Protein Alignment RnpS1 and Pabpn1

DIOPT Version :9

• Sequence 1: NP_649903.1
• Gene: RnpS1 / 41147
• FlyBaseID: FBgn0037707
• Length: 374
• Species: Drosophila melanogaster
• Sequence 2: NP_062275.1
• Gene: Pabpn1 / 54196
• MGIID: 1859158
• Length: 302
• Species: Mus musculus
• Alignment Length: 307
• Identity: 64/307 - (20%)
• Similarity: 113/307 - (36%)
• Gaps: 75/307 - (24%)

  Fly    79 SSSSSSSSSSDSDRSEKNRRR-----GGGAAGK---------------------------DKDKD 111
            :::::::.::....|...|||     .||.||:                           :.:::
Mouse     5 AAAAAAAGAAGGRGSGPGRRRHLVPGAGGEAGEGDPGGAGDYGNGLESEELEPGELLPEPEPEEE 69

  Fly   112 KPSARSRSRSRTRSPRRVSKSPRPGSKARKEPERDRDRRSRSRDRARRAGSNDRAAADSNNVKRE 176
            .|        |.|:|.. :..|.|||.|....|.:.:......|....|..:....|....| ||
Mouse    70 PP--------RPRAPPG-APGPGPGSGAPGSQEEEEEPGLVEADPGDGAIEDPELEAIKARV-RE 124

  Fly   177 RSRSASRSRSPRRRGRGSVERTPPP--------KRRERSRSRTRSPSPKQVRIHVGRLTRNVTKD 233
            ....|.:.:..:......:..:|||        ...|:..:..||       |:||.:....|.:
Mouse   125 MEEEAEKLKELQNEVEKQMNMSPPPGNAGPVIMSLEEKMEADARS-------IYVGNVDYGATAE 182

  Fly   234 HVFEIFSSFGDVKNVEFPVDRF--HPNFGRGVAFVEYATPEDCESAMKHMDGGQIDGQEITVSPV 296
            .:...|...|.|..|....|:|  ||   :|.|::|::..|...:::. :|.....|::|.|.|
Mouse   183 ELEAHFHGCGSVNRVTILCDKFSGHP---KGFAYIEFSDKESVRTSLA-LDESLFRGRQIKVIP- 242

  Fly   297 VLVKQ--RPPMR---RPSPPMR-RPQNNRWRSPPQ--FNRFNNRGGG 335
               |:  ||.:.   |..|..| |.:...:.|...  ::.||:|..|
Mouse   243 ---KRTNRPGISTTDRGFPRSRYRARTTNYNSSRSRFYSGFNSRPRG 286

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RnpS1	NP_649903.1	RRM	<196..>301	CDD:223796	27/114 (24%)
		RRM_RNPS1	221..294	CDD:240811	19/74 (26%)
Pabpn1	NP_062275.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..111		20/114 (18%)
		Interaction with SKIP. /evidence=ECO:0000250	2..141		25/145 (17%)
		RRM	109..>285	CDD:223796	44/191 (23%)
		Stimulates PAPOLA. /evidence=ECO:0000250	115..143		5/28 (18%)
		RRM_II_PABPN1	169..244	CDD:240994	22/89 (25%)
		Strong poly(A) affinity and self-association. /evidence=ECO:0000250	255..302		9/32 (28%)
		Interaction with PAPOLA. /evidence=ECO:0000250	282..302		2/5 (40%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4209
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900