Protein Alignment mura and rlim

DIOPT Version :10

• Sequence 1: NP_731367.2
• Gene: mura / 41145
• FlyBaseID: FBgn0037705
• Length: 1173
• Species: Drosophila melanogaster
• Sequence 2: XP_686027.4
• Gene: rlim / 562487
• ZFINID: ZDB-GENE-120809-2
• Length: 638
• Species: Danio rerio
• Alignment Length: 710
• Identity: 139/710 - (19%)
• Similarity: 213/710 - (30%)
• Gaps: 250/710 - (35%)

  Fly   509 NGRRYMSDNLNNPSSSMNGLINSGHHQRNYNDRNLNNHFGNSEQNGGPDHRDRAEGSS------- 566
            |..|.:.|...:|||::.            .:|.        |..|..:.....|..|
Zfish    66 NRLRQVKDGPESPSSNIT------------EERR--------EAPGATEVEGTEENPSGETLLDW 110

  Fly   567 YNFMRNGGGSGGGGYGRNGS--------------HYQHMAYGNNNGASTSTGGPGLMG--ELPSG 615
            .|.:|..|.:...||..|.|              .:......|.|.|...|....|.|  |.|.|
Zfish   111 LNTVRQTGNTTRSGYRGNQSWRAVSQTNPNSGDFRFSLEINVNRNIAEQQTQTERLEGSQERPDG 175

  Fly   616 SGLS-----------------------------GSSLSLN---NGPGGLNSDSPSRKRRRISGRP 648
            |...                             .|:|:||   |.|    .|:|:    .::..|
Zfish   176 SVSEPESLMETAEVVEEPVVDELAVIVEPELPVPSTLTLNRDDNVP----VDAPN----PLTSTP 232

  Fly   649 PNGPQ-PQHRCPMAHMQQGSPPLRRPRLRDVATSTQQQQQQYGHQVHHPQQQQQQPPSNYHPMHH 712
            ||.|. .|.|......:..||..||.|.|..                     :.:.|.|...:..
Zfish   233 PNLPSVEQPRRGQIRARSRSPEQRRTRARTA---------------------RGRSPINLERLDG 276

  Fly   713 HQPQPHYVPQQQ---VPPPHVQRSPWDLGSS-------GGSSGGATSSSSVGPILQQVQAPPQPP 767
            ..|..|.:|...   :|.|.|:      |||       ...|...|.:.::|   .....|..|.
Zfish   277 LPPTQHGIPTHNPEILPEPQVE------GSSRTRQLFLSRQSTVETETHTLG---SATDVPEAPQ 332

  Fly   768 SHQQAVGYPQAP-PQPASLMVDLNLNQVPVNLQLRPSEPFWASFCTYPIPAQARLAPCHL----- 826
            ..:...|...|. .:|.::|:||.:.:|      ||.|............::::.:...|
Zfish   333 EREATTGEAGASGRRPPTIMLDLQVRRV------RPGEYRQRDSIANRTRSRSQTSNNTLLYETE 391

  Fly   827 HGVYTQPFPAAPPPGLAA------PPLQQ------QHQPLIQAQQMISQ-------------ATL 866
            .|.:.:.|..:...|:..      .|:::      .....:..|.||.|             |.:
Zfish   392 RGGFRRTFSRSERAGVRTYVSTIRIPIRRISDAGLGEATSLALQSMIRQIMTGFGELSYFMEAEV 456

  Fly   867 TAQQQQRDVVAIATANLGPIEAPGAHGHPHAHPHAHPHAHQLPPGIHITPLSGAAAAAATHHLHS 931
            ....::.:..|..:..||..:|....|...|.|:...|.     |::   ..|..|......:..
Zfish   457 PDSNREDNPPADLSDALGNPDASTGTGASEADPYLPGHG-----GLN---QGGLEARTEEREVEG 513

  Fly   932 TAAAAAAVAAGAQITTAQQILFSSDRRTFPPHRRIPRFWTANHGHRHVLPPQSLAAHQAPVQIQA 996
            ....||.                                          |.::....:||:.:..
Zfish   514 GLPGAAG------------------------------------------PRENRGRQRAPINLDE 536

  Fly   997 TSGIINPGFLLNFLAMFPLSPYNQHDLSSGDTNETENYEALLSLAERLGEAKPRGLTRNEIDQLP 1061
            |..       |.||.:......|:.|                       :.:|||||:.:||.|.
Zfish   537 TGS-------LPFLRLAHFFLLNEED-----------------------DDQPRGLTKEQIDNLS 571

  Fly  1062 SYKFNPEVHNGDQ---SSCVVCMCDFELRQLLRVLPCSHEFHAKCVDKWLRSNRTCPICR 1118
            ...|      |:.   .:|.||:.::.....||.||||||:|..|:|:||..|.||||||
Zfish   572 MRNF------GESDAFKTCSVCITEYAEGNKLRKLPCSHEYHVHCIDRWLSENSTCPICR 625

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mura	NP_731367.2	RING-H2_RNF38-like	1073..1118	CDD:438135	21/47 (45%)
rlim	XP_686027.4	RING-H2_RNF12	582..631	CDD:438336	23/44 (52%)