Protein Alignment mura and Rlim

DIOPT Version :10

• Sequence 1: NP_731367.2
• Gene: mura / 41145
• FlyBaseID: FBgn0037705
• Length: 1173
• Species: Drosophila melanogaster
• Sequence 2: NP_001020063.1
• Gene: Rlim / 317241
• RGDID: 1559832
• Length: 603
• Species: Rattus norvegicus
• Alignment Length: 707
• Identity: 145/707 - (20%)
• Similarity: 228/707 - (32%)
• Gaps: 239/707 - (33%)

  Fly   457 NNGNNNRGIGNGIVNGNTNGPPDYMNYRRGVCPAQSRDYSGNGNGNNNGHGHNGRR-YMSDNLNN 520
            ::..|..|..:..|: |::...|::|             |...:||....|..|.: :.:.:..|
  Rat    78 SSDENRAGESSDDVS-NSDSIIDWLN-------------SVRQSGNTTRSGQRGNQSWRAVSRTN 128

  Fly   521 PSSSMNGLINSGHHQRNYN-DRNLNNHFGNSEQNGGPDHR----DRAEGSSYNFMRNGGGSGGGG 580
            |        |||..:.:.. :.|.||....||....|..|    :..|.||...|.
  Rat   129 P--------NSGDFRFSLEINVNRNNGSQTSENENEPSTRRLSVESMESSSQRQME--------- 176

  Fly   581 YGRNGSHYQHMAYGNNNGASTSTGGPGLMGELPSGSGLSGSSLSLNNGPGGLNSDSPSRKRRRIS 645
                 ||           ||.||.......|..|...|   .:.|..|.....|.||..:|.|
  Rat   177 -----SH-----------ASESTSARPSRAERNSTEAL---EVPLTRGQRRARSRSPEHRRTR-- 220

  Fly   646 GRPPNGPQPQHRCPMAHMQQGSPPLRRPRLRDVATSTQQQQQQYGHQVHH---PQQQQQQPPSNY 707
            .|......|.|           |.:..||                 :.||   ||..:|  |...
  Rat   221 ARAERSRSPLH-----------PTIEIPR-----------------RAHHNISPQTLEQ--PLEN 255

  Fly   708 HPMHHHQPQPHYVPQQQVPPPHVQRSPWDLGSSGGSSGGATSSSSVGPILQQVQAPPQPPSHQQA 772
            .|....:.:.|...:||:..|.:........|...:....||||..|             |:.::
  Rat   256 EPEGSSRTRHHVTLRQQISGPELLGRGLFAASGSRNPSQGTSSSDTG-------------SNSES 307

  Fly   773 VGYPQAPPQPASLMVDLNLNQVPVNLQLRPSEPFWASFCTY----PIPAQAR---LAPCHL---- 826
            .|..|.||   ::::||.:.:|      ||.|        |    .|.::.|   ..|.:.
  Rat   308 SGSGQRPP---TIVLDLQVRRV------RPGE--------YRQRDSIASRTRSRSQTPNNTVTYE 355

  Fly   827 --HGVYTQPFPAAPPPGLAA------PPLQQ------QHQPLIQAQQMISQAT---------LTA 868
              .|.:.:.|..:...|:..      .|:::      .....:..|.|:.|..         :.:
  Rat   356 SERGGFRRTFSRSERAGVRTYVSTIRIPIRRILNTGLSETTSVAIQTMLRQIMTGFGELSYFMYS 420

  Fly   869 QQQQRDVVAIATANLGPIEAPGAHGHPHAHPHAHPHAHQLPPGIHITPLSGAAAAAATHHLHSTA 933
            ........::::.|....|:....|.                       |||..::|       :
  Rat   421 DSDSEPSASVSSRNTERAESRNGRGS-----------------------SGAGNSSA-------S 455

  Fly   934 AAAAAVAAGAQITTAQQILFSSDRRTFP--PHRRIPRFWTANHGHRHVLPPQSLAAHQAPVQIQA 996
            :::.:.::..:.:.:...||.......|  |.||..|                   |:|||....
  Rat   456 SSSPSPSSNGESSESSSDLFEGTSEGGPSGPSRRDGR-------------------HRAPVAFDE 501

  Fly   997 TSGIINPGFLLNFLAMFPLSPYNQHDLSSGDTNETENYEALLSLAERLGEAKPRGLTRNEIDQLP 1061
            :..       |.||::......|:.|                       |.:|||||:.:||.|.
  Rat   502 SGS-------LPFLSLAQFFLLNEDD-----------------------EDQPRGLTKEQIDNLA 536

  Fly  1062 SYKFNPEVHNGDQSSCVVCMCDFELRQLLRVLPCSHEFHAKCVDKWLRSNRTCPICR 1118
            ...|.   .|....:|.||:.::.....||.||||||:|..|:|:||..|.||||||
  Rat   537 MRSFG---ENDALKTCSVCITEYTEGNKLRKLPCSHEYHVHCIDRWLSENSTCPICR 590

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mura	NP_731367.2	RING-H2_RNF38-like	1073..1118	CDD:438135	21/44 (48%)
Rlim	NP_001020063.1	RING-H2_RNF12	547..597	CDD:438336	23/44 (52%)