Protein Alignment mura and Srsf19

DIOPT Version :10

• Sequence 1: NP_731367.2
• Gene: mura / 41145
• FlyBaseID: FBgn0037705
• Length: 1173
• Species: Drosophila melanogaster
• Sequence 2: NP_775611.2
• Gene: Srsf19 / 245492
• MGIID: 3045300
• Length: 829
• Species: Mus musculus
• Alignment Length: 874
• Identity: 168/874 - (19%)
• Similarity: 283/874 - (32%)
• Gaps: 225/874 - (25%)

  Fly   322 HHPNPHHSQYQYQYQYQYRYQYHPPHQYHPLHSPQQQTNRQSLPLTRTNSNSINATTFNSTNPTT 386
            ::.:||::|.......||:|:    .:.|.|   |.:..||....||..:.|           .:
Mouse    91 YNDDPHYAQPDCSSGRQYQYK----EENHDL---QSECERQHFSNTRIQTRS-----------HS 137

  Fly   387 NSNPTDVVNVNSCTDIIPYGSSSTSSSASSMLPQQQQHQINNASAPINSHSQGQGPGNSPNLGHN 451
            .|:..|....:..::.:...||||.....|.:..|   |:.|.:.|.:.:..|:.....|...:.
Mouse   138 RSSGDDSEFKSQSSNHLHRRSSSTRFKTQSSVSTQ---QLPNRACPKSKNLPGKKKKPKPKSSYK 199

  Fly   452 HQRGYNNG----------NNNRGIGNGIVNGNTNGP------PDYMNYRRGVCPAQSRD-YSGNG 499
            ....|.:|          ||.|.:.||..|.....|      ..:....|....:|:|. .....
Mouse   200 SASKYPSGGGLLVGEKLENNQRQVENGQSNSMFEKPCRTKVNATHTLITRPSTRSQTRKRLRSPQ 264

  Fly   500 NGNNNG-----HGHNGRRYMSDNLNNPSSSMNGLINSGHHQRNYNDRNLNNHFGNSEQNGGPDHR 559
            |.:.|.     :..|..|.| :...:||     :|...:..:......|..:
Mouse   265 NSSENSKLERKYAENKERQM-EYPQSPS-----IIKKTYLSKEIEPEILTVY------------- 310

  Fly   560 DRAEGSSYNFMRNGGGSGGGGYGRNGSHYQHMAYGNNNGASTSTGGPGLMGELPSGSGLSGSSLS 624
            ||.:                  .|.....|.:...||:..              .|:..:....|
Mouse   311 DRTQ------------------RRTRRRSQGLPRSNNSNR--------------CGANTADVLHS 343

  Fly   625 LNNGPGGLNSDSPSRKRRRISGRPPNGPQPQHRCPM--AHMQQGSPPLRRPRLRDVAT--STQQQ 685
            :::..|.|||...|.||.::.         ...|..  |:.|..|......|:|....  :|..|
Mouse   344 VDSESGQLNSLQQSEKRTKMG---------IEECGFWTANCQGNSSNDITGRMRFTCNKGNTIPQ 399

  Fly   686 QQQYGHQVH------HPQQQQQQPPSNYHPMHHHQPQPHYVPQQQVPPPHVQRSPWDLGSSGGSS 744
            ....|...|      |.|...|:..|    ||              ..|..|...........:.
Mouse   400 NGLSGLSCHDSNRKIHKQLDYQELES----MH--------------VTPFTQEGNITEVLMEDTC 446

  Fly   745 GGATSSSSVGP----ILQQVQAPPQPPSHQQAVGYPQAPPQPASLMVDLNLNQVPVNLQLRPSEP 805
            ...||:....|    :.:.:::...|.:...|:|.|.         ..|:|....   .||..:.
Mouse   447 SKETSTRRKTPDILTLKETIESRLHPDTKDVALGGPH---------YCLSLETFE---DLRKDKA 499

  Fly   806 FWASFCTYPIPAQARLAPCHLHGVYTQPFPAAPPPGLAAPPLQQQHQPLIQAQQMISQATLTAQQ 870
            :..|.....:|.:..||...|..:|.  ||:.|                 ..:.:::::|....|
Mouse   500 YIFSNSHTFLPLRDNLAISELQKLYF--FPSFP-----------------TIEHILTESTAHRSQ 545

  Fly   871 QQRDVVAIATANLGPIEAPGAHGHPHAHPHAHPHAHQLPPGIHITPLSGAAAAAATHHLHSTAAA 935
                     :.::.|.:..........|......::|  ..|.|:.:........| :|..|..:
Mouse   546 ---------STSVTPTKFTTVEIDQKEHTKTSSCSNQ--TDIQISDVISDDETLNT-NLECTIPS 598

  Fly   936 AAAVAAG---------------AQITTAQQILFSSDRRTFPPHRRIPRFWTA-----------NH 974
            |....:|               ..:.:...:...::||....|.||.|..::           ||
Mouse   599 APCETSGNIMLGVFEVDDNFTEFDLQSCDSLSSQNNRRVHSGHSRISRSVSSLNSNSTTSSSTNH 663

  Fly   975 G-------HRHVLPPQSLAAH--QAPVQIQATSGIINPGFLLNFLAMFPLSPY---NQHDLSSGD 1027
            .       .:..||..|.:.:  ...:.:..||.|....   |...:|...|:   .|..::|.:
Mouse   664 SLLSLLNYSQQFLPVSSTSDNIIGNDINLPHTSQINQES---NEFIVFNCPPFEARQQMHVTSPE 725

  Fly  1028 TNETENYEALL---SLAERLGEAKPRGLTRNEIDQLPSYKFNPEVHNGDQSSCVVCMCDFELRQL 1089
            |:...:|..:|   |....:....|:|||..:|:.||...|   ..|.:.|.|.:|:..:.....
Mouse   726 TSNDSDYWPVLPDFSNFNDIHNNHPKGLTEEQINNLPVIYF---CENDEISHCSICLTQYIKNSK 787

  Fly  1090 LRVLPCSHEFHAKCVDKWLRSNRTCPICR 1118
            :|||||.||:|.||:|:||..|.||||||
Mouse   788 IRVLPCFHEYHDKCIDRWLSDNSTCPICR 816

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mura	NP_731367.2	RING-H2_RNF38-like	1073..1118	CDD:438135	21/44 (48%)
Srsf19	NP_775611.2	RRM_SF	16..88	CDD:473069
		RING-H2_RNF6-like	775..816	CDD:438130	20/40 (50%)