Protein Alignment by and tns2b

DIOPT Version :10

• Sequence 1: NP_649901.1
• Gene: by / 41144
• FlyBaseID: FBgn0000244
• Length: 720
• Species: Drosophila melanogaster
• Sequence 2: XP_021327488.2
• Gene: tns2b / 565809
• ZFINID: ZDB-GENE-101001-5
• Length: 1445
• Species: Danio rerio
• Alignment Length: 677
• Identity: 210/677 - (31%)
• Similarity: 312/677 - (46%)
• Gaps: 170/677 - (25%)

  Fly   133 SPLLVRKTLGNAVSPTSSTNTNTIANTYHYTSSSATPTPVRDNFEQLLRERREKVYN-EYRNLDR 196
            ||...|.:.|.| |.:.|.|::.||         .||:|.|.|..:...|..:...| ||..:
Zfish   845 SPQPFRDSPGYA-SISHSQNSSPIA---------LTPSPKRANHNRASAEENQHGPNEEYTKI-- 897

  Fly   197 ESSGERARVAPAPPQRQYYP-SDGYGIGLKN--DSN--GTLYRKSPSSNGKSTKYNYDFEFNLNL 256
             .|.:::....:||.:...| ..|..:.:|:  |.|  .:|.....|::|...|...
Zfish   898 -LSDDKSPATFSPPTQNSGPVKAGEMVQIKSPEDVNLPVSLITNISSASGAEDKTTI-------- 953

  Fly   257 DDVRPEPTPYTTRNIHFEDLRLDQDVPDGVVNRRTMERNYHTINSLETTHKRQQLEPLEQLGAVY 321
                   |..|:.::              :::.:...:|..:: .::|.:.|....|
Zfish   954 -------TDCTSNSL--------------LISSQPSSKNMESV-QVQTLNPRPLSVP-------- 988

  Fly   322 GQNHMEETLTRTRRDLSASTSTSKSTSPLPAIGVPAIAPASPIYATSTKRVSNPNTNGQQQ-MTP 385
                 |....:..|..|..|||:.||||.|        |......:|....|:.|.||::| :||
Zfish   989 -----ESEQDKGERPGSCYTSTTTSTSPQP--------PLCSSERSSASEFSSFNLNGERQSVTP 1040

  Fly   386 ------SPTSRPE---TPAFPV---------TPRTPF---------------------------- 404
                  ...|.|:   ||:||:         .|..|:
Zfish  1041 LTDCNEESNSDPDGFITPSFPIASHGYPLLTVPHVPYTGYTEITIPTNLAQPPLPEKQRSSPLHN 1105

  Fly   405 -------------GASSSSSASL-----APTTQLPPESIYQTGPRRGVPPALQPLEVSAD----- 446
                         |..|.|||.:     ..|.::||:|..:.           ||....|
Zfish  1106 TSDYTPTSLIKSAGKPSVSSAQVHVSFSTTTNEVPPKSTCRI-----------PLSSGVDEPESR 1159

  Fly   447 -SVQFARSSSQFWYKPNLTREDAIALLASAQPGTFLVRDSTTYKDSYGLVVRVSQPP-------- 502
             |.:|.:.||::||||.::|:.|||:|...:.|.||:|||.:::.:|||.::||..|
Zfish  1160 LSSKFVQDSSKYWYKPGISRDQAIAVLKDKEAGCFLIRDSNSFQGAYGLALKVSTAPAHTNSHTE 1224

  Fly   503 PGS--QELVRHFLIEPTKGGVHLKGCDDEPVFTSLSALVFEHSISQLALPCLLRLPDRDIVPPVR 565
            |||  ::||||||||....||.:|||.:|..|.||||||::|||:.::|||:||:||||:|..::
Zfish  1225 PGSAQEQLVRHFLIESGAKGVKIKGCQNETYFGSLSALVYQHSITPVSLPCVLRIPDRDLVGELQ 1289

  Fly   566 -----ATTPAQQHLLAHGAATNVLWLYSCDTESLTGNEAIRKAIRQMYGQQPLPQPTEVHFKVSS 625
                 ..|.....||..|||.|||:|.|.:||||||.:|:.|..:....|:|.|.||.||||||:
Zfish  1290 DLQSGTNTSTAADLLKQGAACNVLYLNSVETESLTGPQAVSKTTKCTLTQEPRPSPTVVHFKVST 1354

  Fly   626 QGITLTDNTRKKFFRKHYKADVISHCAIDPENRMWTSEGESDKKTIFAFVARRSHSSTDNQCHVF 690
            ||||||||.|:.|||:||....::..::||.::.|.....:..| :|.|||||| .:..|.||:|
Zfish  1355 QGITLTDNQRRLFFRRHYPIHSVTFSSVDPLDQRWVDADNTSCK-MFGFVARRS-GALGNVCHLF 1417

  Fly   691 CDLSVSQPAAAIVSFANRT-LPTEKLR 716
            .:|...|||.|||:|.|:. |..::||
Zfish  1418 AELDPEQPATAIVNFINKVMLGPQQLR 1444

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
by	NP_649901.1	SH2_Tensin_like	454..559	CDD:198181	57/114 (50%)
		PTB_tensin	578..711	CDD:269924	65/133 (49%)
tns2b	XP_021327488.2	None