DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment mura and Znrf4

DIOPT Version :9

Sequence 1:	NP_731367.2	Gene:	mura / 41145	FlyBaseID:	FBgn0037705	Length:	1173	Species:	Drosophila melanogaster
Sequence 2:	NP_035613.2	Gene:	Znrf4 / 20834	MGIID:	1341258	Length:	327	Species:	Mus musculus

Alignment Length:	359	Identity:	72/359 - (20%)
Similarity:	108/359 - (30%)	Gaps:	151/359 - (42%)

- Green bases have known domain annotations that are detailed below.

  Fly   806 FWASFCTYPIPAQARLAPCH------LHGVYTQPFPAAPPPGLAAP---------PLQQQH--QP 853
            ||......|..||..|:...      |.||...|..|.....:|.|         |....|  .|
Mouse    17 FWLVLSLSPTDAQVNLSSVDFLDLPALLGVPVDPKRARGYLLVARPADACHAIEGPWPDNHSLDP 81

  Fly   854 LIQAQQMISQATLTAQQQQRDVVAIATANLGPIEAPGAHGH------------------PHAHPH 900
            |:..:.:......|.::.||  .....|::|| ||||....                  |||.|.
Mouse    82 LVLVRPLGCSWEQTGRRAQR--AGATAASVGP-EAPGQLREFEDLEVTVRCDQPARVLLPHAEPC 143

  Fly   901 AHPHAHQLPPGIHITPLSGAAAAAATHHLHSTAAAAAAVAAGAQITTAQQILFSSDRRTFPPHRR 965
            ..|..|         |:..|:.|         .|.|.|:||......         |:.:|
Mouse   144 PDPECH---------PVVVASWA---------LARALALAASTLFVL---------RQLWP---- 177

  Fly   966 IPRFWTANHGHRHVLPPQSLAAHQAPVQIQATSGIINPGFLLNFLAMFPLSPYNQHDLSSGDTNE 1030
                |....|.|                                                |...:
Mouse   178 ----WVRGLGSR------------------------------------------------GTAVK 190

  Fly  1031 TENYEALLSLAERLGEAKPRGLTRNEIDQLPSYKFNPEVHNGDQSSCVVCMCDFELRQLLRVLPC 1095
            |:..:          :|:.|..||  :..|                |.:|:.|:|..:.|::|||
Mouse   191 TQTCQ----------KAQVRTFTR--LSDL----------------CAICLDDYEEGERLKILPC 227

  Fly  1096 SHEFHAKCVDKWL--RSNRTCPICRGNASDYFDG 1127
            :|.:|.:|:|.|.  .:.|:||:|:.:.:...||
Mouse   228 AHAYHCRCIDPWFSRAAQRSCPLCKQSVASTHDG 261

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
mura	NP_731367.2	zf-RING_2	1076..1118	CDD:290367	16/43 (37%)
Znrf4	NP_035613.2	PA_C_RZF_like	19..156	CDD:239038	33/148 (22%)
		zf-RING_2	207..252	CDD:290367	17/60 (28%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	256..279		2/6 (33%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1487241at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920