DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment mura and Zswim2

DIOPT Version :9

Sequence 1:	NP_731367.2	Gene:	mura / 41145	FlyBaseID:	FBgn0037705	Length:	1173	Species:	Drosophila melanogaster
Sequence 2:	NP_082240.1	Gene:	Zswim2 / 71861	MGIID:	1919111	Length:	631	Species:	Mus musculus

Alignment Length:	149	Identity:	40/149 - (26%)
Similarity:	55/149 - (36%)	Gaps:	51/149 - (34%)

- Green bases have known domain annotations that are detailed below.

  Fly  1042 ERLGEAKP------RG----------------LTRNEIDQLPSYKFNPEVHNGDQSSCVVCMCDF 1084
            |..|||||      :|                :|:......|.|:            |.:|:..|
Mouse   299 ENEGEAKPGCFQEKQGQFYTPKHVVKSLPLLMITKKSKLLAPGYQ------------CRLCLKSF 351

  Fly  1085 ELRQLLRVLPCSHEFHAKCVDKW-LRSNRTCPICR----------GNASDYFDGVDQQQQSQATA 1138
            ...|..|:|||:|:||.||:|.| |....:|||.|          |.|:      |.|....|::
Mouse   352 SFGQYTRLLPCTHKFHRKCIDNWLLHKCNSCPIDRQVIYNPLIWKGIAT------DGQAHQLASS 410

  Fly  1139 GAAAALSGTSGGSAGVAGT 1157
            ...|.||........:.||
Mouse   411 KDIACLSKQQEPKLFIPGT 429

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
mura	NP_731367.2	zf-RING_2	1076..1118	CDD:290367	19/42 (45%)
Zswim2	NP_082240.1	SWIM	54..86	CDD:252595
		UBE2D1-binding	139..348		11/60 (18%)
		ZZ	233..>271	CDD:294208
		zf-RING_2	343..386	CDD:290367	19/54 (35%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	589..614
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910