Protein Alignment mura and rnf38

DIOPT Version :10

• Sequence 1: NP_731367.2
• Gene: mura / 41145
• FlyBaseID: FBgn0037705
• Length: 1173
• Species: Drosophila melanogaster
• Sequence 2: XP_012819095.2
• Gene: rnf38 / 594927
• XenbaseID: XB-GENE-1015605
• Length: 736
• Species: Xenopus tropicalis
• Alignment Length: 835
• Identity: 224/835 - (26%)
• Similarity: 298/835 - (35%)
• Gaps: 313/835 - (37%)

  Fly   412 SSASSMLPQQQQHQINNA-SAP-------INSHSQGQGPGNSPNLGHNHQRGYNNGNNNRGIGNG 468
            |:|||..||....|:..| |:|       ::|||....|..:|:..|
 Frog    86 SAASSSSPQHPLLQVTTAFSSPSFYQSFSVSSHSTSPSPPTAPSFLH------------------ 132

  Fly   469 IVNGNTNGPPDYMNYRRGVCPAQSRDYSGNGNGNNNGHGHNGRRYMSDNLNNPSSSMNGLINSGH 533
                     |.::.      |.::|..|...:|           :|.:........|.|..:..|
 Frog   133 ---------PVFLE------PPRTRSRSTCRSG-----------FMMNQQQQQLHGMPGAAHFPH 171

  Fly   534 HQ-----------------RNYN-DRNLNNHFGNSEQNGGPDHRDRAEGSSYNFMRNGGGSGGGG 580
            ||                 |..| |||.:.....:.|...|...              ||...|.
 Frog   172 HQLQTPQQPPPPLLFPSALRGINMDRNDSRPPEGARQPHSPPAL--------------GGRRRGN 222

  Fly   581 YGRNGSHYQHMAYGNNNGASTSTGGPGLMGELPSGSGLSGSSLS--------LNNGPGGLNSDSP 637
            ...|.||.||.                   .:.|.:|..|.|..        :.|.....|.|||
 Frog   223 SPNNSSHNQHQ-------------------HMRSPAGNMGPSFQCQPVHQDHICNDDSEKNEDSP 268

  Fly   638 SRKRRRISG-------------------------RPPNGPQPQH-----RCPMAHMQQGSPPLRR 672
            |.||:|:|.                         |||:....||     ||......:.|||:||
 Frog   269 SPKRQRLSNSVFEYAAASPAPSPPMRPWEMTSNRRPPSARPHQHHFSGERCNTPARNRRSPPVRR 333

  Fly   673 PRLRDVATSTQ---QQQQQYGHQVHHPQQQQQQPPSNYHPMHHHQPQPHYVPQQQVPPPHVQRSP 734
            .|.|....|..   .|.:.| |.:.:.|||..:.|..:||       |:..|:...|..|
 Frog   334 QRGRRERLSRHNSISQDENY-HHLSYGQQQAVEEPRAFHP-------PNVSPRMLHPAAH----- 385

  Fly   735 WDLGSSGGSSGGATSSSSVGPILQQVQAPPQPPSHQQAVGYPQAPPQPASLMVDLN--LNQ--VP 795
                                                        |||..::|||::  ::|  ||
 Frog   386 --------------------------------------------PPQQNAVMVDIHEQIHQGTVP 406

  Fly   796 VNLQLRPSEPFWASFCT---YPIPAQARLAPC-------HLHGVYTQPFPAAPPPGLAAPPLQQQ 850
            |:..:....|.....||   .|..:..::..|       ||      |..:.|||.:.|..:|..
 Frog   407 VSYTVTTVAPHGIPLCTGQHIPACSTQQVPGCSVVFSGQHL------PVCSVPPPMIQACSVQHL 465

  Fly   851 HQPLIQAQQMISQATLTAQQQQRDVVAIATANLGPIEAPGAHGHPHAHPHAHPHAHQLPPG---- 911
            ..|......:||.....               |.|         ||..|| | |||..|||
 Frog   466 PVPYAAFPPLISSDPFL---------------LHP---------PHLSPH-H-HAHLPPPGQFVP 504

  Fly   912 -----------IHITPLSGA-----AAAAATHHL--------HSTAAAAAAVAAGAQITT----A 948
                       :|.:||...     .......||        .|..|.....:|..|..|    .
 Frog   505 FQTQQSRSESNLHNSPLQPLQRIENEVELLGEHLPVGGFTYPPSAHAPTLQPSAPLQFITHDPLH 569

  Fly   949 QQILFSSDRRTFPPHRRIPRFWTANHGHR--HVLPPQSLAAHQAPVQIQATSGIINPGFLLNFLA 1011
            |::.|..   .:||.  :||..|..:.:|  ..:||..                .:|..|...|:
 Frog   570 QEVSFGV---PYPPF--MPRRITGRNRYRSQQPIPPPP----------------YHPSLLPYVLS 613

  Fly  1012 MFPLSP------YNQHDLSSGDTNETENYE--ALLSLAERLGEAKPRGLTRNEIDQLPSYKFNPE 1068
            |.|:.|      ..:.|:..|   |.||||  |||:||||||||||||||:.:|:|||||:|||.
 Frog   614 MLPVPPTVGPAFSFELDVEDG---EVENYEVGALLNLAERLGEAKPRGLTKADIEQLPSYRFNPN 675

  Fly  1069 VHNGDQSSCVVCMCDFELRQLLRVLPCSHEFHAKCVDKWLRSNRTCPICRGNASD 1123
            .|..:|:.|||||||||.|||||||||:||||||||||||::||||||||.:||:
 Frog   676 NHQSEQTLCVVCMCDFESRQLLRVLPCNHEFHAKCVDKWLKANRTCPICRADASE 730

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mura	NP_731367.2	RING-H2_RNF38-like	1073..1118	CDD:438135	37/44 (84%)
rnf38	XP_012819095.2	RING-H2_RNF38	662..728	CDD:438341	49/65 (75%)