DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment RnpS1 and rnp-5

DIOPT Version :9

Sequence 1:	NP_649903.1	Gene:	RnpS1 / 41147	FlyBaseID:	FBgn0037707	Length:	374	Species:	Drosophila melanogaster
Sequence 2:	NP_001370330.1	Gene:	rnp-5 / 175244	WormBaseID:	WBGene00004388	Length:	289	Species:	Caenorhabditis elegans

Alignment Length:	349	Identity:	140/349 - (40%)
Similarity:	163/349 - (46%)	Gaps:	85/349 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly    39 ERKRRGSASSSSDSRSSTSDSSSSRSSSGSSRSSSSSSSDSSSSSSSSSSDS------DRSEKNR 97
            |.|:|  |.|||.|.||:|.||||.|||..|||||||||..|.|.|....|:      .||....
Worm     6 ETKKR--ARSSSSSSSSSSGSSSSGSSSSGSRSSSSSSSGRSRSRSPRRRDTRPPARGGRSRSPI 68

  Fly    98 RRGGGAAGKDKDKDKPSARSRSRSRTRSPRRVSKSPRPGSKARKEPERDRDRRSRSRDRARRAGS 162
            |||....|...|:|:|...|.|..|.|.|     ||.|       |.|||..||.||.|
Worm    69 RRGSPPRGARADRDRPMRPSPSPPRRRRP-----SPSP-------PRRDRRDRSGSRQR------ 115

  Fly   163 NDRAAADSNNVKRERSRSASRSRSPRRRGRGSVERTPPPKRRERSRSRTRSPSPKQVRIHVGRLT 227
                            |.||..|||                      ..||.||.: |:.:..|:
Worm   116 ----------------RRASPRRSP----------------------AARSASPAK-RVVIKNLS 141

  Fly   228 RNVTKDHVFEIFSSFGDVKNVEFPVDRFHPNFGRGVAFVEYATPEDCESAMKHMDGGQIDGQ--- 289
            |||.|.|:.||||.:|.:|||:.|.||||.:..||..:|||...||.|.::||||||||||.
Worm   142 RNVLKTHLEEIFSIYGAIKNVDLPPDRFHNHVHRGYGYVEYDNLEDAEKSIKHMDGGQIDGMAVH 206

  Fly   290 -EITV--SPVVLVKQRPPMRRPSPPMR---RPQNNRWRSPPQFNRFNNRGGGGGGG-----GGRR 343
             |:|:  ..|...::..|.||.|||.|   .|.....||||...|.:..||.|.|.     ||
Worm   207 VEMTIGRQSVPFQRRSSPFRRRSPPPRDRMSPMRRGGRSPPPHRRRSPMGGRGSGANNMPLGG-- 269

  Fly   344 QSPMRNRRSPRRRSRSPIRRRRRS 367
              |.|.||:  .|||||..||.||
Worm   270 --PNRFRRA--SRSRSPAGRRSRS 289

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
RnpS1	NP_649903.1	RRM	<196..>301	CDD:223796	45/110 (41%)
RnpS1	NP_649903.1	RRM_RNPS1	221..294	CDD:240811	39/78 (50%)
rnp-5	NP_001370330.1	RRM_RNPS1	135..208	CDD:409800	37/72 (51%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	82	1.000	Domainoid score	I5393
eggNOG	1	0.900	-	-		E1_KOG4209
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	165	1.000	Inparanoid score	I2813
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53121
OrthoDB	1	1.010	-	-		D1524222at2759
OrthoFinder	1	1.000	-	-		FOG0003226
OrthoInspector	1	1.000	-	-		otm14223
orthoMCL	1	0.900	-	-		OOG6_103512
Panther	1	1.100	-	-	LDO	PTHR15481
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1169
SonicParanoid	1	1.000	-	-		X3729
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	13	13.000