Protein Alignment mura and RNF44

DIOPT Version :9

• Sequence 1: NP_731367.2
• Gene: mura / 41145
• FlyBaseID: FBgn0037705
• Length: 1173
• Species: Drosophila melanogaster
• Sequence 2: NP_055716.1
• Gene: RNF44 / 22838
• HGNCID: 19180
• Length: 432
• Species: Homo sapiens
• Alignment Length: 556
• Identity: 173/556 - (31%)
• Similarity: 219/556 - (39%)
• Gaps: 177/556 - (31%)

  Fly   598 GASTSTGGPG-LMGELPSGSGLSGSSLSLNNGPGGLNSDSPSRKRRRISGRPPNGPQPQHRCPMA 661
            |....:.||| ..|:|....||.|...|           .|:|..|..|.:||:  :|.| .|:.
Human    18 GQRRFSAGPGSTPGQLWGSPGLEGPLAS-----------PPARDERLPSQQPPS--RPPH-LPVE 68

  Fly   662 HMQQGSPPLRRPRLRDVATSTQQQQQQYGHQVHHPQQQQQQPPSNYHPMHHHQPQP-HY----VP 721
            ..:..:|....||:.                  ||..||.....:.|...|..|.| .|    |.
Human    69 ERRASAPAGGSPRML------------------HPATQQSPFMVDLHEQVHQGPVPLSYTVTTVT 115

  Fly   722 QQQVPPPHVQRSPWDLGSSGGSSGGATSSSSVGPILQQVQAPPQPPSHQQAVGYPQA--PPQPAS 784
            .|..|.|..|..|                   |...||:.|.....|.|.   ||..  ||   .
Human   116 TQGFPLPTGQHIP-------------------GCSAQQLPACSVMFSGQH---YPLCCLPP---P 155

  Fly   785 LMVDLNLNQVPVNLQLRPSEPFWASFCTYPIPAQARLAPCHL----HGVYTQPFPAAPP-PGLAA 844
            |:....:.|:||        |:.|    ||          ||    |.:...|.||.|| |...|
Human   156 LIQACTMQQLPV--------PYQA----YP----------HLISSDHYILHPPPPAPPPQPTHMA 198

  Fly   845 P-----PLQQQHQPLIQAQQMISQATLTAQQQQRDVVAIATANLGPIEAPGA--HGHPHAHPHAH 902
            |     .||.|| |.:..|::.:...|...|........:|:..||..:|..  |..||...|..
Human   199 PLGQFVSLQTQH-PRMPLQRLDNDVDLRGDQPSLGSFTYSTSAPGPALSPSVPLHYLPHDPLHQE 262

  Fly   903 -----PHAHQLPPGIHITPLSGAAAAAATHHLHSTAAAAAAVAAGAQITTAQQILFSSDRRTFPP 962
                 |::|.:|
Human   263 LSFGVPYSHMMP----------------------------------------------------- 274

  Fly   963 HRRIPRFWTANHGHRHVLPPQSLAAHQAPVQIQATSGIINPGFLLNFLAMFPLSPYNQH-----D 1022
             ||:.   |..:..:..|||........|..         |.||..||:|.|:||....     |
Human   275 -RRLS---TQRYRLQQPLPPPPPPPPPPPYY---------PSFLPYFLSMLPMSPTAMGPTISLD 326

  Fly  1023 LSSGDTNETENYEALLSLAERLGEAKPRGLTRNEIDQLPSYKFNPEVHNGDQSSCVVCMCDFELR 1087
            |...|. |.|||||||:||||||:|||||||:.:|:|||||:|||:.|..:|:.||||..|||.|
Human   327 LDVDDV-EMENYEALLNLAERLGDAKPRGLTKADIEQLPSYRFNPDSHQSEQTLCVVCFSDFEAR 390

  Fly  1088 QLLRVLPCSHEFHAKCVDKWLRSNRTCPICRGNASD 1123
            ||||||||:||||.|||||||::||||||||.:||:
Human   391 QLLRVLPCNHEFHTKCVDKWLKANRTCPICRADASE 426

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mura	NP_731367.2	zf-RING_2	1076..1118	CDD:290367	33/41 (80%)
RNF44	NP_055716.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..86		23/99 (23%)
		RING-H2_RNF38_like	377..421	CDD:319386	34/43 (79%)
		RING-H2 finger (C3H2C3-type)	380..420	CDD:319386	32/39 (82%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E33208_3BGBB
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S6400
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0003478
OrthoInspector	1	1.000	-	-		otm41592
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR46171
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	7	6.820