Protein Alignment mura and ZNRF2

DIOPT Version :10

• Sequence 1: NP_731367.2
• Gene: mura / 41145
• FlyBaseID: FBgn0037705
• Length: 1173
• Species: Drosophila melanogaster
• Sequence 2: NP_667339.1
• Gene: ZNRF2 / 223082
• HGNCID: 22316
• Length: 242
• Species: Homo sapiens
• Alignment Length: 259
• Identity: 60/259 - (23%)
• Similarity: 87/259 - (33%)
• Gaps: 87/259 - (33%)

  Fly   879 ATANLGPIEAPGAHGHPHAHPHAHPHAHQLPPGIHITPLSGAAAAA------ATHHLHSTAAAAA 937
            |.|...|.:.|.||         .|.|.           .||||||      |.....|...|..
Human    44 AAAGRFPAQVPSAH---------QPSAS-----------GGAAAAAAAPAAPAAPRSRSLGGAVG 88

  Fly   938 AVAAGAQITTAQQILFSSDRRTFPPHRRIPRFWTANHGHR---HVLPPQSLAAHQAPVQIQATSG 999
            :||:||:   |.|..||           ||...:..:|.:   |..|.........||     .|
Human    89 SVASGAR---AAQSPFS-----------IPNSSSGPYGSQDSVHSSPEDGGGGRDRPV-----GG 134

  Fly  1000 IINPGFLLNFLAMFP--LSPYNQHDLSSGDTNETENYEALLSLAERLGEAK----PRGLTRNEID 1058
              :||.....:...|  |||:                        ..|..|    .:.::.:|:|
Human   135 --SPGGPRLVIGSLPAHLSPH------------------------MFGGFKCPVCSKFVSSDEMD 173

  Fly  1059 -------QLPSYKFNPEVHNGDQSSCVVCMCDFELRQLLRVLPCSHEFHAKCVDKWLRSNRTCP 1115
                   ..|...:|.:|.:.|...|.:|:.:.:....:..|||...:|..|:|:|...||:||
Human   174 LHLVMCLTKPRITYNEDVLSKDAGECAICLEELQQGDTIARLPCLCIYHKGCIDEWFEVNRSCP 237

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mura	NP_731367.2	RING-H2_RNF38-like	1073..1118	CDD:438135	14/43 (33%)
ZNRF2	NP_667339.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..141		35/137 (26%)
		mRING-CH-C4HC2H_ZNRF2	187..242	CDD:438356	16/51 (31%)