DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment mura and Rnf115

DIOPT Version :9

Sequence 1:	NP_731367.2	Gene:	mura / 41145	FlyBaseID:	FBgn0037705	Length:	1173	Species:	Drosophila melanogaster
Sequence 2:	XP_006233037.2	Gene:	Rnf115 / 362002	RGDID:	1305315	Length:	423	Species:	Rattus norvegicus

Alignment Length:	400	Identity:	95/400 - (23%)
Similarity:	138/400 - (34%)	Gaps:	96/400 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly   816 PAQARLAPCHLHGVYTQPFPAAPPPG-LAAPPLQQQHQPLIQAQQMISQATLTAQQQQRDVVAIA 879
            ||:..|. |...|    ..|..|..| ..|.||  ...||...:..::.|.|.|..:..:....|
  Rat    32 PARGCLR-CRRAG----SLPLVPGGGPRVARPL--AGGPLGAGRTHVTLAGLGAAGRPEEAATAA 89

  Fly   880 TANLGPIEAPGAHGHPHAHPHAHPHAHQLPPGIHITPLSGAAA----AAATHH------------ 928
            .|.....:...|.|.....|..||     |....:...|.|.|    |.|.|.
  Rat    90 AAAATAAQEVAAWGGTAGRPFGHP-----PQRRKMAEASAAGADAGSAVAAHRFFCHFCKGEVNP 149

  Fly   929 --------------LHSTAAAAAAVAAGAQIT---TA----------QQILFSSDRRTFPPHRRI 966
                          :......::.:..|...|   ||          ...:|..|.|.|.....:
  Rat   150 KLPEYICPRCESGFIEEVTDDSSFLGGGGSRTDNSTATHFAELWDHLDHTMFLQDFRPFLSSNPL 214

  Fly   967 PRFWTAN-HGHR-HV------LPPQSLAAHQ-------APVQIQATSGIIN---PGFLLNFLAMF 1013
            .:...|| .||: |.      .||:.....:       .|.:..|..|||.   .||..|  :..
  Rat   215 DQDNRANERGHQTHTDFWGPSRPPRLPMTRRYRSRGSTRPDRSPAIEGIIQQIFAGFFAN--SAI 277

  Fly  1014 PLSPY----------NQHDLSSGDTNETENYEALLSLAERLGEAKPRGLTRNEIDQLPSYKFNPE 1068
            |.||:          |..|.:.|.|........||...|..|   |....:.:|..||:.....|
  Rat   278 PGSPHPFSWSGMLHSNPGDYAWGQTGLDAIVTQLLGQLENTG---PPPADKEKITSLPTVTVTQE 339

  Fly  1069 -VHNGDQSSCVVCMCDFELRQLLRVLPCSHEFHAKCVDKWLRSNRTCPICRGNASDYFDGVDQQQ 1132
             |:.|  ..|.||..|:.:.:.:|.|||:|.||:.|:..||..:.|||:||.:    .:|.|..:
  Rat   340 QVNTG--LECPVCKEDYTVEEKVRQLPCNHFFHSSCIVPWLELHDTCPVCRKS----LNGEDSTR 398

  Fly  1133 QSQATAGAAA 1142
            |:|::..:|:
  Rat   399 QTQSSEASAS 408

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
mura	NP_731367.2	zf-RING_2	1076..1118	CDD:290367	17/41 (41%)
Rnf115	XP_006233037.2	zinc_ribbon_9	137..167	CDD:405118	0/29 (0%)
Rnf115	XP_006233037.2	RING-H2_RNF115	345..391	CDD:319714	19/49 (39%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910