Protein Alignment mura and PJA1

DIOPT Version :9

• Sequence 1: NP_731367.2
• Gene: mura / 41145
• FlyBaseID: FBgn0037705
• Length: 1173
• Species: Drosophila melanogaster
• Sequence 2: NP_001369704.1
• Gene: PJA1 / 64219
• HGNCID: 16648
• Length: 643
• Species: Homo sapiens
• Alignment Length: 793
• Identity: 136/793 - (17%)
• Similarity: 229/793 - (28%)
• Gaps: 286/793 - (36%)

  Fly   419 PQQQQHQI-----NNASAPINSHSQGQGPGNSPNLGHNHQRGYNNGNNNRGIGNGIVNGNTNGPP 478
            |..|:.:|     .|:..|::..:..|....|.:.....:|.:::..:: |....|.|      .
Human    37 PTSQRERIASQRKTNSEVPMHRSAPSQTTKRSRSPFSTTRRSWDDSESS-GTNLNIDN------E 94

  Fly   479 DYMNYRRGVCPAQSRDYSGNGNGNNNGHGHNGRRYMSDNLNNPSSSMNGLINSGHHQRNYNDRNL 543
            ||..|       ..|:|..:|:.....:||.. .|.:|:
Human    95 DYSRY-------PPREYRASGSRRGMAYGHID-SYGADD-------------------------- 125

  Fly   544 NNHFGNSEQNGGPDHRDRAEGSSYNFMRNGGGSGGGGYGRNGSHYQHMAYGNNNGASTSTGGPGL 608
                 :.|:..||..|....                  |:.|.......|....||.:..|.|..
Human   126 -----SEEEGAGPVERPPVR------------------GKTGKFKDDKLYDPEKGARSLAGPPPH 167

  Fly   609 MGE---------------------------LPSGSGLSGSSLSLNNGPGGLNSDSPSRKRRRISG 646
            ...                           ||..|..|.||   :.|......||..|:||.
Human   168 FSSFSRDVREERDKLDPVPAARCSASRADFLPQSSVASQSS---SEGKLATKGDSSERERRE--- 226

  Fly   647 RPPNGPQPQHRCPMA-------HMQQGSPPLRRPRLRDVATSTQQQQQQYGHQVHHPQQQQQQPP 704
              .|.|....|.|::       ..:....|:.||::|::|:....:                  |
Human   227 --QNLPARPSRAPVSICGGGENTSKSAEEPVVRPKIRNLASPNCVK------------------P 271

  Fly   705 SNYHPMHHHQPQPHYVPQQQVPPPHVQRSPW------DLGSSGGSSGGATSSSSVGPILQQVQAP 763
            ..:.........||            ..|.|      :.|.|.|.:......||.|      ...
Human   272 KIFFDTDDDDDMPH------------STSRWRDTANDNEGHSDGLARRGRGESSSG------YPE 318

  Fly   764 PQPPSHQQAVGYPQAPPQPASLMVDLNLNQVPVNLQLRPSEPFWASFCTYPIPAQARLAPCHLHG 828
            |:.|..::.....|..|:           :||...:......||.....|              .
Human   319 PKYPEDKREARSDQVKPE-----------KVPRRRRTMADPDFWTHSDDY--------------Y 358

  Fly   829 VYTQPFPAAPPPGLAAPPLQQQHQPLIQAQQMISQA-----TLTAQQQQRDVVAIATANLGPIEA 888
            .|......:....:||  |:::::   ..:|.:|.:     ||..::::....|..:|:.|....
Human   359 KYCDEDSDSDKEWIAA--LRRKYR---SREQTLSSSGESWETLPGKEEREPPQAKVSASTGTSPG 418

  Fly   889 PGAHGHPHAHPHAHPHAHQLPPGIHITPLSGAAAAAATHHLHSTAAAAAAVAAGAQITTAQQILF 953
            |||                            :|:|.|       .|.|:|.:.|:......:...
Human   419 PGA----------------------------SASAGA-------GAGASAGSNGSNYLEEVREPS 448

  Fly   954 SSDRRTFPPHRRIPRFWTANHGHRHVLPPQSLAAHQAPVQIQATSGIINPGFLLNFLAMFPLSPY 1018
            ..:.:.......||  |...|.:.......:.:.|:          ::.||       :|.|...
Human   449 LQEEQASLEEGEIP--WLQYHENDSSSEGDNDSGHE----------LMQPG-------VFMLDGN 494

  Fly  1019 NQHDLSSGDTNETE------------------------NYEALLSLAERLGEAKPRGL------- 1052
            |..:..|..:.:.|                        .:...::|.|||.:|....|
Human   495 NNLEDDSSVSEDLEVDWSLFDGFADGLGVAEAISYVDPQFLTYMALEERLAQAMETALAHLESLA 559

  Fly  1053 ----------TRNEIDQLPSYKFNPEVHN--GDQSSCVVCMCDFELRQLLRVLPCSHEFHAKCVD 1105
                      ::..||.||..... |.|.  |.:..|.:|..::...::...|||.|.||..||.
Human   560 VDVEVANPPASKESIDALPEILVT-EDHGAVGQEMCCPICCSEYVKGEVATELPCHHYFHKPCVS 623

  Fly  1106 KWLRSNRTCPICR 1118
            .||:.:.|||:||
Human   624 IWLQKSGTCPVCR 636

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mura	NP_731367.2	zf-RING_2	1076..1118	CDD:290367	15/41 (37%)
PJA1	NP_001369704.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..363		74/458 (16%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	380..454		17/111 (15%)
		RING-H2_PJA1_2	594..639	CDD:319379	17/43 (40%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910