DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment mura and rnf130

DIOPT Version :9

Sequence 1:	NP_731367.2	Gene:	mura / 41145	FlyBaseID:	FBgn0037705	Length:	1173	Species:	Drosophila melanogaster
Sequence 2:	NP_001107712.1	Gene:	rnf130 / 100124963	XenbaseID:	XB-GENE-949564	Length:	419	Species:	Xenopus tropicalis

Alignment Length:	173	Identity:	45/173 - (26%)
Similarity:	73/173 - (42%)	Gaps:	50/173 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly  1024 SSGDTNETENYEALLSLAERLGEAKPRGL----TRNEIDQLPSYKFNPEVHNGDQSS------CV 1078
            |:.|.|:           .|||:|..:.:    ||.             |..||:.:      |.
Frog   225 SARDRNQ-----------RRLGDAAKKAIGKLTTRT-------------VKKGDKETDPDFDHCA 265

  Fly  1079 VCMCDFELRQLLRVLPCSHEFHAKCVDKWLRSNRTCPICR-------GNASDY-------FDGVD 1129
            ||:..::...::|||||.|.||..|||.||..:.|||:|:       |.|::.       || ::
Frog   266 VCIESYKQNDIVRVLPCKHVFHKVCVDPWLSEHCTCPMCKLNILKALGIAANVPCTDNVAFD-ME 329

  Fly  1130 QQQQSQATAGAAAALSGTSGGSAGVAGTSEASAATANPQQSQA 1172
            :..:||..:..:|....|..||..:. :..:|..:..|...:|
Frog   330 RLTRSQPPSRRSAPNDPTEEGSLSLE-SLRSSRISQGPHDVEA 371

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
mura	NP_731367.2	zf-RING_2	1076..1118	CDD:290367	19/47 (40%)
rnf130	NP_001107712.1	PA_GRAIL_like	41..179	CDD:239037
		HRD1	<197..344	CDD:227568	39/143 (27%)
		RING_Ubox	262..310	CDD:388418	20/47 (43%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1487241at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010