Protein Alignment by and Tns2

DIOPT Version :9

• Sequence 1: NP_001163569.1
• Gene: by / 41144
• FlyBaseID: FBgn0000244
• Length: 720
• Species: Drosophila melanogaster
• Sequence 2: XP_030104299.1
• Gene: Tns2 / 209039
• MGIID: 2387586
• Length: 1408
• Species: Mus musculus
• Alignment Length: 631
• Identity: 213/631 - (33%)
• Similarity: 294/631 - (46%)
• Gaps: 119/631 - (18%)

  Fly   134 PLLVRKTLGNAVS--------PTSS--TNTNTIANTYHYTSSSATPTPV-RD---NFEQLLRERR 184
            |.|..:.||..:|        |.|.  .:|..:|:|..:...|.:|.|. ||   ....|.|..|
Mouse   838 PYLQPRKLGYEISAEDGRDKYPLSGHLASTGPLASTELFPPVSESPEPSWRDGSSGHSTLPRSPR 902

  Fly   185 EKVYNEYRNLDRESSGERARVAPAPPQRQYYPSDGYGIGLKNDSNGTLYRKSPSSNGKSTKYNYD 249
                      |.:.|.......|:.|                     |:..|| ..||
Mouse   903 ----------DPQCSASSELSGPSTP---------------------LHTSSP-VQGK------- 928

  Fly   250 FEFNLNLDDVRPEPTPYTTRNIHFEDLRLDQDVPDGV--VNRRTMERNYHTINSLETTHKRQQLE 312
             |.|...|..|......|.|      |...:.:|..|  |..:|.|        |.|:.:.:||:
Mouse   929 -ESNRRQDTTRSPSLAPTQR------LSPGEALPSVVQGVAEKTPE--------LLTSSRPEQLD 978

  Fly   313 --PLEQLGAVYGQNHMEETLTRTRRDLSASTSTSKSTSPLPAIGVPAI--APASPIYATSTKRVS 373
              |..|..|....|...:     .|.....|:::...||:|.. :|.:  ||......||.....
Mouse   979 PSPFSQTSAPGSPNGWPQ-----ERSPGGHTNSASPRSPVPTT-LPGLRHAPWQGPRGTSDSPDG 1037

  Fly   374 NPNTNGQQQM-----TPSPTSRPETPAFPVTPRTPFGASSSSSASLAPTTQLPPESIYQTGPRRG 433
            :|.|....||     :|.|.....|||||:.  |.:.|:......|.....||......:.|.|.
Mouse  1038 SPLTPVPTQMPWLVGSPEPPQSSPTPAFPLA--TSYDANGPIQPPLPEKRHLPGSGQQPSPPARS 1100

  Fly   434 V---------------PPALQPLEVSADSVQFARSSSQFWYKPNLTREDAIALLASAQPGTFLVR 483
            .               ||. .||:.:..:|:|.:.:|:|||||:|:|:.|||||....||.||:|
Mouse  1101 TNQHVTFASPLPDVTQPPE-HPLQENQSNVKFVQDTSKFWYKPHLSRDQAIALLKDKDPGAFLIR 1164

  Fly   484 DSTTYKDSYGLVVRVSQPPPG--------SQELVRHFLIEPTKGGVHLKGCDDEPVFTSLSALVF 540
            ||.:::.:|||.::|:.|||.        |::||||||||....||.:|||..||.|.||||||.
Mouse  1165 DSHSFQGAYGLALKVATPPPSAQPWKGDPSEQLVRHFLIETGPKGVKIKGCPTEPYFGSLSALVS 1229

  Fly   541 EHSISQLALPCLLRLPDRDIV-----PPVRATTPAQQHLLAHGAATNVLWLYSCDTESLTGNEAI 600
            :||||.::|||.||:|.:|.:     .||.........||..|||.:||:|.|.:||||||.:|:
Mouse  1230 QHSISPISLPCCLRIPSKDPLEETPEAPVPTNMSTAADLLRQGAACSVLYLTSVETESLTGPQAV 1294

  Fly   601 RKAIRQMYGQQPLPQPTEVHFKVSSQGITLTDNTRKKFFRKHYKADVISHCAIDPENRMWTS-EG 664
            .||........|:|.|..||||||:||||||||.||.|||:||..:.|:..:.||::|.||: :|
Mouse  1295 AKASSAALSCSPVPVPAIVHFKVSAQGITLTDNQRKLFFRRHYPVNSITFSSTDPQDRRWTNPDG 1359

  Fly   665 ESDKKTIFAFVARRSHSSTDNQCHVFCDLSVSQPAAAIVSFANRTL 710
            .:.|  ||.|||::..|..:|.||:|.:|...|||:|||:|..:.|
Mouse  1360 ATSK--IFGFVAKKPGSPWENVCHLFAELDPDQPASAIVTFITKVL 1403

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
by	NP_001163569.1	SH2_Tensin_like	454..559	CDD:198181	60/112 (54%)
		PTB_tensin	578..711	CDD:269924	67/134 (50%)
Tns2	XP_030104299.1	C1	33..80	CDD:237996
		PTP_DSP_cys	133..291	CDD:391942
		PTEN_C2	298..425	CDD:371036
		PHA03247	<726..1124	CDD:223021	79/348 (23%)
		SH2_Tensin_like	1135..1248	CDD:198181	60/112 (54%)
		PTB_tensin	1272..1404	CDD:269924	67/134 (50%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	138	1.000	Domainoid score	I4813
eggNOG	1	0.900	-	-		E2759_KOG1930
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm44309
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR45734
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R5448
SonicParanoid	1	1.000	-	-		X1051
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	8	7.900