Protein Alignment mura and Rlim

DIOPT Version :10

• Sequence 1: NP_731367.2
• Gene: mura / 41145
• FlyBaseID: FBgn0037705
• Length: 1173
• Species: Drosophila melanogaster
• Sequence 2: NP_035406.3
• Gene: Rlim / 19820
• MGIID: 1342291
• Length: 600
• Species: Mus musculus
• Alignment Length: 727
• Identity: 144/727 - (19%)
• Similarity: 232/727 - (31%)
• Gaps: 248/727 - (34%)

  Fly   498 NGNGNNNGHGHNG--RRYMSDNLNNPSSSMNGLIN-SGHHQRNYNDRNLNNHFGNSEQN------ 553
            |.:.|:.|...:.  ||...|.|:...:....:.| |....|...|.||....|.|.:.
Mouse     3 NSDSNDKGSDQSAAQRRSQMDRLDREEAFYQFVNNLSEEDYRLMRDNNLLGTPGESTEEELLRRL 67

  Fly   554 ---------GGPDHRDRAEGSS-----------YNFMRNGGGSGGGGYGRNGSHYQHMAYGN--- 595
                     ..||.....|.|.           .|.:|..|.:...|. |....::.::..|
Mouse    68 QQIKEGPPPQSPDENRAGESSDDVTNSDSIIDWLNSVRQTGNTTRSGQ-RGNQSWRAVSRTNPNS 131

  Fly   596 -------------NNGASTSTGGPGLMGELPSGSGL------SGSSLSLNNGPGGLNSDSPSRKR 641
                         |||:.||..     ...||...|      |.|...:.|......|..|||..
Mouse   132 GDFRFSLEINVNRNNGSQTSEN-----ESEPSTRRLSVENMESSSQRQMENSASESASARPSRAE 191

  Fly   642 RR----ISGRPPNGPQ-------PQHRCPMAHMQQGSPPL--------RRPRLRDVATSTQQQQQ 687
            |.    ::..|....|       |:||...|..::...||        |.|.|.
Mouse   192 RNSAEAVTEVPTTRAQRRARSRSPEHRRTRARAERSRSPLQPTSEIPRRAPTLE----------- 245

  Fly   688 QYGHQVHHPQQQQQQPPSNYHPMHHHQPQPHYVPQQQVPPPHVQRSPWDLGSSGGSSGGATSSSS 752
                     |..:.:|..:....|      |...:||:..|.:........|...:....||||.
Mouse   246 ---------QSSENEPEGSSRTRH------HVTLRQQISGPELLGRGLFAASGSRNPSQGTSSSD 295

  Fly   753 VGPILQQVQAPPQPPSHQQAVGYPQAPPQPASLMVDLNLNQVPVNLQLRPSEPFWASFCTY---- 813
            .|             |:.::.|..|.||   ::::||.:.:|      ||.|        |
Mouse   296 TG-------------SNSESSGSGQRPP---TIVLDLQVRRV------RPGE--------YRQRD 330

  Fly   814 PIPAQAR---LAPCHL------HGVYTQPFPAAPPPGLAA------PPLQQ------QHQPLIQA 857
            .|.::.|   .||.:.      .|.:.:.|..:...|:..      .|:::      .....:..
Mouse   331 SIASRTRSRSQAPNNTVTYESERGGFRRTFSRSERAGVRTYVSTIRIPIRRILNTGLSETTSVAI 395

  Fly   858 QQMISQAT---------LTAQQQQRDVVAIATANLGPIEAPGAHGHPHAHPHAHPHAHQLPPGIH 913
            |.|:.|..         :.:........::::.|:..:|:....|.
Mouse   396 QTMLRQIMTGFGELSYFMYSDSDSEPSASVSSRNVERVESRNGRGS------------------- 441

  Fly   914 ITPLSGAAAAAATHHLHSTAAAAAAVAAGAQITTAQQILF--SSDRRTFPPHRRIPRFWTANHGH 976
                ||...::.     |:::::.:.::..:.:.:...:|  ||:..:..|.||..|
Mouse   442 ----SGGGNSSG-----SSSSSSPSPSSSGESSESSSEMFEGSSEGGSSGPSRRDGR-------- 489

  Fly   977 RHVLPPQSLAAHQAPVQIQATSGIINPGFLLNFLAMFPLSPYNQHDLSSGDTNETENYEALLSLA 1041
                       |:|||....:..       |.||::......|:.|
Mouse   490 -----------HRAPVTFDESGS-------LPFLSLAQFFLLNEDD------------------- 517

  Fly  1042 ERLGEAKPRGLTRNEIDQLPSYKFNPEVHNGDQSSCVVCMCDFELRQLLRVLPCSHEFHAKCVDK 1106
                |.:|||||:.:||.|....|.   .|....:|.||:.::.....||.||||||:|..|:|:
Mouse   518 ----EDQPRGLTKEQIDNLAMRSFG---ENDALKTCSVCITEYTEGNKLRKLPCSHEYHVHCIDR 575

  Fly  1107 WLRSNRTCPICR 1118
            ||..|.||||||
Mouse   576 WLSENSTCPICR 587

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mura	NP_731367.2	RING-H2_RNF38-like	1073..1118	CDD:438135	21/44 (48%)
Rlim	NP_035406.3	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..24		5/20 (25%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	49..355		70/367 (19%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	417..497		17/126 (13%)
		RING-H2_RNF12	544..594	CDD:438336	23/44 (52%)
		PDZ-binding. /evidence=ECO:0000255	597..600