DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment mura and znrf3

DIOPT Version :9

Sequence 1:	NP_731367.2	Gene:	mura / 41145	FlyBaseID:	FBgn0037705	Length:	1173	Species:	Drosophila melanogaster
Sequence 2:	NP_001072864.1	Gene:	znrf3 / 780325	XenbaseID:	XB-GENE-5937936	Length:	853	Species:	Xenopus tropicalis

Alignment Length:	147	Identity:	47/147 - (31%)
Similarity:	62/147 - (42%)	Gaps:	37/147 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly  1035 EALLSLAERLGEAK---PRGLTRNEIDQLPSYKFNPEVHNGDQSSCVVCMCDFELRQLLRVLPCS 1096
            :||..:..|..:||   ||..:...:|.|.|         ...|.|.:|:..:...:.|||:||:
Frog   230 QALEKMETRKFKAKGKVPREGSCGGLDTLSS---------SSTSDCAICLEKYIDGEELRVIPCT 285

  Fly  1097 HEFHAKCVDKWLRSNRTCPICRGNASDYFDG------VD-------QQQQS------------QA 1136
            |.||.:|||.||..|.|||.||.|..:...|      |:       ||||.            |.
Frog   286 HRFHKRCVDPWLLQNHTCPHCRHNIIEQKKGGHGPVCVENSSNRGRQQQQQRVILPVHYPGRVQR 350

  Fly  1137 TAGAAAALSGTSGGSAG 1153
            |...||..:.||.|..|
Frog   351 TGPIAAYPTRTSMGPHG 367

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
mura	NP_731367.2	zf-RING_2	1076..1118	CDD:290367	19/41 (46%)
znrf3	NP_001072864.1	ZNRF_3_ecto	74..180	CDD:375639
		RING-H2_ZNRF3	266..309	CDD:319713	21/42 (50%)
		RING-H2 finger (C3H2C3-type)	266..306	CDD:319713	19/39 (49%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	583..629
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	650..673
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	685..713
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	834..853
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1487241at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R768
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.950