||
Human    80 LDGRELRVQ--MARYGRPPDSHHSRRGPPPRRY--------------------GGGGYGRRSRSP 122

  Fly   347 MRNRRSPRRRSRSPIRRRRRSNSSDS 372
            .|.||| |.||||..|.|.||..|.|
Human   123 RRRRRS-RSRSRSRSRSRSRSRYSRS 147

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
RnpS1	NP_649903.1	RRM	<196..>301	CDD:223796	27/79 (34%)
RnpS1	NP_649903.1	RRM_RNPS1	221..294	CDD:240811	26/72 (36%)
SRSF2	NP_001182356.1	RRM_SRSF2_SRSF8	16..88	CDD:409751	26/72 (36%)
SRSF2	NP_001182356.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	92..221		31/77 (40%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1169
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.940